(a)
Interpretation: The intermediates
Concept introduction: Ibuprofen is a synthetic compound which is widely used as a drug and as an analgesic and anti-inflammatory. It is synthesized from
(b)
Interpretation: The product formed by the direct alkylation of compound
Concept introduction: Ibuprofen is a synthetic compound which is widely used as a drug and as an analgesic and anti-inflammatory. It is synthesized from
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Organic Chemistry
- are involved in the regulation of glucose metabolism and in control tissue swelling by the control of inflammation, while regulating cellular salt balance between Na+ and K+. a.glucocorticoids, mineralocorticoids b. mineralocorticoids, glucocorticoids c. androgen, estrogen d. estrogen, androgen Which of the following represents an aldonic acid? OH OH но, но OH но —н но Но HO HO H но но H H- -OH -OH H OH H FOH H- -OH- OH HO но HO. OH II III IV V Refer to the structures. Which of the following compounds will react with acetyl chloride to give an amide and ester, respectively? NH2 ÇOOH CH3 он CHO II II IV V The six groups of enzymes are the following: I. Oxidoreductases II. Transferases III. Hydrolases IV. Isomerases V. Lyases VI. Ligases Fill in the blanks: catalyze hydrolysis while catalyze bond formation.arrow_forwardPart A: Draw the product of the reaction of propylamine with water Part B: Draw the product of the neutralization of propylamine with HBr Part C: Draw the product of the reaction of N-methylaniline with waterarrow_forwardTreatment of α,β-unsaturated carbonyl compound X with base forms the diastereomer Y. Write a stepwise mechanism for this reaction. Explain why one stereogenic center changes configuration but the other does not.arrow_forward
- X Upon ozonolysis, Compound X produces two compounds: Compound Y and Compound Z. Compound Y can also be prepared from the following synthetic route: PCC 1. R₂BH, THF 1. Mg. Et₂O PCC Compound Y 2. CH₂Cl₂ 2. NaOH, HO CH₂Cl₂ 3. H₂O* From this information, draw the structures of Compounds X, Y, and Z. For Compounds X and Z, different substituents are possible. For grading purposes, just use hydrogens as the substituents. Br مرد →] ►arrow_forward1. CN Br 2. LiAlH4 3. H₂O NH2 2a Primary amines can be prepared from nitriles by reduction with LiAlH4. The two-step sequence involves SN2 displacement of halide ion by cyanide ion followed by reduction, and yields a primary amine with one more carbon than was present in the alkyl halide. Draw curved arrows to show the movement of electrons in this step of the mechanism. Arrow-pushing Instructions Br CEN: -C=N: Brarrow_forwardKetones and aldehydes react with sodium acetylide (the sodium salt of acetylene) to give alcohols, as shown in the following example: R, OH 1. HC=C: Na* 2. Hзо C. R2 R2 HC Draw the structure of the major reaction product when the following compound reacts with sodium acetylide, assuming that the reaction takes preferentially from the Re face of the carbonyl group. Use the wedge/hash bond tools to indicate stereochemistry where it exists. You do not have to explicitly draw H atoms. If a group is achiral, do not use wedged or hashed bonds on it.arrow_forward
- b. Which of the following is the structure of acetic anhydride? si OH c. When 4-ethoxyaniline reacts with acetic anhydride, what new functional group or type of compound is formed? O acid anhydride acetal amide O esterarrow_forwarda-phellandrene and ß-phellandrene are two isomeric diene-containing terpene compounds isolated from eucalyptus plants that are used in fragrances due to their minty and citrusy odors. Use these two compounds to answer the following two questions: a. The addition of 1 equivalent of bromine at room temperature to the phellandrenes will give three possible di-brominated products. Select either a- or ß-phellandrene for this question and draw it in the left box - you can answer this question with either isomer. Draw all three products in the colored boxes depicted - you do not need to depict newly formed stereocenters or show mechanisms. OR a-phellandrene B-phellandrene product 1 select either a- or B-phellandrene product 2 Br₂ room temperature 3 possible products (see below) product 3arrow_forwardWrite the complete mechanism for the hydroxide ion catalyze reaction of cyclohexanone and 1-methylcyclohexanecarbaldehydearrow_forward
- The reaction of N−bromosuccinimide with 4−methyl−3−nitroanisole has been reported in the chemical literature. This reaction yields a single product in 95% yield. Identify the product formed from this starting material.arrow_forward10. The Wolff-Kishner reaction, in which an aldehyde or ketone is treated with NH2NH2 and KOH, is: a) an oxidation c) an SN2 reaction b) a reduction d) a hydration 11. Which of these is most likely to dissolve in 5% NaOH? a) 1-decanol b) decanal c) decanoic acid d) 2-decanone 12. The following compound forms a cyclic hemiacetal all by itself. Draw the structure of that hemiacetal.arrow_forwardEsterification reactions, such as the one below, is a poor synthetic strategy as it leads to poor yields of the ester. What alternative could be done to produce more p-methylphenyl acetate? H20 HO Replace the p-methylphenol with p-chlorotoluene. Replace acetic acid with acetate. O Replace acetic acid with acetyl chloride. O Replace the aromatic alcohol with a phenolate.arrow_forward
- Organic ChemistryChemistryISBN:9781305580350Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. FootePublisher:Cengage LearningOrganic Chemistry: A Guided InquiryChemistryISBN:9780618974122Author:Andrei StraumanisPublisher:Cengage Learning