Brock Biology of Microorganisms (15th Edition)
15th Edition
ISBN: 9780134261928
Author: Michael T. Madigan, Kelly S. Bender, Daniel H. Buckley, W. Matthew Sattley, David A. Stahl
Publisher: PEARSON
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Chapter 8.6, Problem 2MQ
- Give one example each of T4 early, middle, and late proteins.
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T cells can differentiate into 5 different subsets of helper T cells. Answer the following questions for TH1 cells:
A) In general, list three unique factors that differentiate the TH1 subset from the other subsets.
B) For each of those factors identified in A, provide one specific example that applies to TH1 cells.
C) What type of pathogens are targeted by the TH1 cells?
Describe the structural features of a typical immune-globulin molecule.
Describe the structure and basic functions of the five major typesof immunoglobulins.
Chapter 8 Solutions
Brock Biology of Microorganisms (15th Edition)
Ch. 8.1 - How does a virus differ from a cell?Ch. 8.1 - Why does a virus need a host cell?Ch. 8.1 - Compared with cells, what is unusual about viral...Ch. 8.1 - Once inside a host prokaryotic cell, what are the...Ch. 8.2 - Distinguish between a capsid and a capsomere. What...Ch. 8.2 - What is the difference between a naked virus and...Ch. 8.2 - What kinds of enzymes can be found within the...Ch. 8.2 - Where does the envelope surrounding animal viruses...Ch. 8.3 - What is packaged into capsids during maturation?Ch. 8.3 - Explain the term burst size.
Ch. 8.3 - Prob. 3MQCh. 8.3 - Why does a one-step growth curve differ in shape...Ch. 8.4 - What is meant by a viral titer?Ch. 8.4 - What is a plaque-forming unit?Ch. 8.4 - What is meant by the term plating efficiency?Ch. 8.4 - Describe the events that occur on an agar plate...Ch. 8.5 - How does attachment contribute to virushost...Ch. 8.5 - Prob. 2MQCh. 8.5 - Prob. 3MQCh. 8.5 - What is required for a bacteriophage T4 virion to...Ch. 8.6 - Prob. 1MQCh. 8.6 - Give one example each of T4 early, middle, and...Ch. 8.6 - What is required to package the T4 genome into its...Ch. 8.6 - Bacteriophage T4 lacks its own RNA polymerase. How...Ch. 8.7 - What is a lysogen and what is a prophage?Ch. 8.7 - How does DNA replication in lambda differ from...Ch. 8.7 - What commits lambda to the lytic versus the...Ch. 8.7 - What enzyme is required to form a prophage, and...Ch. 8.8 - Prob. 1MQCh. 8.8 - What is the difference between a persistent and a...Ch. 8.8 - Prob. 3MQCh. 8.8 - Why can it be said that the retrovirus genome is...Ch. 8 - What causes the viral plaques that appear on a...Ch. 8 - The promoters on genes encoding early proteins in...Ch. 8 - Under some conditions, it is possible to obtain...
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- Describe the structure of immunoglobulin and the functions of the Fab and Fc portions.arrow_forwardConsider a pencil-shaped protein with two epitopes, Y (the “eraser” end) and Z (the “point” end). They are recognized by antibodies A1 and A2, respectively. Draw and label a picture showing the antibodies linking proteins into a complex that could trigger endocytosis by a macrophage.arrow_forwardDifferentiate protein complementation from supplementation? Give a concrete example in each category.arrow_forward
- (35) Human immunization with purified polysaccharide antigens generates a response that is not dependent on T-lymphocytes control. As a result switching of immunoglobulin class during immune response does not occur . Therefore,the human immune response 2 months after vaccination with purified polysaccharide involves primarily which of the following immunoglobulin classes? (A) IgA. (B) IgD. (C) IgE. (D) IgG.…arrow_forwardDo T cells bear a cell-surface receptor capable of recognizing a specific antigen?arrow_forwardThe ends of each heavy chain and light chain in an immunoglobulin make up the antigen-binding sites. The end of one of these chains is shown here. Biochemists tend to classify protein structures into four groups: mostly alpha, mostly beta, mixed alpha and beta, or neither alpha nor beta. Based on the model shown here, how would you classify this part of the immunoglobulin protein? The loopy polypeptide segments at the very top of the structure shown are the segments that actually contact the antigen. Would you expect these binding segments to be rigid or flexible?arrow_forward
- Why is the response to T-independent antigens important medically?arrow_forwardHow does the general principle of physiology apply at the molecular level in the case of immunoglobulins?arrow_forwardDifferentiate the following secondary antibodies: (a) Mice anti-human, (b) Donkey anti-human, (c) Chicken anti-human, and (d) Donkey anti-chicken.arrow_forward
- Diagram an IgG molecule and label (a) the Fc region and (b) the areas that combine with antigen.arrow_forwardT cells have to work in a partnership with an Antigen Presenting Cell (APC). Before this can occur, the APC must modify the antigen. Please discuss how this process happens and the major protein that is involved. Be detailed.arrow_forwardThe valence of an antibody that is a pentamer is: O 1) 2 O2) 4 O 3) 3 O4) 10arrow_forward
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