Biochemistry: Concepts and Connections
Biochemistry: Concepts and Connections
1st Edition
ISBN: 9780321839923
Author: Dean R. Appling, Spencer J. Anthony-Cahill, Christopher K. Mathews
Publisher: PEARSON
Question
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Chapter 3, Problem 16P
Interpretation Introduction

(a)

Interpretation:

The amount of free energy change involved in transporting 10-6 mole of glucose from the medium into the cellshould be calculated if the concentration of glucose inside a cell is 0.1 mM and the cell is suspended in a glucose solution of 0.01 mM.

Concept introduction:

The standard Gibbs free energy change is related to concentration of all the species involved in the reaction as follows:

ΔG = ΔG0 + RT ln Q

Here, ΔGo is standard Gibbs free energy change

ΔG is Gibbs free energy change

R is Universal gas constant

T is temperature

Q is reaction quotient

For movement of ions and species in and outside the cell, Gibbs free energy change can be calculated as follows:

ΔG = RT ln [ C ]in[ C ]out

Here, [ C ]in and [ C ]out is concentration of species inside and outside the cell respectively.

Interpretation Introduction

(b)

Interpretation:

The amount of free energy change involved in transporting 10-6 mole of glucose from the medium into the cell should be calculated if the intracellular and extracellular concentrations were 1 mM and 10 mM.

Concept introduction:

The standard Gibbs free energy change is related to concentration of all the species involved in the reaction as follows:

ΔG = ΔG0 + RT ln Q

Here, ΔGo is standard Gibbs free energy change

ΔG is Gibbs free energy change

R is Universal gas constant

T is temperature

Q is reaction quotient

For movement of ions and species in and outside the cell, Gibbs free energy change can be calculated as follows:

ΔG = RT ln [ C ]in[ C ]out

Here, [ C ]in and [ C ]out is concentration of species inside and outside the cell respectively.

Interpretation Introduction

(c)

Interpretation:

The number moles of ATP should be calculated.

Concept introduction:

The standard Gibbs free energy change is related to concentration of all the species involved in the reaction as follows:

ΔG = ΔG0 + RT ln Q

Here, ΔGo is standard Gibbs free energy change

ΔG is Gibbs free energy change

R is Universal gas constant

T is temperature

Q is reaction quotient

For movement of ions and species in and outside the cell, Gibbs free energy change can be calculated as follows:

ΔG = RT ln [ C ]in[ C ]out

Here, [ C ]in and [ C ]out is concentration of species inside and outside the cell respectively.

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