Chapter 29, Problem 29.45AP

(a)

Interpretation Introduction

Interpretation:

The result of the allosteric interaction with haemoglobin as oxygen binds to it has to be given.

Concept Introduction:

Haemoglobin:

• Composed of four polypeptide chain with a quaternary structure.
• A central heme molecule is there in each protein chain and each of the four hemes can bind with one ${\text{O}}_{\text{2}}$ molecule.
• Each heme molecule in its centre has iron(II) (${\text{Fe}}^{\text{+2}}$).
• The bright red haemoglobin with four oxygens is called oxy haemoglobin.
• The dark red-purple haemoglobin in which one or more oxygen is lost is called deoxyhaemoglobin.

Allosteric interaction: The protein haemoglobin is an allosteric protein. The meaning of allosteric interaction is that binding of oxygen to one of the subunits is affected by its interactions with the other subunits.

(b)

Interpretation Introduction

Interpretation:

The result of the allosteric interaction with haemoglobin as oxygen releases from it has to be given.

Concept Introduction:

Haemoglobin:

• Composed of four polypeptide chain with a quaternary structure.
• A central heme molecule is there in each protein chain and each of the four hemes can bind with one ${\text{O}}_{\text{2}}$ molecule.
• Each heme molecule in its centre has ${\text{Fe}}^{\text{+2}}$
• The bright red haemoglobin with four oxygens is called oxy haemoglobin.
• The dark red-purple haemoglobin in which one or more oxygen is lost is called deoxyhaemoglobin.

Allosteric interaction: The protein haemoglobin is an allosteric protein. The meaning of allosteric interaction is that binding of oxygen to one of the subunits is affected by its interactions with the other subunits.