13) Suppose that your company has just developed a new screening test for a disease, and you are in charge of testing its validity. You decide to evaluate the test on 1200 individuals and compare the results of the new test to the gold standard. You know the prevalence of disease in your population is 20%. The screening test gave a positive result for 228 individuals. 220 of these individuals actually had the disease according to the gold standard 13a) Fill in all cells of the 2 x 2 table

MATLAB: An Introduction with Applications
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Chapter1: Starting With Matlab
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13) Suppose that your company has just developed a new screening test for a disease, and you are in
charge of testing its validity. You decide to evaluate the test on 1200 individuals and compare the
results of the new test to the gold standard. You know the prevalence of disease in your population is
20%. The screening test gave a positive result for 228 individuals. 220 of these individuals actually
had the disease according to the gold standard
13a) Fill in all cells of the 2 x 2 table
Results of
Test
Screening
Positive
Negative
Total
Gold Standard Determination of Disease
Positive
Negative
Total
13b) Calculate the sensitivity, specificity, and positive predictive value of the new screening test
13c) If this test were administered in a population with a disease prevalence of 1% instead of 20%
(note that the sensitivity and specificity of the test remain unchanged), how would this influence the
positive predictive value?
Transcribed Image Text:13) Suppose that your company has just developed a new screening test for a disease, and you are in charge of testing its validity. You decide to evaluate the test on 1200 individuals and compare the results of the new test to the gold standard. You know the prevalence of disease in your population is 20%. The screening test gave a positive result for 228 individuals. 220 of these individuals actually had the disease according to the gold standard 13a) Fill in all cells of the 2 x 2 table Results of Test Screening Positive Negative Total Gold Standard Determination of Disease Positive Negative Total 13b) Calculate the sensitivity, specificity, and positive predictive value of the new screening test 13c) If this test were administered in a population with a disease prevalence of 1% instead of 20% (note that the sensitivity and specificity of the test remain unchanged), how would this influence the positive predictive value?
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