What is Life? A Guide to Biology with Physiology
3rd Edition
ISBN: 9781464157745
Author: Jay Phelan
Publisher: W. H. Freeman
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Chapter 26, Problem 10MC
Summary Introduction
Introduction:
Autoimmunity occurs when the body's immune system attacks its own cells.
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Define the following terms:a. T cellsb. B cellsc. cellular immunityd. humoral immunitye. myoadenylate deaminase deficiency
Which of the following is not a function of antibodies?
Select one:
a. They neutralize pathogens by masking the pathogen surface.
b. They act as molecular adaptors that bridge together pathogen and phagocyte surfaces.
c. They exert toxic effects directly.
d. They act as opsonins that mediate phagocytosis.
e. They activate complement fixation.
Discuss the effect of the following physiological changes on the effectiveness of the body’s immune response: a. Taking antacids on a regular basis. b. Changes caused by smoking in the cilia in the respiratory epithelium c. Cut or abrasion in the skin. Explain how the body tries to prevent pathogenic entry into the body
2.3. Evaluate factors that affect the efficiency of the body’s first line of defence
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Chapter 26 Solutions
What is Life? A Guide to Biology with Physiology
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- Any aspect of the immune system can be deficient. Which of the following deficiencies would primarily affect the BARRIER function of immunity? Group of answer choices A. Complement Deficiencies, in which a variety of complement proteins do not function properly B. DiGeorge Syndrome, in which the thymus does not develop properly C. Selective IgA deficiency, in which IgA antibodies are produced in very low amounts D. Severe Combined Immune Deficiency (SCID), in which all T and B cell functions are absentarrow_forwardWhich of the following statements is TRUE? A. Lymphatic vessels and veins have valves B. All Lymphocytes are part of our Non-specific immune defenses C. Chicken pox vaccines involve the injection of antibodies D. Spleens are lymph nodes which drain lymph fluid back to the blood circulation What do complement proteins, inflammation and fever have in common? A. All are part of the specific defenses mechanisms of the immune system (also called adaptive immunity) B. All are processes that occur in lymph nodes C. All occur as part of the non-specific defenses D. All occur as a direct result of antigen processing in an antigen processing cellarrow_forwardAn essential property of the immune system is self-regulation. An immune response that is not adequate can lead to immunodeficiency, whereas an immune response that is excessive can lead to conditions from allergic responses to autoimmune diseases. Which of these is not an example of a breakdown of the self-regulation of the immune system?a. Multiple sclerosisb. Huntington diseasec. Systemic lupusd. Fibromylagiaarrow_forward
- Compare and contrast innate and adaptive immunity by matching the following characteristics with the correct arm of immunity, using I for innate and A for adaptive: a. Is the first to engage on initial encounter with antigen b. Is the most pathogen specific c. Employs T and B lymphocytes d. Adapts during the response e. Responds identically during a first and second exposure to the same antigen f. Responds more effectively during a subsequent exposure g. Includers a memory component h. Is the target of vaccination i. Can involve the use of PAMP receptors j. Involves antigen-specific receptors binding to pathogens k. Can be mediated by antibodiesarrow_forwardThe four characteristics of adaptive immunity include all of the following except a. activation by a specific antigen. b. memory. c. production of clones of cells that have the same TCR or BCR. d. effective against a wide array of pathogens.arrow_forwardThe immune system includes the various responses the body uses to ensure survival in the presence of disease-causing agents. Identify the example of innate immunity. A. Infected host cells are killed by toxic proteins from cytotoxic T cells. B. Toll-like receptors bind to foreign molecule fragments to initiate immune response. C. CD4 accessory proteins on the helper T cell surface bind to class II MHC molecules. D. IgE antibodies recognize and attach to pollen grains, stimulating an allergic reaction.arrow_forward
- Which of the following statements are true for antigen presentation. a. Antigen presentation means that other cells attach the pathogen first and present it to T cells. b. Antigen-presenting cells display protein fragments, resulting from the digestion of the pathogen, in complex with MHC receptor to B cells c. Antigen presenting cells display protein fragments, resulting from the digestion of the pathogen, in complex with MHC receptor on their surface. d. Antigen-presenting cells are phagocytic cells e. Antigen presentation is required for T cell activation f. Cytokines released by macrophages are required for T cell activation g. T cell receptors recognize the MHC receptors in complex with antigen fragments displayed by antigen-presenting cells. h. Phagocytic cells are involved in innate immunity. Therefore they have no role in T-cell activationarrow_forwardExplain why each choice (a-d) is correct or incorrect. Which of the following examples below describes an autoimmune disease? a. Infection and death of T helper cells by a virus, resulting in a loss of adaptive immunity b. Release of bacterial endotoxins that block acetylcholine release result in muscle paralysis. c. Antibody binding to acetylcholine receptors of the motor end plate resulting in muscle weakness. d. Uncontrolled cell division resulting in cell surface abnormalities recognized by NK cells.arrow_forwardAntibodies against a specific antigen can be injected into a person to provide passive immunity. For which reason is this NOT as effective as the process of vaccination with that antigen? Select one: a. Injection of antibodies may cause allergic reactions, while vaccination never causes allergic reactions. b. Injection of antibodies does not provide long-lasting immunity, and vaccination with antigens triggers a clonal selection of B cells and cytotoxic T cells. c. Vaccination with antigens triggers a clonal selection of B cells and cytotoxic T cells. d. Injection of antibodies does not provide long-lasting immunity. e. Injection of antibodies does not provide long-lasting immunity and may cause allergic reactions, while vaccination never causes allergic reactions.arrow_forward
- For each of the following statements, indicate whether the statement is true or false. If false, explain why. a. Booster shots are required because repeated exposure to an antigen builds a stronger immune response b. The gene for the T-cell receptor must be cut and spliced together before it can be expressed c Our bodies face the greatest onslaught from foreign invaders through our skin d. Increased production of antibody in the immune system is driven by the presence of antigen e. Innate immunity is deployed only during the primary response, and adaptive immunity begins during a secondary response f. Autoimmunity and immunodeficiency are two different terms for the same set of general disorders g. If you receive intravenous immunoglobulin to treate a snakebite, you will be protected from the vemom of this type of snake in the future, but not from the venom of other types of snakes h. Innate and adaptive immunity work collaboratively to mount an immune response against pathogens i. The…arrow_forwardExplain why each choice (a-d) is correct or incorrect. B lymphocytes are categorized as part of the adaptive branch of the immune system for all of the following reasons but one. Which of the following is NOT one of the reasons B lymphocytes are considered part of the adaptive immunity? a.They produce memory cells when activated. b.Their receptors will bind to only one antigen. c.They require co-stimulation from an activated T helper cell d. They are a first line of defense that can begin killing pathogens immediatelyarrow_forwardAn example of innate immune cells are: A. Macrophages B. Dendritic cells C. T cells D. B cells E. A and B onlyarrow_forward
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