FUNDAMENTALS OF BIOCHEM.-NEXTGEN ACCESS
5th Edition
ISBN: 9781119661450
Author: Voet
Publisher: WILEY
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Chapter 3, Problem 6E
Summary Introduction
Introduction: Reactions that are catalyzed by kinases are known as kinase-catalyzed reactions. In these reactions, one phosphoryl group from a nucleoside triphosphate is transferred by the kinase enzyme to the organic molecules. The kinase enzymes alter the structure of proteins by adding the phosphate groups to them by the process of phosphorylation. The principle source of the phosphoryl groups is adenosine triphosphate (ATP).
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At a pH equal to the isoelectric point (pl) of alanine, the net charge of alanine is zero. Two structures can be drawn that have a
net charge of zero, but the predominant form of alanine at its pl is zwitterionic.
CH3
H,N
CH3
**
H¸N-C
H
Zwitterionic
H
Uncharged
OH
Select statements that explain why alanine is predominantly zwitterionic at its pl.
pk of alanine's amino group is more than its pl.
pk of alanine's carboxyl group is more than its pl.
PK of alanine's carboxyl group is less than its pl.
pk of alanine's amino group is less than its pl.
Correct Answer
What fraction of alanine is in the completely uncharged form at its pl?
1 in 2.2 × 107
1 in 1.6 × 10²
1 in 4680
1 in 9460
How does a voltage-gated sodium channel work? Specifically, how and why does a change in voltage trigger their opening? Please be detailed
When sodium ions enter a neuron during depolarization, they trigger the opening of additional voltage-gated sodium channels nearby, creating a positive feedback loop where the influx of sodium ions further depolarizes the membrane, causing even more sodium channels to open and allowing more sodium ions to enter the cell, thus sustaining the depolarization process until the action potential peaks. But how and why exactly does the influx of sodium ions trigger more sodium channels to let in more sodium? Please explain
Chapter 3 Solutions
FUNDAMENTALS OF BIOCHEM.-NEXTGEN ACCESS
Ch. 3 - Prob. 1ECh. 3 - 2. Name the following nucleotide.
Ch. 3 - 3. In many organisms, DNA is modified by...Ch. 3 - 4. When cytosine is treated with bisulfite, the...Ch. 3 - 5. Kinases are enzymes that transfer a phosphoryl...Ch. 3 - 6. Kinases are enzymes that transfer a phosphoryl...Ch. 3 - 7. A diploid organism with a 45,000-kb haploid...Ch. 3 - 8. A segment of DNA containing 20 base pairs...Ch. 3 - 9. Explain why the strands of a DNA molecule can...Ch. 3 - 10. Explain why increasing the NaCl concentration...
Ch. 3 - 11. An enzyme from the human immunodeficiency...Ch. 3 - 12. How many different amino acids could...Ch. 3 - 13. The human genome contains thousands of...Ch. 3 - 14. By how many nucleotides, on average, do the...Ch. 3 - 15. The recognition sequence for the restriction...Ch. 3 - 16. Using the data in Table 3-2, identify...Ch. 3 - 17. The 13-Mb genome of the green alga...Ch. 3 - 18. Describe how to select recombinant clones if a...Ch. 3 - Prob. 19ECh. 3 - Prob. 20ECh. 3 - 21. Why is a genomic library larger than a cDNA...Ch. 3 - 22. Why do cDNA libraries derived from different...Ch. 3 - 23. Some RNA molecules me covalently modified by...Ch. 3 - 24. Would the modified nucleoside described in...Ch. 3 - 25. Draw the tautomeric form of adenine.
Ch. 3 - 26. Draw the tautomeric form of cytosine.
Ch. 3 - 27. The pK value for N1 of adenine is 3.64,...Ch. 3 - Prob. 28CQCh. 3 - Prob. 29CQCh. 3 - 30. Hypoxanthine can also base-pair with cytosine....Ch. 3 - 31. Describe the outcome of a chain-terminator...Ch. 3 - 32. Describe the outcome of a chain-terminator...Ch. 3 - 33. Calculate the number of clones required to...Ch. 3 - 34. You are attempting to clone a 250-kb segment...Ch. 3 - 35. Describe the possible outcome of a PCR...Ch. 3 - 36. Describe the possible outcome of a PCR...Ch. 3 - 37. Write the sequences of the two 12-residue...Ch. 3 - 38. A blood slain from a crime scene and blood...Ch. 3 - Prob. 1MTE
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