What is Life? A Guide to Biology with Physiology
3rd Edition
ISBN: 9781464157745
Author: Jay Phelan
Publisher: W. H. Freeman
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Chapter 26, Problem 8MC
Summary Introduction
Introduction:
Helper T cells play a central role in helping in the functions of other immune cells.
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Students have asked these similar questions
CHAPTER 20
The Lymphatic System and Immunity
Matching
SECTION 3 Revie w
Match each lettered term with the most closely related description.
a. opsonization
1
b. helper T cells
Two parallel pairs of polypeptide chains
Found on helper T cells
C. antibody
d. class II MHC
3
Active and passive
4 Transfer of antibodies
e. costimulation
Attacked by HIV
f. IgM
6 Enhances phagocytosis
g. class I MHC
h. IgG
7 MHC proteins present in the plasma
membranes of all nucleated cells
i. passive immunity
j. anaphylaxis
8
Differentiate into memory and plasma cells
9
MHC proteins present in the plasma
membranes of all APCS and lymphocytes
9
k. CD4 markers
10
I. acquired immunity
10 Antibodies used to determine blood type
11
m. B lymphocytes
11 Secondary binding process required for T cell activation
12
12 Accounts for 80 percent of all immunoglobulins
13
13 Circulating allergen stimulates mast cells throughout body
Match each lettered term with the
Which of the following pairs is mismatched?
a. T-cell activation: cell division and differentiation
b. effector B cell: plasma cell
c. plasma cell: antibody secretion
d. helper T cell: kills pathogen-infected cells
e. helper T cell: facilitates the differentiation of B cells.
Which of the following statements regarding T cells activated by specific antigen is incorrect?
a. They receive co-stimulatory signals through CD28.
b. They suppress expression of sphingosine 1-phosphate (SIP).
c. They take several days before differentiating into effector T cells.
d. They cease to secrete and respond to interleukin-2 (IL-2).
e. They begin to express CTLA4, which serves to limit T-cell proliferation.
Chapter 26 Solutions
What is Life? A Guide to Biology with Physiology
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Similar questions
- Which of the following best describes the movement of a T cell through a lymph node? a. It enters via efferent lymphatics and exits via the bloodstream. b. It enters via afferent lymphatics and exits via the bloodstream. c. It enters via the bloodstream and exits via afferent lymphatics. d. It enters via the bloodstream and exits via the bloodstream. e. It enters via the bloodstream and exits via efferent lymphatics.arrow_forwardTo become a fully activated, antibody-secreting cell, B cells usually need: a. to encounter an antigen or receive a signal delivered by a helper T cell. b. to ingest a foreign invader such as a microobe. c. activation by a plasma cell d. contact with an antigen and helper T cell cytokinesarrow_forwardExplain why each choice (a-d) is correct or incorrect. Which statement is true about T cells? a. They usually directly recognize antigens, which then activates a subpopulation of killer cells b. Their proliferation is enhanced by interleukins 1 and 2. c. Once activated, they cannot secrete cytokines. d. They will develop into cytotoxic T cells if antigen is complexed with class II MHC proteins.arrow_forward
- The immune system includes the various responses the body uses to ensure survival in the presence of disease-causing agents. Identify the example of innate immunity. A. Infected host cells are killed by toxic proteins from cytotoxic T cells. B. Toll-like receptors bind to foreign molecule fragments to initiate immune response. C. CD4 accessory proteins on the helper T cell surface bind to class II MHC molecules. D. IgE antibodies recognize and attach to pollen grains, stimulating an allergic reaction.arrow_forwardWhich of the following is not a function of antibodies? Select one: a. They neutralize pathogens by masking the pathogen surface. b. They act as molecular adaptors that bridge together pathogen and phagocyte surfaces. c. They exert toxic effects directly. d. They act as opsonins that mediate phagocytosis. e. They activate complement fixation.arrow_forwardIdentify each immune response as either humoral (H) or cellular (C). A. release of histamine causes itching & sneezing B. cytotoxic T lymphocytes kill infected cells C. plasma B cells are cloned D. antibodies mark pathogen’s antigens E. cytokines signal B & T cell production F. macrophage presents antigen to the matching receptor on helper T cellarrow_forward
- Which of the following explains why dendritic cells, but not macrophages or B cells, contribute to the activation of naive T cells? a. Macrophages and B cells do not express MHC class II molecules until they are activated. b. Dendritic cells upregulate B7 after engaging innate immunity receptors at sites of infection. c. Dendritic cells express higher levels of CTLA4. d. Macrophages and B cells do not process antigen. e. Dendritic cells use Toll-like receptors to hold antigen in place for extended periods of time.arrow_forwardWhich of the following pairs is mismatched? a. plasma cell: mediation of phagocytosis and killing of microorganisms in the plasma b. megakaryocyte: formation of platelets c. dendritic cell: activation of adaptive immune responses d. natural killer cell: develops from a common lymphoid progenitor e. neutrophil: formation of pus f. regulatory T cell: inhibition of T-cell activity.arrow_forwardWhich of the following statements regarding intraepithelial lymphocytes is false? (Select all that apply.) a. They comprise approximately 10% of the cells in the mucosal epithelium. b. They are composed of both CD4 and CD8 T cells. c. They are separated from the lamina propria by a basement membrane. d. They are activated effector T cells with a narrow range of antigen specificities. e. They do not include NK cells. f. They express the α4:β7 integrin that binds to E-cadherin on epithelial surfaces.arrow_forward
- Which of the following statements are true for antigen presentation. a. Antigen presentation means that other cells attach the pathogen first and present it to T cells. b. Antigen-presenting cells display protein fragments, resulting from the digestion of the pathogen, in complex with MHC receptor to B cells c. Antigen presenting cells display protein fragments, resulting from the digestion of the pathogen, in complex with MHC receptor on their surface. d. Antigen-presenting cells are phagocytic cells e. Antigen presentation is required for T cell activation f. Cytokines released by macrophages are required for T cell activation g. T cell receptors recognize the MHC receptors in complex with antigen fragments displayed by antigen-presenting cells. h. Phagocytic cells are involved in innate immunity. Therefore they have no role in T-cell activationarrow_forwardWhich of the following can serve as antigen-presenting cells (APCs)?a. T cells b. B cells c. macrophages d. dendritic cells e. b, c, and darrow_forwardA number of minor cancerous cells and infected viruses, such as Epstein Barr (EBV), are able to go undetected by cytotoxic T cell degradation by what possible mechanism? a. the production of normal class I MHC molecule b. helper T cell activation c. the deactivation of the complement system d. tumor antigen expression e. the production of the class II major histocompatability (MHC) moledulearrow_forward
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