
Concept explainers
Interpretation: The starting carbonyl materials that are needed to prepare X by using a directed aldol reaction are to be identified. The reagents that are needed to convert X to donepezil are to be identified.
Concept Introduction: The directed aldol reaction is a type of cross aldol reaction. This directed aldol reaction categorizes the carbonyl compounds into the nucleophilic enolate and other the carbonyl compound which can react at the electrophilic carbonyl carbon atom.
Aldol reaction is the condensation reaction of the

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Chapter 24 Solutions
Organic Chemistry
- If possible, please provide the formula of the compound 3,3-dimethylbut-2-enal.arrow_forwardSynthesize 1,4-dibromobenzene from acetanilide (N-phenylacetamide) using the necessary organic or inorganic reagents. Draw the structures of the compounds.arrow_forwardIndicate the products obtained by mixing (3-oxo-3-phenylpropyl)triphenylphosphonium bromide with sodium hydride.arrow_forward
- We mix N-ethyl-2-hexanamine with excess methyl iodide and followed by heating with aqueous Ag2O. Indicate the major products obtained.arrow_forwardIndicate the products obtained by mixing acetophenone with iodine and NaOH.arrow_forwardIndicate the products obtained by mixing 2-Propanone and ethyllithium and performing a subsequent acid hydrolysis.arrow_forward
- Indicate the products obtained if (E)-2-butenal and 3-oxo-butanenitrile are mixed with sodium ethoxide in ethanol.arrow_forwardQuestion 3 (4 points), Draw a full arrow-pushing mechanism for the following reaction Please draw all structures clearly. Note that this intramolecular cyclization is analogous to the mechanism for halohydrin formation. COH Br + HBr Brarrow_forwardIndicate the products obtained if 2,2-dimethylpropanal and acetaldehyde are mixed with sodium ethoxide in ethanol.arrow_forward
- Indicate the products obtained if 2,2-dimethylpropanal and acetaldehyde are reacted with sodium ethoxide in ethanol.arrow_forward2,2-Dimethylpropanal and acetaldehyde are reacted with sodium ethoxide in ethanol. Indicate the products obtained.arrow_forwardAdd conditions above and below the arrow that turn the reactant below into the product below in a single transformationADS fint anditions 百 Abl res condinese NC ง Add on condtions 1.0 B H,N.arrow_forward
- Organic Chemistry: A Guided InquiryChemistryISBN:9780618974122Author:Andrei StraumanisPublisher:Cengage Learning
