Brock Biology of Microorganisms (15th Edition)
15th Edition
ISBN: 9780134261928
Author: Michael T. Madigan, Kelly S. Bender, Daniel H. Buckley, W. Matthew Sattley, David A. Stahl
Publisher: PEARSON
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Textbook Question
Chapter 8.8, Problem 1CR
Why can it be said that the retrovirus genome is unique in all of biology?
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This virus does not conform to the central dogma of molecular biology. Explain the central dogma and how the virus behaves differently.
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Viruses are made up of the same biomolecules as cellular organisms (DNA, RNA, proteins, lipids, etc.), which are synthesized through enzymatic dehydration reactions from building blocks and disassembled by enzymatic hydrolysis. They infect cells and replicate themselves using resources from the host cells. Scientists discovered a previously unknown strain of virus in the tropical Pacific Ocean and it can infect higher-order eukaryotes. Initial analysis revealed that the virus is mainly composed of nucleic acids, proteins, and lipids. Chemical analysis after complete hydrolysis revealed the following building blocks (by weight):
Chemical components
Nucleosides
Amino acids
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Percentage by weight
20
30
50
Analysis of percentages of nucleosides yielded the following results (by molar ratio):
Nucleosides
A
G
T
C
U
Percentage by mole
19
29
19
29
4
Which of the following events mostly involves hydrolysis reaction after the virus infects…
Which of the following self-replicating biological agents carries only one polynucleotide chain as its genetic material, does not code for any proteins, and does not have any nucleocapsid?
the RNA virusoid known as hepatitis delta virusoid
the single-stranded RNA virus known as human immunodeficiency virus
the double-stranded RNA virus known as rotavirus
the double-stranded DNA virus known as pandoravirus
the RNA viroid known as citrus exocortis viroid
The human precancerous disorder known as xeroderma pigmentosum is caused by which of the following mutagenic conditions?
thymine dimers
demethylation
deacetylation
depurination
deamination
7. Who discovered that DNA synthesis in the intact chromosomes of rapidly-growing bacterial cells is continuous on the leading strand, but discontinuous on the lagging strand?
Rosalind Franklin and Maurice Wilkins
Matthew Meselson and Franklin Stahl
Erwin Chargaff and Arthur Kornberg
Reiji Okazaki and Tuneko Okazaki
James Watson and…
Chapter 8 Solutions
Brock Biology of Microorganisms (15th Edition)
Ch. 8.1 - How does a virus differ from a cell?Ch. 8.1 - Why does a virus need a host cell?Ch. 8.1 - Compared with cells, what is unusual about viral...Ch. 8.1 - Once inside a host prokaryotic cell, what are the...Ch. 8.2 - Distinguish between a capsid and a capsomere. What...Ch. 8.2 - What is the difference between a naked virus and...Ch. 8.2 - What kinds of enzymes can be found within the...Ch. 8.2 - Where does the envelope surrounding animal viruses...Ch. 8.3 - What is packaged into capsids during maturation?Ch. 8.3 - Explain the term burst size.
Ch. 8.3 - Prob. 3MQCh. 8.3 - Why does a one-step growth curve differ in shape...Ch. 8.4 - What is meant by a viral titer?Ch. 8.4 - What is a plaque-forming unit?Ch. 8.4 - What is meant by the term plating efficiency?Ch. 8.4 - Describe the events that occur on an agar plate...Ch. 8.5 - How does attachment contribute to virushost...Ch. 8.5 - Prob. 2MQCh. 8.5 - Prob. 3MQCh. 8.5 - What is required for a bacteriophage T4 virion to...Ch. 8.6 - Prob. 1MQCh. 8.6 - Give one example each of T4 early, middle, and...Ch. 8.6 - What is required to package the T4 genome into its...Ch. 8.6 - Bacteriophage T4 lacks its own RNA polymerase. How...Ch. 8.7 - What is a lysogen and what is a prophage?Ch. 8.7 - How does DNA replication in lambda differ from...Ch. 8.7 - What commits lambda to the lytic versus the...Ch. 8.7 - What enzyme is required to form a prophage, and...Ch. 8.8 - Prob. 1MQCh. 8.8 - What is the difference between a persistent and a...Ch. 8.8 - Prob. 3MQCh. 8.8 - Why can it be said that the retrovirus genome is...Ch. 8 - What causes the viral plaques that appear on a...Ch. 8 - The promoters on genes encoding early proteins in...Ch. 8 - Under some conditions, it is possible to obtain...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- why testing known inhibitors such as the HIV-1 protease inhibitors nelfinavir and atazanavir used in this experiment, is beneficial for creation of new antiviral drugs. Is it due to conserved viral DNA or something else entirely? nature.com/articles/s41467-021-20900-6arrow_forwardAs a general rule, viruses are not considered to be alive based on several reasons. One such reason is that some viruses use RNA as their genetic material instead of DNA. Which of the five biological themes does this violate? Briefly explain why.arrow_forwardWhat does a bacteriophage accomplish with lysogeny? O 1) it allows the bacteriophage to destroy the host cell's DNA. 2) it enables the bacteriophage to take over the cell. O 3) it speeds up the viral infection cycle. 4) it allows the bacteriophage to infect cells it would not normally infect. O 5) the genetic material of the bacteriophage can be passed on to future generations of infected cells.arrow_forward
- You are a virologist studying a newly isolated viral strain and have sequenced its genome. You find that the genome contains 25% A, 55% G, 20% C, and 10% U. Which of the following conclusions is likely correct? This is a single-stranded RNA virus This is a single-stranded DNA virus This is a double-stranded RNA virus This is a double-stranded DNA virus No conclusions can be drawn from this informationarrow_forwardWhich of the following models best depicts how the genetic information in a retrovirus is eventually translated into proteins? A) DNA in the retrovirus → RNA in the host cell → Proteins B) RNA in the retrovirus → DNA in the host cell → RNA in the host cell → Proteins C) RNA in the retrovirus → mRNA in the host cell → Proteins D) DNA in the retrovirus → mRNA in the host cell → Proteinsarrow_forwardWhat evolutionary advantage would a retrovirus gain by having the ability to regulate the sites of splicing of its RNA?arrow_forward
- Why can’t RNA viruses have a big genome? Why do RNA viruses have a high mutation rate?arrow_forwardWhich biological system contains a protein nucleocapsid surrounding 2 antiparallel polynucleotide strands (held together by hydrogen bonds), with deoxyribose sugars, but no ribose sugars? a single-stranded RNA viroid (like avocado sun blotch viroid) a double-stranded RNA virus (like the reovirus family) a single-stranded DNA virus (like fX174 virus of E. coli) a double-stranded DNA virus (like the smallpox virus) a single-stranded RNA virus (like tobacco mosaic virus)arrow_forwardWhich of the following is a known characteristic that can lead to genetic changes in some viruses? Operons in the viral genome can undergo homologous recombination, leading to genetic rearrangements. Reassortment of segmented genomes can occur if a host cell is co-infected with two different viral strains. RNA polymerases used in replication of the viral genome have proofreading capability. Environmental conditions can trigger the SOS response, which triggers mutations in the viral genome.arrow_forward
- What is the purpose of reverse transcriptase in retroviruses? It translates viral RNA into proteins. It converts host cell RNA into viral DNA. It uses viral RNA as a template for DNA synthesis. It uses viral RNA as a template for making more viral RNA strands.arrow_forwardWhy is HIV called a retrovirus?arrow_forwardSome retroviruses that have a wide host range have been developed for use in treatment of diseases or syndromes. These viruses do not result in a productive infection because they lack critical genes for viral replication, but they do carry DNA sequences that allow them to be packaged into infectious particles. Once in the host cell the viral DNA is released and integrates into the cell's genome. The advantage to this strategy is that the delivery of the DNA is very efficient. What is one possible problem of using a virus that can integrate into the human nuclear genome? Multiple Choice The virus carries genes that will interfere with host cell activities. The viral DNA sequences could still cause a disease. Since the viral DNA sequences no longer contain essential genes for viral replication the host cell may not be able to replicate either. The integration could disrupt an essential gene or genes.arrow_forward
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What Is A Virus ? ; Author: Peekaboo Kidz;https://www.youtube.com/watch?v=YS7vsBgWszI;License: Standard YouTube License, CC-BY