ND STONY BROOK UNIVERSITY LOOSELEAF GENETICS: FROM GENES TO GENOMES
6th Edition
ISBN: 9781260406092
Author: HARTWELL, Leland, HOOD, Leroy, Goldberg, Michael
Publisher: Mcgraw-hill Education/stony Brook University
expand_more
expand_more
format_list_bulleted
Textbook Question
Chapter 8, Problem 52P
Another class of suppressor mutations, not described in the chapter, are mutations that suppress missense mutations.
a. | Why would bacterial strains carrying such missense suppressor mutations generally grow more slowly than strains carrying nonsense suppressor mutations? |
b. | What other kinds of mutations can you imagine in genes encoding components needed for gene expression that would suppress a missense mutation in a protein-coding gene? |
Expert Solution & Answer

Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
buatkan judul skripsi tentang parasitologi yang sedang trendinh
Dental assistant
O Macmillan Learning
Glu-His-Trp-Ser-Gly-Leu-Arg-Pro-Gly
The pKa values for the peptide's side chains, terminal amino groups, and carboxyl groups are provided in the table.
Amino acid Amino pKa Carboxyl pKa Side-chain pKa
glutamate
9.60
2.34
histidine
9.17
1.82
4.25
6.00
tryptophan
9.39
2.38
serine
9.15
2.21
glycine
9.60
2.34
leucine
9.60
2.36
arginine
9.04
2.17
12.48
proline
10.96
1.99
Calculate the net charge of the molecule at pH 3.
net charge at pH 3:
Calculate the net charge of the molecule at pH 8.
net charge at pH 8:
Calculate the net charge of the molecule at pH 11.
net charge at pH 11:
Estimate the isoelectric point (pl) for this peptide.
pl:
Chapter 8 Solutions
ND STONY BROOK UNIVERSITY LOOSELEAF GENETICS: FROM GENES TO GENOMES
Ch. 8 - For each of the terms in the left column, choose...Ch. 8 - Match the hypothesis from the left column to the...Ch. 8 - How would the artificial mRNA 5GUGUGUGU . . . 3 be...Ch. 8 - An example of a portion of the T4 rIIB gene in...Ch. 8 - Consider Crick and Brenners experiments in Fig....Ch. 8 - The HbSsickle-cell allele of the human -globin...Ch. 8 - The following diagram describes the mRNA sequence...Ch. 8 - The amino acid sequence of part of a protein has...Ch. 8 - The results shown in Fig. 8.5 may have struck you...Ch. 8 - Identify all the amino acid-specifying codons in...
Ch. 8 - Before the technology existed to synthesize RNA...Ch. 8 - A particular protein has the amino acid sequence...Ch. 8 - How many possible open reading frames frames...Ch. 8 - Prob. 14PCh. 8 - Charles Yanofsky isolated many different trpA-...Ch. 8 - The sequence of a segment of mRNA, beginning with...Ch. 8 - You identify a proflavin-generated allele of a...Ch. 8 - Using recombinant DNA techniques which will be...Ch. 8 - Describe the steps in transcription that require...Ch. 8 - Chapters 6 and 7 explained that mistakes made by...Ch. 8 - The coding sequence for gene F is read from left...Ch. 8 - If you mixed the mRNA of a human gene with the...Ch. 8 - Prob. 23PCh. 8 - The Drosophila gene Dscam1 encodes proteins on the...Ch. 8 - Describe the steps in translation that require...Ch. 8 - Locate as accurately as possible the listed items...Ch. 8 - Concerning the figure for Problem 26: a. Which...Ch. 8 - a. Can a tRNA exist that has the anticodon...Ch. 8 - For parts a and b of Problem 28, consider the DNA...Ch. 8 - Remembering that the wobble base of the tRNA is...Ch. 8 - Prob. 31PCh. 8 - The yeast gene encoding a protein found in the...Ch. 8 - The sequence of a complete eukaryotic gene...Ch. 8 - Arrange the following list of eukaryotic gene...Ch. 8 - Prob. 35PCh. 8 - The human gene for 2 lens crystallin has the...Ch. 8 - In prokaryotes, a search for genes in a DNA...Ch. 8 - a. The genetic code table shown in Fig. 8.2...Ch. 8 - a. Very few if any eukaryotic genes contain tracts...Ch. 8 - Explain how differences in the initiation of...Ch. 8 - Do you think each of the following types of...Ch. 8 - Null mutations are valuable genetic resources...Ch. 8 - The following is a list of mutations that have...Ch. 8 - Considering further the mutations described in...Ch. 8 - Adermatoglyphia described previously in Problem 18...Ch. 8 - Prob. 46PCh. 8 - You learned in Problem 21 in Chapter 7 that the...Ch. 8 - When 1 million cells of a culture of haploid yeast...Ch. 8 - Why is a nonsense suppressor tRNATyr, even though...Ch. 8 - A mutant B. adonis bacterium has a nonsense...Ch. 8 - You are studying mutations in a bacterial gene...Ch. 8 - Another class of suppressor mutations, not...Ch. 8 - Yet another class of suppressor mutations not...Ch. 8 - At least one nonsense suppressing tRNA is known...Ch. 8 - An investigator was interested in studying UAG...Ch. 8 - Prob. 56PCh. 8 - In certain bacterial species, pyrrolysine Pyl,...Ch. 8 - Canavanine is an amino acid similar to arginine...
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Biology Questionarrow_forwardThis entire structure (Pinus pollen cone) using lifecycle terminology is called what?arrow_forwardThis entire structure using lifecycle terminology is called what? megastrobilus microstrobilus megasporophyll microsporophyll microsporangium megasporangium none of thesearrow_forward
- How much protein should Sarah add to her diet if she gets pregnant? Sarah's protein requirements during pregnancy would be higher. See Hint B2. During calculations, use numbers rounded to the first decimal place. In your answer, round the number of grams to the nearest whole number. _______ g ?arrow_forwardC MasteringHealth MasteringNu X session.healthandnutrition-mastering.pearson.com/myct/itemView?assignment ProblemID=17396422&attemptNo=1&offset=prevarrow_forwardMost people, even those who exercise regularly at low to average intensity (1 hour at the gym or a 2- to 3-mile walk several times per week), do not need an increased protein intake. What would be the protein needs of a man named Josh who exercises moderately and is the same age and size as Wayne? Josh is 5 ft, 8 in tall and weighs 183 lb. Round the number of grams to the nearest whole number. During calculations, use numbers rounded to the first decimal place. Because protein requirement is a range, please enter two numbers: lower and upper range values, respectively. Separate the lower and upper range values, in that order, by a comma. ___, ___ g ?arrow_forwardC MasteringHealth MasteringNu X session.healthandnutrition-mastering.pearson.com/myct/itemView?assignment ProblemID=17396422&attemptNo=1&offset=prevarrow_forwardIf left untreated, most HIV-infected individuals will develop AIDS. Current treatments are focused on highlyactive antiretroviral therapy (HAART). HAART usually consists of an orally delivered drug cocktail containingtwo different reverse transcriptase inhibitors and one other drug, such as a protease inhibitor. Question: Develop a pharmacokinetic model of HAART treatment. Consider all 3 drugs. Make sure to include adiagram that illustrates your thinking, state all assumptions, and define your variables. Whatparameters would you need to know to find the concentration of drug in the plasma? In the T cells?(You do not need to write out or solve any equations.)arrow_forwardnot use ai pleseaarrow_forward(A) 25 20 20 15 NPP (Mg C/ha/yr) 10 10 5 0 0 2,000 4,000 6,000 ECOLOGY 4e, Figure 20.11 (Part 1) 2017 Sinauer Associates, Inc. Average annual precipitation (mm) 8,000arrow_forwardexplain the cascade of events (starting with relaxing trade winds) that occurs during El Niño in the eastern Pacific (off the coasts of California/North America and Peru/South America) and which lead to food-chain collapse - start with changes in the physical/oceanographic conditions, andthen systematically describe the cascading effects at each level of the food chain -arrow_forward3) Which statement(s) about the Pacific Decadal Oscillation (PDO) is/are TRUE? CIRCLE ALL THAT APPLY. A. It is a major driver of salmon populations in the Pacific B. It affects sea surface temperatures in the eastern Pacific C. Its cycles typically do not last as long as those of ENSO D. Evidence that it has occurred over many centuries has been gathered from tree ring dataarrow_forwardarrow_back_iosSEE MORE QUESTIONSarrow_forward_iosRecommended textbooks for you
- Human Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage LearningBiology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStaxBiology (MindTap Course List)BiologyISBN:9781337392938Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. BergPublisher:Cengage Learning
- Biology Today and Tomorrow without Physiology (Mi...BiologyISBN:9781305117396Author:Cecie Starr, Christine Evers, Lisa StarrPublisher:Cengage LearningBiology: The Dynamic Science (MindTap Course List)BiologyISBN:9781305389892Author:Peter J. Russell, Paul E. Hertz, Beverly McMillanPublisher:Cengage LearningAnatomy & PhysiologyBiologyISBN:9781938168130Author:Kelly A. Young, James A. Wise, Peter DeSaix, Dean H. Kruse, Brandon Poe, Eddie Johnson, Jody E. Johnson, Oksana Korol, J. Gordon Betts, Mark WomblePublisher:OpenStax College
Human Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage LearningBiology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStaxBiology (MindTap Course List)BiologyISBN:9781337392938Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. BergPublisher:Cengage LearningBiology Today and Tomorrow without Physiology (Mi...BiologyISBN:9781305117396Author:Cecie Starr, Christine Evers, Lisa StarrPublisher:Cengage LearningBiology: The Dynamic Science (MindTap Course List)BiologyISBN:9781305389892Author:Peter J. Russell, Paul E. Hertz, Beverly McMillanPublisher:Cengage LearningAnatomy & PhysiologyBiologyISBN:9781938168130Author:Kelly A. Young, James A. Wise, Peter DeSaix, Dean H. Kruse, Brandon Poe, Eddie Johnson, Jody E. Johnson, Oksana Korol, J. Gordon Betts, Mark WomblePublisher:OpenStax College
What are Mutations and what are the different types of Mutations?; Author: Science ABC;https://www.youtube.com/watch?v=I16YlE8qTBU;License: Standard youtube license