Smoking Cessation in HIV Patients In a 2018 study reported in The Lancet, Mercie et al. investigated the efficacy and safety of varenicline for smoking cessation in people living with HIV. The study was a randomized, double-blind, placebo-controlled trial. Of the 123 subjects treated with varenicline, 18 abstained from smoking for the entire 48-week study period. Of the 124 subjects assigned to the placebo group, 8 abstained from smoking for the entire study period. a. Find the sample percentage of subjects in each group who abstained from smoking for the entire study period. b. Determine whether varenicline is effective in reducing smoking among HIV patients. Note that this means we should test if the proportion of the varenicline group who abstained from smoking for the entire study period is significantly greater than that of the placebo group. Use a significance level of 0.05.
Smoking Cessation in HIV Patients In a 2018 study reported in The Lancet, Mercie et al. investigated the efficacy and safety of varenicline for smoking cessation in people living with HIV. The study was a randomized, double-blind, placebo-controlled trial. Of the 123 subjects treated with varenicline, 18 abstained from smoking for the entire 48-week study period. Of the 124 subjects assigned to the placebo group, 8 abstained from smoking for the entire study period. a. Find the sample percentage of subjects in each group who abstained from smoking for the entire study period. b. Determine whether varenicline is effective in reducing smoking among HIV patients. Note that this means we should test if the proportion of the varenicline group who abstained from smoking for the entire study period is significantly greater than that of the placebo group. Use a significance level of 0.05.
Solution Summary: The author calculates the sample percentage of subjects for varenicline and placebo group, and determines whether it is effective in reducing smoking among HIV patients.
Smoking Cessation in HIV Patients In a 2018 study reported in The Lancet, Mercie et al. investigated the efficacy and safety of varenicline for smoking cessation in people living with HIV. The study was a randomized, double-blind, placebo-controlled trial. Of the 123 subjects treated with varenicline, 18 abstained from smoking for the entire 48-week study period. Of the 124 subjects assigned to the placebo group, 8 abstained from smoking for the entire study period.
a. Find the sample percentage of subjects in each group who abstained from smoking for the entire study period.
b. Determine whether varenicline is effective in reducing smoking among HIV patients. Note that this means we should test if the proportion of the varenicline group who abstained from smoking for the entire study period is significantly greater than that of the placebo group. Use a significance level of
0.05.
Throughout, A, B, (An, n≥ 1), and (Bn, n≥ 1) are subsets of 2.
1. Show that
AAB (ANB) U (BA) = (AUB) (AB),
Α' Δ Β = Α Δ Β,
{A₁ U A2} A {B₁ U B2) C (A1 A B₁}U{A2 A B2).
16. Show that, if X and Y are independent random variables, such that E|X|< ∞,
and B is an arbitrary Borel set, then
EXI{Y B} = EX P(YE B).
Proposition 1.1 Suppose that X1, X2,... are random variables. The following
quantities are random variables:
(a) max{X1, X2) and min(X1, X2);
(b) sup, Xn and inf, Xn;
(c) lim sup∞ X
and lim inf∞ Xn-
(d) If Xn(w) converges for (almost) every w as n→ ∞, then lim-
random variable.
→ Xn is a
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