3. All the following statements about chemical degradation are true except |A) as temperature increases, degradation decreasesB) chemical degradation may produce a toxic productC) chemical degradation may result in loss of active ingredientsD) chemical degradation may affect the therapeutic activity of a drug product

A) As temperature increases, degradation decreasesThis statement is false because chemical…

Answered: 3. All the following statements about…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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6. The zero-order rate constant for a drug degradation is 0.05 mg/mL yr. If a 1g/100mL solution is prepared and stored, what is the shelf-life of the drug? A) 2 months B) 20 months C) 2 years D) 20 years
Tylenol 3 with Codeine is an example drug. of a A) Schedule || B) Schedule II C) Schedule IV D) Schedule V
5. From the data in the table below, calculate the rate constant (k) for the degradation of the drug molecule. Pick the best answer for the rate constant. | % Drug Time (h) 93.4 1.38 85.2 3.0 75.9 6.0 A) 0.5/h B) -0.5/h C) 0.05/h D) -0.05/h 63.1 52.5 41.8 8.6 12 17
7. The concentration of drug molecule in aqueous solution drops by 10% per month when stored at room temperature. If the degradation occurs by first order, what concentration will remain if a 5 mg/mL solution of the drug is stored under these conditions for 3 months? | A) 0.35 mg/mL B) 3.6 mg/mL C) 0.4 mg/mL D) 4.0 mg/mL
Identify the single most correct choice: () a) lodine can inactivate microbial cellular proteins. ( b) Alcohols may dissolve lipids and hence possess antimicrobial activities. c) Moist heat may result in protein denaturation and hence possess antimicrobial activities. 7 d) a and c e) b and c f) a, b and c
5. Tylenol 3 with Codeine is an example of a _______________ drug.? A) Schedule II B) Schedule III C) Schedule IV D) Schedule V.
Name the desirable characteristics of chemical control agents.
Name three advantages and three disadvantages of biological treatment in comparison with physical-chemical treatment.
Which of the statements below is true about pharmaceutical or drug packaging? a.) FDA maintains tight control over regulations b.) cost is a major consideration when designing a package c.) advertising and communicating with the consumer is important for both prescription and OTC drugs. d.) shelf life is always shorter than for food so must choose material appropriately.
Explain the key concepts of a) Bioavailability b) Protein binding c) Therapeutic index
4. Which of the following explains why steroids are considered.to.be lipids? a) They contain fatty acids b) They are used as fat storage c) They are lipid soluble d) The are rich in hydrogen e) None of the above
#44(c) A patient has been monitored after coma due to over pills consumption as prescribed. A doctor decided to test the presence of dnugs which can be detected by testing samples from patient's body fluid. Propose and justify TWO (2) types of method for drug testing..

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