PhysioEx Exercise 2 Activity 2-2
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Jan 9, 2024
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The Effect of Stimulus Voltage on Skeletal Muscle Contraction Reset Activity Lab Report Accessibility •
ObjectivesIntroductionPre-lab QuizExperimentPost-lab QuizReview SheetLab Report
Pre-lab Quiz Results You scored 50% by answering 2 out of 4 questions correctly. 1 Skeletal muscle fibers are innervated (stimulated) by You correctly answered: motor neurons. 2 A single action potential propagating down a motor axon results in Your answer: a single action potential and several contractile events in the muscle fibers it innervates. Correct answer: a single action potential and a single contractile event in the muscle fibers it innervates. 3 In resting skeletal muscle, calcium is stored in Your answer: the sarcomere. Correct answer: the sarcoplasmic reticulum. 4 During the latent period for an isometric contraction You correctly answered: the cellular events involved in excitation-contraction coupling occur. Experiment Results
Predict Question 1 Predict Question: As the stimulus voltage is increased from 1.0 volt up to 10 volts, what will happen to the amount of active force generated with each stimulus? Your answer: The active force will continually increase. Stop & Think Questions 1 What do you observe in the active force display when the stimulus voltage is set to 0.0, and why does this observation make sense? You correctly answered: 0.00; there was no activation of skeletal muscle fibers by this stimulus. 2 What is the lowest stimulus voltage that induces active force in the skeletal muscle? You correctly answered: threshold voltage. 3 Enter the threshold voltage for this experiment. You answered: 1 volts. 4 Enter the maximal voltage for this experiment. You answered: 8 volts. Experiment Data Voltage (volts)Voltage (v)Length (millimeters)Length (mm)Active ForcePassive ForceTotal Force 0.0750.000.000.00 0.2750.000.000.00 0.5750.000.000.00 0.6750.000.000.00 0.8750.020.000.02 0.9750.090.000.09 1.0750.150.000.15 1.1750.210.000.21
1.0750.150.000.15 1.5750.430.000.43 Voltage = 0.0 V Voltage = 0.2 V
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Voltage = 0.5 V Voltage = 0.6 V
Voltage = 0.8 V Voltage = 0.9 V
Voltage = 1.0 V Voltage = 1.1 V
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Voltage = 1.0 V Voltage = 1.5 V
Post-lab Quiz Results You scored 67% by answering 4 out of 6 questions correctly. 1 Motor unit recruitment refers to You correctly answered: an increase in the number of active muscle fibers to increase the force developed in a muscle. 2 Active tension (or force) in a skeletal muscle fiber results from You correctly answered: activation of cross bridge cycling via increased intracellular calcium levels. 3 The blank is the minimal stimulus needed to cause a depolarization of the muscle plasma membrane (sarcolemma). You correctly answered: threshold voltage. 4
By definition, the blank is the amount of stimulus required to successfully recruit all
the muscle fibers into developing active force. You correctly answered: maximal voltage. 5 Why was a maximal voltage observed in this experiment? Your answer: The maximal voltage induces the most acetylcholine release from a muscle fiber's sarcolemma (or plasma membrane). Correct answer: At the maximal voltage, all the muscle fibers contained in this muscle are depolarized and they all develop active force (that is, they were all successfully recruited). 6 A sufficiently strong electrical stimulus applied to an isolated, mounted skeletal muscle induces the development of muscle force, or muscle tension. Which of the following statements concerning this observation is true
? Your answer: As the strength of the electrical stimulus is increased, the amount of force each individual muscle fiber generates also increases. Correct answer: The electrical stimulus mimics acetylcholine release at a neuromuscular junction. Review Sheet Results 1 Describe the effect of increasing stimulus voltage on isolated skeletal muscle. Specifically, what happened to the muscle force generated with stronger electrical stimulations and why did this change occur? How well did the results compare with your prediction? Your answer: The force increased until it was at the max which was 8 volts. 2 How is this change in whole-muscle force achieved in vivo
? Your answer: It is achieved by motor neurons sending signals to the skeletal muscles to contract.
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3 What happened in the isolated skeletal muscle when the maximal voltage was applied? Your answer: The output of power reached it's max threashhold. Printable/Saveable Version Prev 1 of 1 Next ALWAYS LEARNING
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