Concept explainers
(a)
Interpretation:
In citric acid cycle the eight enzyme with name that indicates the reverse reaction should be given.
Concept Introduction:
Citric Acid Cycle: It involves 8 series reaction which converts acetyl group present in acetyl coenzyme A into 2
(b)
Interpretation:
In glycolysis the enzyme with name that indicates the reverse reaction should be given.
Concept introduction:
Glycolysis: It is pathway which describes conversion of one molecule of glucose into 2
pyruvate molecules. It involves totally 10 set of reactions with it.
Protein catabolism: It is defined as breakdown of proteins into smaller units that is into amino acids gets transported finally
Citric Acid Cycle: It involves 8 series reaction which converts acetyl group present in acetyl coenzyme A into 2
Substrate: The molecule where the reaction takes place with help of enzymes.
Enzyme: The proteins that helps
Oxidation: The oxidation is reaction that involves addition of oxygen atom or loss of electrons or removal of hydrogen atom present in the chemical compound.
Reduction: It involves removal of oxygen or addition of hydrogen to the chemical compound.
Coenzyme: They are non-proteins molecules which helps enzymes for catalyzing the reaction.
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Organic Chemistry (8th Edition)
- The first step of the metabolic process known as glycolysis is the conversion of glucose to glucose- 6-phosphate. This process has a positive value for rG' Glucose + Pi Glucose-6-phosphate + H2O rG' = +13.8 kJ/mol-rxn This reaction is coupled to the hydrolysis of ATP ATP + H2O ADP + Pi rG' = -30.5 kJ/mol-rxn What is the sum of these two equations and the value of rG' for the coupled reaction? Is the coupled reaction product-favored at equilibrium?arrow_forwardPut the following substances in the correct order in which they are first encountered in the common metabolic pathway: succinate, FeSP, CO2, FADH2.arrow_forwardNADH and FADH2 can "create" ATP only if the cell can do electron transport True Falsearrow_forward
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- 2. These are known as metabolic reactions in which large biochemical molecules are broken down to smaller ones A. Anabolic reaction B. Catabolic reaction C. Metabolic reaction D. All of the above E. None of the abovearrow_forward1. The following reactions can be coupled in the citrate cycle. Succinyl-CoA GDP + Pi. succinate + CoA GTP AGO'= -34.0 kJ/mol AGO'= 30.5 kJ/mol a) Write the net reaction. Calculate AGº for the coupled reaction. Is the reaction favorable? b) Write the equilibrium constant in terms of reactant and product concentration. Calculate the equilibrium constant, K, for the coupled reaction at 37°C. c) If the ratio of [GTP/[GDP] in the cell is 22, the [CoA]/[succinyl-CoA] ratio is 0.20, and the [Pi] is 1.3mM, determine the [Succinate] at equilibrium. (Pay attention to concentration units) d) If the [GTP/[GDP] falls to 4.0, calculate AG', keeping all other concentrations the same. If the [GTP/[GDP] increases to 75, calculate AG', keeping all other concentrations the same. e) What conclusion can you reach about the direction of the reaction under these cellular conditions? Is this reaction reversible or irreversible?arrow_forwardChemistry What is the main aspect that the enzymes succinyl-CoA synthetase, pyruvate kinase, and phosphoglycerate kinase have in common?arrow_forward
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