1- B cell clones undergo somatic hypermutation in which structure? Group of answer choices A) Thymic cortex B) Bone marrow C) Primary focus D) Germinal center dark zone   2- During T cell development, the surrogate alpha chain (pTalpha) is considered analogous to the surrogate light chains (lambda5 and VpreB) expressed during B cell development.  Which complexes do these surrogate protein chains help form in T cell and B cells, respectively? Group of answer choices A) Mature TCR and transitional B cell BCR B) Double positive thymocyte CD4/CD8 complex and mature naive B cell IgD/IgM complex C) preTCR and preBCR D) Thymic progenitor Notch receptor and early pro-B cell IL-7 receptor

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