BIOLOGY
5th Edition
ISBN: 9781265202859
Author: BROOKER
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Chapter 7, Problem 2CQ
What causes the rotation of the γ subunit of ATP synthase? How does this rotation promote ATP synthesis?
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What causes the c subunits of ATP synthase to rotate? What determines the direction of rotation?
What causes the rotation of the γ subunit of the ATP synthase? Howdoes this rotation promote ATP synthesis?
Discuss the composition of the transition state for the formation of ATP by ATP Synthase.
a) Where is the active site for this enzyme located?
b) How are the amino acid side chains from the α and β subunits of ATP Synthase involved?
c) Discuss the importance of Mg+2 in the mechanism of this enzyme.
Chapter 7 Solutions
BIOLOGY
Ch. 7.2 - Core Skill: Connections Look ahead to Table 45.1....Ch. 7.2 - Which organic molecules donate a phosphate group...Ch. 7.2 - Prob. 2CSCh. 7.4 - Prob. 1CCCh. 7.5 - Explain the meaning of the name cytochrome...Ch. 7.6 - Prob. 1CCCh. 7.6 - Prob. 1CSCh. 7.6 - Prob. 1EQCh. 7.6 - CoreSKILL In the experiment of Figure 7.13, what...Ch. 7.6 - Prob. 3EQ
Ch. 7.7 - Prob. 1CCCh. 7 - Which of the following pathways occurs in the...Ch. 7 - Prob. 2TYCh. 7 - Prob. 3TYCh. 7 - Which organic molecule supplies a two-carbon group...Ch. 7 - The ability to diagnose tumors using...Ch. 7 - Prob. 6TYCh. 7 - Certain drugs, which are called ionophores, cause...Ch. 7 - Prob. 8TYCh. 7 - Prob. 9TYCh. 7 - Prob. 10TYCh. 7 - Prob. 1CQCh. 7 - What causes the rotation of the subunit of ATP...Ch. 7 - Core Concept: Energy and Matter How is glucose...Ch. 7 - Discuss the advantages and disadvantages of...Ch. 7 - Prob. 2COQ
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- According to Paul Boyer, the mechanism of ATP synthesis involves the rotation of the y subunit which in turn causes sequential conformation changes in the aß assemblies. Explain the steps of ATP synthesis according to this mechanism.arrow_forwardHow do the ATP mass action ratio and the IF1 protein regulate ATP synthesis?arrow_forwardDescribe the conformational changes (including substrates that bind to the different conformations) that occur in the F1 domain of ATP Synthase that result from protons flowing through the Fo domain down their concentration gradient:arrow_forward
- Why might the atpS mutant grow so slowly?arrow_forwardIf an ATP Synthase complex had 16 c-subunits in the c-ring, how many ATPs will be made from a single rotation?arrow_forwardWhat steps in glycolysis generate substrate-level phosphorylation, and how many ATP molecules are generated in this way in this pathway? How does the generation of ATP by substrate-level phosphorylation differ from ATP generation by oxidative phosphorylation?arrow_forward
- In the Cori cycle, the lactate product of glycolysis in muscle is transformedback into glucose by the liver. (a) List the enzymes involved in the lactate → glucose pathway. (b) What is the net gain/loss of ATP for one round of the Cori cycle (glucose → lactate → glucose)?arrow_forwardIf actively respiring mitochondria are exposed to an inhibitor of ATP-ADP translocase, the electrontransport chain ceases to operate. Why?arrow_forwardArrange the sequence of events in Oxidative Phosphorylation. (1-5) As the H+ ions move through the ATP synthase it'll provide the power to make the ATP synthase to turn. As it turns, a phosphate group is added to an ADP, forming a proton gradient-energy as ATP. With the help of a channel protein called ATP synthase, these H* ions are transferred back to the matrix. The electrons are passed to another electron carrier called cytochrome C (cyt C), which carries the = electrons to enzyme complex IV. Here, the last batch of H* ions are pumped into the intermembrane space. Enzyme complexes I and Il then transport the electrons through ubiquinone (Q), a mobile electron carrier. Q is reduced to QH, in the process and delivers the electrons to enzyme complex III. As this happens, more H* ions are pumped into the intermembrane space. The NADH and FADH2 produced from the previous stages of cellular respiration bring electrons across the transport chain to initiate the oxidative phosphorylation.arrow_forward
- How do the P/O ratios for NADH differ in ATP synthases that contain 10 and 15 c subunits?arrow_forwardWhat is the compound that is phosphorylated for ATP formation? What is the resulting compound when ATP liberates energy?arrow_forward20.12 Classify the enzyme that catalyzes each of the following reactions: |3| a. CH3-C-COO + CO2 + ATP OOC-CH2-C-COO + ADP + P; + H b. CH3-CH2-OH + NAD* CH3-C-H + NADH + H*arrow_forward
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