
Concept explainers
(a)
To calculate: The number of turns of an α helix that is required to span a lipid bilayer.
Concept introduction: Lipid bilayer or phospholipid bilayer is a thin polar membrane that is made up of two layers of lipid molecules. The membrane is like flat sheets that forms continuous layers of lipid molecules. The polypeptide chain penetrate or span the lipid bilayer if it has hydrophobic side chains that contact the lipid tails and can shield its polar back bone.
(b)
To calculate: The minimum number of residues required to span a lipid bilayer.
Concept introduction: Lipid bilayer or phospholipid bilayer is a thin polar membrane that is made up of two layers of lipid molecules. The membrane is like flat sheets that forms continuous layers of lipid molecules. The polypeptide chain penetrate or span the lipid bilayer if it has hydrophobic side chains that contact the lipid tails and can shield its polar back bone.
(c)
To explain: The reason why most of the transmembrane helices contain more than the minimum number of residues.
Concept introduction: Transmembrane proteins are a type of integral membrane proteins. They span the entirety of the biological membrane in which they are permanently attached to it. The transmembrane segments of the integral membrane proteins consist of either α helix or β sheets.

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Chapter 9 Solutions
Fundamentals of Biochemistry: Life at the Molecular Level
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- 3. Which one of the compounds below is the major product formed by the reaction sequence shown here? CH3 + CH3NO2 NaOH H2, Ni ? nitromethane acetophenone OH OH HO HN- u x x x x Ph A HO -NH2 HO H Ph Ph Ph N- H B Ph NH2 D Earrow_forward4. Only ONE of the five compounds below can be prepared by an aldol condensation in which a single carbonyl compound is treated with base. Which one is it? To solve this problem, reverse the aldol condensation that formed each of these molecules to find out what two molecules came together to make the products. The one in which the two molecules are identical is the answer. Ph Ph ཚིག གནས ག ནཱ ཀ ན ཀནཱ A Ph H B Ph Ph H D Ph. Ph Ph E Harrow_forward5. Which one is the major organic product obtained from the following reaction sequence? First, equimolar amounts of cyclopentanone and LDA are mixed at -78°C. Then propionaldehyde (propanal) is added. Addition of aqueous acid completes the process. LDA, -78°C. 1. 2. H₂O* H A B H 0 D H H Earrow_forward
- 2. Which one is the major organic product obtained from the following reaction? NaOH, H₂O heat A B C D Earrow_forwardCH3CH2CHO + propanal PhCH2CHO 2-phenylacetaldehyde mixture of four products NaOH 10. In the crossed aldol reaction of propanal and 2-phenylacetaldehyde shown above, a mixture of four products will be formed. Which ONE of the compounds below will NOT be formed in this crossed aldol reaction? OH Ph A H OH OH Ph H B OH OH H H H Ph Ph C Ph D Earrow_forwardAn organic chemist ordered the wrong item. She wanted to obtain 1-hydroxy-2-butanone, butinstead ordered 2-hydroxybutyraldehyde. As a good biochemist, show how the organic chemistcould use biological catalysis to make her desired compound.arrow_forward
- Predict the products of aldolase catalyzing the reaction with acetone and (S)-3-hydroxybutyraldehyde.arrow_forwardA cancer patient undergoing chemotherapy is taking a protein kinase inhibitor drug. The patientis an avid marathon runner and does not want to miss his upcoming race. Is it a good idea forthis patient to attempt a marathon while on this medication? Explain why or why not.arrow_forwardShow the fate of the hydrogen on carbon-2 of glucose.arrow_forward
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