5f. Complete the diagrams below to reflect the proteins and any relevant cofactors (e.g. - inducer/repressor molecules) that you would expect to be occupying this operon's regulatory region in the presence of low vs high fatty acyl CoA levels. ↑ [hexose], [fatty acyl CoA] = negligible [hexose] = negligible, T[ fatty acyl CoA] promoter operator promoter operator 5g. A mutation has occurred rendering the regulatory protein unable to recognize the operator sequence. What effect would this have on the expression of this operon? How would this impact the energetic demands on the cell? Justify your answer.

Human Anatomy & Physiology (11th Edition)
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Chapter1: The Human Body: An Orientation
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5f. Complete the diagrams below to reflect the proteins and any relevant cofactors (e.g. -
inducer/repressor molecules) that you would expect to be occupying this operon's regulatory
region in the presence of low vs high fatty acyl CoA levels.
↑ [hexose], [fatty acyl CoA] = negligible
[hexose] = negligible, T[ fatty acyl COA]
promoter
operator
promoter
operator
5g. A mutation has occurred rendering the regulatory protein unable to recognize the operator
sequence. What effect would this have on the expression of this operon? How would this impact
the energetic demands on the cell? Justify your answer.
Transcribed Image Text:5f. Complete the diagrams below to reflect the proteins and any relevant cofactors (e.g. - inducer/repressor molecules) that you would expect to be occupying this operon's regulatory region in the presence of low vs high fatty acyl CoA levels. ↑ [hexose], [fatty acyl CoA] = negligible [hexose] = negligible, T[ fatty acyl COA] promoter operator promoter operator 5g. A mutation has occurred rendering the regulatory protein unable to recognize the operator sequence. What effect would this have on the expression of this operon? How would this impact the energetic demands on the cell? Justify your answer.
Like the lac operon, the hexose operon is controlled by a separate regulatory protein under the control
of its own promoter (see the schematic of the operon below). The hexose regulatory protein is
sensitive to fatty acyl CoA levels. When all hexose fuel sources are depleted, the bacteria switch to
lipid metabolism and fatty acyl CoA levels increase. This turns expression of the hexose operon off.
+1
+1
Regulatory Gene
regulator
Hexose Operon Genes
operon
regulator promoter
operon promoter
Transcribed Image Text:Like the lac operon, the hexose operon is controlled by a separate regulatory protein under the control of its own promoter (see the schematic of the operon below). The hexose regulatory protein is sensitive to fatty acyl CoA levels. When all hexose fuel sources are depleted, the bacteria switch to lipid metabolism and fatty acyl CoA levels increase. This turns expression of the hexose operon off. +1 +1 Regulatory Gene regulator Hexose Operon Genes operon regulator promoter operon promoter
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