LIFE: THE SCIENCE OF BIOLOGY
11th Edition
ISBN: 9781319145125
Author: Sadava
Publisher: MAC HIGHER
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Chapter 49.3, Problem 2R
Summary Introduction
To review:
The reason for using digitalis drug to treat patients with a weakened heart by increasing the concentration of calcium ions in the cardiac muscle cells.
Introduction:
Digitalis is a drug used to treat heart disease. It is obtained from the plant species Digitalis purpurea, commonly known as foxglove. This plant contains phytochemicals such as cardiac glycosides, digitoxin, and digitonin. This helps to control the heart rate.
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Students have asked these similar questions
a. What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent.
b. What will happen to elimination of the drug in the previous question if the system is saturated? explain and show any math involved
If you wanted to reduce the difference between peak and trough levels that occur with repeated administration of a drug, how would you adjust the dose and dose interval without changing the plateau concentration (plateau is the average of peak and trough levels)? Select your answers for both dose and interval. Hint: It may be helpful to think about this problem using an example such as food. How would you eat if you wanted to maintain very steady hunger/satiety levels without changing your total caloric intake?
Options:
A. Dose; Increase dose
B. Dose; Decrease dose
C. Dose; Do not change dose
D. Interval; Increase the interval between doses (give the drug less frequently)
E. Interval; Decrease the interval between doses (give the drug more frequently)
F. Interval; Do not change the interval
What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent. Show the math
Chapter 49 Solutions
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