1 The Asp residue with a pka = 6 is found in the active site of an enzyme. This residue acts as an acid catalyst. Assuming that the enzyme is stable at a wide range of PH and that the Aspartic acid residue is the only ionizable residue in the active site, please draw the curve of enzyme activity versus pH on the graph below and explain the shape of your curve. (10 points) 100 % enzyme activity 75 50 25 3 LO 5 1 7 pH 9 11
1 The Asp residue with a pka = 6 is found in the active site of an enzyme. This residue acts as an acid catalyst. Assuming that the enzyme is stable at a wide range of PH and that the Aspartic acid residue is the only ionizable residue in the active site, please draw the curve of enzyme activity versus pH on the graph below and explain the shape of your curve. (10 points) 100 % enzyme activity 75 50 25 3 LO 5 1 7 pH 9 11
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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![1 The Asp residue with a pka = 6 is found in the active site of an enzyme. This residue acts as an
acid catalyst. Assuming that the enzyme is stable at a wide range of PH and that the Aspartic acid
residue is the only ionizable residue in the active site, please draw the curve of enzyme activity
versus pH on the graph below and explain the shape of your curve. (10 points)
100
% enzyme activity
75
50
25
3
LO
5
7
pH
T
9
11](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Ff026bff6-c628-44ef-9f7e-8c5af61767da%2F42cba7fc-3293-48b8-8e3d-838820e0ce2d%2F8yjfrwp_processed.png&w=3840&q=75)
Transcribed Image Text:1 The Asp residue with a pka = 6 is found in the active site of an enzyme. This residue acts as an
acid catalyst. Assuming that the enzyme is stable at a wide range of PH and that the Aspartic acid
residue is the only ionizable residue in the active site, please draw the curve of enzyme activity
versus pH on the graph below and explain the shape of your curve. (10 points)
100
% enzyme activity
75
50
25
3
LO
5
7
pH
T
9
11
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