Genetics: From Genes to Genomes, 5th edition
Genetics: From Genes to Genomes, 5th edition
5th Edition
ISBN: 9780073525310
Author: Leland H. Hartwell, Michael L. Goldberg, Janice A. Fischer, Leroy Hood, Charles F. Aquadro
Publisher: McGraw-Hill Education
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Chapter 5, Problem 28P

a. In Drosophila, crosses between F1 heterozygotes of the form A b / a B always yield the same ratio of phenotypes in the F2 progeny regardless of the distance between the two genes (assuming complete dominance for both autosomal genes). What is this ratio? Would this also be the case if the F1 heterozygotes were A B / a b? (Hint: Remember that in Drosophila, recombination does not take place during spermatogenesis.)

b. If you intercrossed F1 heterozygotes of the form A b / a B in mice, the phenotypic ratio among the F2 progeny would vary with the map distance between the two genes. Is there a simple way to estimate the map distance based on the frequencies of the F2 phenotypes, assuming rates of recombination are equal in males and females? Could you estimate map distances in the same way if the mouse F1 heterozygotes were A B / a b?

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Chapter 5 Solutions

Genetics: From Genes to Genomes, 5th edition

Ch. 5 - Albino rabbits lacking pigment are homozygous for...Ch. 5 - In corn, the allele A allows the deposition of...Ch. 5 - If the a and b loci are 40 cM apart and an AA BB...Ch. 5 - Write the number of different kinds of phenotypes,...Ch. 5 - A DNA variant has been found linked to a rare...Ch. 5 - Figure 5.7a on p. 134 shows chromosomes during...Ch. 5 - Figure 5.7b shows bivalents in mouse primary...Ch. 5 - Cinnabar eyes cn and reduced bristles rd are...Ch. 5 - In Drosophila, the autosomal recessive dp allele...Ch. 5 - From a series of two-point crosses, the following...Ch. 5 - Map distances were determined for four different...Ch. 5 - In the tubular flowers of foxgloves, wild-type...Ch. 5 - In Drosophila, the recessive allele mb of one gene...Ch. 5 - A snapdragon with pink petals, black anthers, and...Ch. 5 - In Drosophila, three autosomal genes have the...Ch. 5 - Drosophila females heterozygous for each of three...Ch. 5 - Male Drosophila expressing the autosomal recessive...Ch. 5 - a. In Drosophila, crosses between F1 heterozygotes...Ch. 5 - A true-breeding strain of Virginia tobacco has...Ch. 5 - Prob. 30PCh. 5 - The following list of four Drosophila mutations...Ch. 5 - Do the data that Mendel obtained fit his...Ch. 5 - Two genes control color in corn snakes as follows:...Ch. 5 - A mouse from a true-breeding population with...Ch. 5 - Neurospora of genotype a c are crossed with...Ch. 5 - A cross was performed between one haploid strain...Ch. 5 - A cross was performed between a yeast strain that...Ch. 5 - Two crosses were made in Neurospora involving the...Ch. 5 - Indicate the percentage of tetrads that would have...Ch. 5 - Prob. 42PCh. 5 - Prob. 43PCh. 5 - Prob. 44PCh. 5 - a. In ordered tetrad analysis, what is the maximum...Ch. 5 - A research group has selected three independent...Ch. 5 - A single yeast cell placed on a solid agar will...Ch. 5 - Prob. 48PCh. 5 - In Drosophila, the yellow y gene is near the end...Ch. 5 - Neurofibromas are tumors of the skin that can...Ch. 5 - Two important methods for understanding the...
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