Biology: The Dynamic Science (MindTap Course List)
Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN: 9781305389892
Author: Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher: Cengage Learning
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Chapter 50.5, Problem 3SB
Summary Introduction

To review:

The activation state of CED-9 (Cell death abnormality gene 9) plays a crucial role in apoptosis.

Introduction:

Apoptosis is also called programmed cell death. This type of cell death occurs orderly, which involves the cell shrinkage, and nuclear and chromosomal fragmentation leading to cell death. It helps in the removal of cancerous and infected cells from the body.

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Draw a rough sketch of the control and experimental data using a normal dose/response curve plot: i.e. % of total bound ligand vs. concentration. Indicate Kd and Bmax on this sketch. You don’t need to use exact numbers, but the relative proportions should be close
Name something that could be happening to glutamate transporters that could have this effect on glutamate transport (i.e. the difference in glutamate transporters between control and experimental conditions). (Bonus: if you can also guess what the experimental condition is).
a. For the control condition, calculate Kd. Include units and show your work. b. For the control condition, calculate Bmax. Include units and show your work.  c. For the experimental condition, calculate Kd. Include units and show your work. For the experimental condition, calculate Bmax. Include units and show your work.
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