Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN: 9781305251052
Author: Michael Cummings
Publisher: Cengage Learning
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Textbook Question
Chapter 4.7, Problem 1EG
Did the fact that Prince Albert and Queen Victoria were first cousins have anything to do with the fact that she carried the allele for hemophilia? Why or why not?
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Queen Victoria had 1 (Leopold) out of four male offspring with hemophilia. What was the probability of this scenario?
Hemophilia is known as "The royal disease" because many of the European royal families had members afflicted with it. A really famous case was Queen Victoria's (1819-1901) descendants who spread the disease across Europe, from Spain to Russia.
You can see the pedigree of Queen Victoria's family here:Hemophilia is an X-linked recessive disease. With the information provided, please answer the following questions:
Fred has blood type AB. His wife Sandra is blood type O. Sandra has baby Joe who is blood type A. Could Fred be the father?
If someone was described as having homozygous Type B blood, what would be there genotype?
Chapter 4 Solutions
Human Heredity: Principles and Issues (MindTap Course List)
Ch. 4.3 - Does a pedigree drawn from the available...Ch. 4.3 - Prob. 2EGCh. 4.7 - Did the fact that Prince Albert and Queen Victoria...Ch. 4.7 - Which members of the pedigree could have been...Ch. 4 - Pedigree analysis is a fundamental tool for...Ch. 4 - Pedigree analysis is a fundamental tool for...Ch. 4 - Pedigree analysis is a fundamental tool for...Ch. 4 - Pedigree Analysis Is a Basic Method in Human...Ch. 4 - Pedigree Analysis Is a Basic Method in Human...Ch. 4 - Pedigree Analysis Is a Basic Method in Human...
Ch. 4 - Pedigree Analysis Is a Basic Method in Human...Ch. 4 - Analysis of Autosomal Recessive and Dominant...Ch. 4 - Analysis of Autosomal Recessive and Dominant...Ch. 4 - Use the following information to respond to the...Ch. 4 - Analysis of Autosomal Recessive and Dominant...Ch. 4 - Analysis of Autosomal Recessive and Dominant...Ch. 4 - A proband female with an unidentified disease...Ch. 4 - Analysis of Autosomal Recessive and Dominant...Ch. 4 - Prob. 12QPCh. 4 - Analysis of Autosomal Recessive and Dominant...Ch. 4 - Analysis of Autosomal Recessive and Dominant...Ch. 4 - Analysis of X-Linked Dominant and Recessive Traits...Ch. 4 - Prob. 16QPCh. 4 - Analysis of X-Linked Dominant and Recessive Traits...Ch. 4 - Analysis of Autosomal Recessive and Dominant...Ch. 4 - Analysis of X-Linked Dominant and Recessive Traits...Ch. 4 - Analysis of X-Linked Dominant and Recessive Traits...Ch. 4 - Analysis of X-Linked Dominant and Recessive Traits...Ch. 4 - Analysis of X-Linked Dominant and Recessive Traits...Ch. 4 - Prob. 23QPCh. 4 - Prob. 24QPCh. 4 - Variations in Phenotype Expression Define...Ch. 4 - Prob. 26QPCh. 4 - Variations in Phenotype Expression A genetic...Ch. 4 - Variations in Phenotype Expression Explain how...
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- Jan and Michael are both carriers for the cystic fibrosis allele. If Jan and Michael have five children, what the probability that three or more of the children will have the disease?arrow_forwardMrs. Dela Cruz suffers cystic fibrosis and married a carrier for the disease. What is the percentage that their offspring will express the disease?arrow_forwardMr. and Mrs. Smith are concerned because their own blood types are A and B, respectively, but their new son, Richard, is blood type O. Could Richard be the child of these parents?arrow_forward
- A man with type AB blood is married to a woman with type O blood. They have two natural childrenand one adopted child. Jane has type A blood, Bobby has type B blood, and Grace has type O blood.Which child was adopted?arrow_forwardJane has type O blood. Her child has type O blood. George's blood type is homozygous B. Could George be the father of Jane's baby?arrow_forwardBelow is a partial pedigree of hemophilia in the British Royal Family descended from Queen Victoria, who is believed to be the original "carrier" in this pedigree. Albert Victoria (1819-1901) Helena Empress Victoria Edward VII Alice of Hesse Beatrice Princess Leopold Duke of Albany Christian 66655 5858 Alice Kaiser George Wilhelm II V Princess Frederick (Alexandra) Irene Alix Tsarina Nikolas II of Athlone Victoria Leopold Maurice Eugenie (wife of Alfonso XIII) Analyze the pedigree and indicate which females are also certain to be carriers.arrow_forward
- If the parents have blood types that are both AB-, which children are likely?arrow_forwardStefan has launched a paternity suit to determine whether he is the father of an orphan residing in a monastery. Can mitochondrial DNA be used to trace the paternity? Explain.arrow_forwardI am focusing on the Russian Royal Families pedigree. The son Alexis has the hemaphilia trait. I need help trying to figure out if Alexis's hemaphillia trait is dominant/recessive and why?arrow_forward
- Explain why it was essential that Mendel perform his crosses using a large sample size?arrow_forwardHemophilia is an X-linked disease associated with the inability to produce specific proteins in the blood-clotting pathway. Shown above is a family pedigree tree in which family members afflicted with the disease are shown with filled-in squares (male) or circles (females). A couple is trying to determine the likelihood of passing on the disease to their future children (represented by the ? symbol above) because the hemophilia runs in the woman’s family 4.Assuming that the woman in the couple is a carrier, what is the probability that the couple’s first son will have hemophilia?arrow_forward3) Isabella has blood type O her son also has blood type O. She claims that her friend, Ivan, is the child's father. a) Ivan's blood type is A. Can he be excluded as the father on this evidence alone? b) Does the fact that Ivan's mother has type A blood and his father has type AB blood exclude him from being the parent? c) Does the additional information that Ivan's mother's parents are both AB permit him to be excluded?arrow_forward
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