Biology 2e
Biology 2e
2nd Edition
ISBN: 9781947172517
Author: Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher: OpenStax
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Chapter 4, Problem 42CTQ

Explain how the extracellular matrix functions.

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The diagram below illustrates a quorum sensing pathway from Staphylococcus aureus. Please answer the following questions. 1. Autoinduction is part of the quorum sensing system. Which promoter (P2 or P3) is critical for autoinduction? 2)This staphylococcus aureus grows on human wounds, causing severe infections. You would like to start a clinical trial to treat these wound infections. Please describe: a) What molecule do you recommend for the trial. Why? b) Your trial requires that Staphylococcus aureus be isolated from the wound and submitted to genome sequencing before admittance. Why? What are you testing for?  3) If a mutation arises where the Promoter P3 is constitutively active, how would that influence sensitivity to AIP? Please explain your rationale. 4) This pathway is sensitive to bacterial cell density. Describe two separate mutation that would render the pathway active independent of cell density. Briefly explain your rationale. Mutation 1 Mutation 2
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You have a bacterial strain with the CMU operon: a) As shown in the image below, the cmu operon encodes a peptide (Pep1), as well as a kinase and regulator corresponding to a two-component system. The cmu operon is activated when Pep 1 is added to the growth media. Pep1 is a peptide that when added extracellularly leads to activation of the Cmu operon. Pep1 cmu-kinase cmu-regulator You also have these genetic components in other strains: b) An alternative sigma factor, with a promoter activated by the cmu-regulator, that control a series of multiple operons that together encode a transformasome (cellular machinery for transformation). c) the gene cl (a repressor). d) the promoter X, which includes a cl binding site (and in the absence of cl is active). e) the gene gp (encoding a green fluorescence protein). Using the cmu operon as a starting point, and assuming you can perform cloning to rearrange any of these genomic features, how would you use one or more of these to modify the…

Chapter 4 Solutions

Biology 2e

Ch. 4 - In plant cells, the function of the lysosomes is...Ch. 4 - Which of the following is both in eukaryotic and...Ch. 4 - Tay-Sachs disease is a genetic disorder that...Ch. 4 - Which of the following is not a component of the...Ch. 4 - The process by which a cell engulfs a foreign...Ch. 4 - Which of the following is most likely to have the...Ch. 4 - Which of the following sequences correctly lists...Ch. 4 - Congenital disorders of glycosylation are a...Ch. 4 - Which of the following have the ability to...Ch. 4 - Which of the following do not play a role in...Ch. 4 - In humans, are used to move a cell within its...Ch. 4 - Which of the following are only in plant cells?...Ch. 4 - The key components of desmosomes are cadherins...Ch. 4 - Diseased animal cells may produce molecules that...Ch. 4 - In your everyday life, you have probably noticed...Ch. 4 - In what situation(s) would the use of a scanning...Ch. 4 - In what situation(s) would a transmission electron...Ch. 4 - What are the advantages and disadvantages of each...Ch. 4 - Explain how the formation of an adult human...Ch. 4 - Antibiotics are medicines that are used to fight...Ch. 4 - Explain why not all microbes are harmful.Ch. 4 - You already know that ribosomes are abundant in...Ch. 4 - What are the structural and functional...Ch. 4 - Why are plasma membranes arranged as a bilayer...Ch. 4 - In the context of cell biology, what do we mean by...Ch. 4 - In your opinion, is the nuclear membrane part of...Ch. 4 - What are the similarities and differences between...Ch. 4 - How do cilia and flagella differ?Ch. 4 - Describe how microfilaments and microtubules are...Ch. 4 - Compare and contrast the boundaries that plant,...Ch. 4 - How does the structure of a plasmodesma differ...Ch. 4 - Explain how the extracellular matrix functions.Ch. 4 - Pathogenic E. coil have recently been shown to...
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