Biology: The Unity and Diversity of Life (MindTap Course List)
Biology: The Unity and Diversity of Life (MindTap Course List)
15th Edition
ISBN: 9781337408332
Author: Cecie Starr, Ralph Taggart, Christine Evers, Lisa Starr
Publisher: Cengage Learning
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Chapter 23, Problem 3CT
Summary Introduction

To explain: Why it is harder to fight fungi than bacteria.

Concept introduction: Fungi are the heterotrophic eukaryotic organisms with size ranging from microscopic yeasts to macroscopic mushrooms. Many of the members coming under the kingdom fungi have both beneficial and fatal role on human beings. Fungi like yeast and penicillin have a very crucial and beneficial role in economy. Though there are several economic uses of fungal members that exist, many are very dangerous to human beings. Fungal infections on the dermal layer of the skin are called as mycoses, and it is not so dangerous naturally, but in immune-suppressed people, it may lead to severe problems.

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Health professionals refer to fungal skin diseases as "“tineas" and name them according to the region affected. Fungal skin diseases are persistent, in part, because fungi can penetrate deeper layers of skin than can ointments and creams. There are fewer antifungal drugs than ones, and antifungals often have more severe side effects. Reflect on the evolutionary relationships among bacteria, fungi, and humans. 1. List 5 different "Tineas" to show the connection between the name and the body parts affected from them. 2. Are fungi unicellular or multicellular organism? 3. Why it is harder to fight fungi than bacteria? 4. Why antifungals have more severe side effects?
Many fungal infections of humans are considered to be opportunistic, meaning that fungi that are normally free-living (usually in soil) can sometimes survive, and even thrive, on or inside the human body. From the fungal “point of view,” what unique challenges would be encountered when trying to survive on human skin? What about inside human lungs?
Why do yeasts generally have to be cultured for longer periods than most bacteria? Can bacteriological media be used for the cultivation of molds? Explain your answer. What is the difference between vegetative and aerial mycelia? What are the three classes of antifungal drugs based on their mechanism/site of action? Describe the mode of action of each class. Name one fungal virulence factors that promote fungal colonization. Explain the mechanism. Name one fungal virulence factors that damage the host. Explain the mechanism.
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