Genetics: From Genes to Genomes, 5th edition
5th Edition
ISBN: 9780073525310
Author: Leland H. Hartwell, Michael L. Goldberg, Janice A. Fischer, Leroy Hood, Charles F. Aquadro
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 8, Problem 8P
The amino acid sequence of part of a protein has been determined:
N…Gly Ala Pro Arg Lys…C
A mutation has been induced in the gene encoding this protein using the mutagen proflavin. The resulting mutant protein can be purified and its amino acid sequence determined. The amino acid sequence of the mutant protein is exactly the same as the amino acid sequence of the wild-type protein from the N terminus of the protein to the glycine in the preceding sequence. Starting with this glycine, the sequence of amino acids is changed to the following:
N…Gly His Gln Gly Lys…C
Using the amino acid sequences, one can determine the sequence of 14
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Chapter 8 Solutions
Genetics: From Genes to Genomes, 5th edition
Ch. 8 - For each of the terms in the left column, choose...Ch. 8 - Match the hypothesis from the left column to the...Ch. 8 - How would the artificial mRNA 5GUGUGUGU . . . 3 be...Ch. 8 - An example of a portion of the T4 rIIB gene in...Ch. 8 - Consider Crick and Brenners experiments in Fig....Ch. 8 - The HbSsickle-cell allele of the human -globin...Ch. 8 - The following diagram describes the mRNA sequence...Ch. 8 - The amino acid sequence of part of a protein has...Ch. 8 - The results shown in Fig. 8.5 on p. 260 may have...Ch. 8 - Identify all the amino acid-specifying codons in...
Ch. 8 - Before the technology existed to synthesize RNA...Ch. 8 - A particular protein has the amino acid sequence...Ch. 8 - Prob. 13PCh. 8 - How many possible open reading frames frames...Ch. 8 - a. In Fig. 8.3 on p. 257, the physical map the...Ch. 8 - Charles Yanofsky isolated many different trpA-...Ch. 8 - Remembering that the wobble base of the tRNA is...Ch. 8 - The sequence of a segment of mRNA, beginning with...Ch. 8 - You identify a proflavin-generated allele of a...Ch. 8 - In certain bacterial species, pyrrolysine Pyl,...Ch. 8 - Describe the steps in transcription that require...Ch. 8 - Chapters 6 and 7 explained that mistakes made by...Ch. 8 - The coding sequence for gene F is read from left...Ch. 8 - If you mixed the mRNA of a human gene with the...Ch. 8 - Describe the steps in translation that require...Ch. 8 - Locate as accurately as possible the listed items...Ch. 8 - Concerning the figure for Problem 26: a. Which...Ch. 8 - In prokaryotes, a search for genes in a DNA...Ch. 8 - The yeast gene encoding a protein found in the...Ch. 8 - The sequence of a complete eukaryotic gene...Ch. 8 - Using recombinant DNA techniques which will be...Ch. 8 - a. The genetic code table shown in Fig. 8.2 on p....Ch. 8 - Arrange the following list of eukaryotic gene...Ch. 8 - Concerning the list of eukaryotic gene elements in...Ch. 8 - The human gene for 2 lens crystallin has the...Ch. 8 - Do you think each of the following types of...Ch. 8 - Null mutations are valuable genetic resources...Ch. 8 - The following is a list of mutations that have...Ch. 8 - Considering further the mutations described in...Ch. 8 - When 1 million cells of a culture of haploid yeast...Ch. 8 - Why is a nonsense suppressor tRNATyr, even though...Ch. 8 - Prob. 42PCh. 8 - You are studying mutations in a bacterial gene...Ch. 8 - Another class of suppressor mutations, not...Ch. 8 - Yet another class of suppressor mutations not...Ch. 8 - There is at least one nonsense suppressing tRNA is...Ch. 8 - Prob. 47PCh. 8 - Brenners m mutant phages m1 m6 described in Fig....
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