Devise a synthesis of valproic acid [ ( CH 3 CH 2 CH 2 ) 2 CHCO 2 H ] , a medicine used to treat epileptic seizures, using the malonic ester synthesis.
Devise a synthesis of valproic acid [ ( CH 3 CH 2 CH 2 ) 2 CHCO 2 H ] , a medicine used to treat epileptic seizures, using the malonic ester synthesis.
Solution Summary: The author explains how the malonic ester synthesis is used to convert diethyl malonate into a carboxylic acid.
Devise a synthesis of valproic acid
[
(
CH
3
CH
2
CH
2
)
2
CHCO
2
H
]
, a medicine used to treat epileptic seizures, using the malonic ester synthesis.
(f) SO:
Best Lewis Structure
3
e group geometry:_
shape/molecular geometry:,
(g) CF2CF2
Best Lewis Structure
polarity:
e group arrangement:_
shape/molecular geometry:
(h) (NH4)2SO4
Best Lewis Structure
polarity:
e group arrangement:
shape/molecular geometry:
polarity:
Sketch (with angles):
Sketch (with angles):
Sketch (with angles):
1.
Problem Set 3b
Chem 141
For each of the following compounds draw the BEST Lewis Structure then sketch the molecule (showing
bond angles). Identify (i) electron group geometry (ii) shape around EACH central atom (iii) whether the
molecule is polar or non-polar (iv)
(a) SeF4
Best Lewis Structure
e group arrangement:_
shape/molecular geometry:
polarity:
(b) AsOBr3
Best Lewis Structure
e group arrangement:_
shape/molecular geometry:
polarity:
Sketch (with angles):
Sketch (with angles):
(c) SOCI
Best Lewis Structure
2
e group arrangement:
shape/molecular geometry:_
(d) PCls
Best Lewis Structure
polarity:
e group geometry:_
shape/molecular geometry:_
(e) Ba(BrO2):
Best Lewis Structure
polarity:
e group arrangement:
shape/molecular geometry:
polarity:
Sketch (with angles):
Sketch (with angles):
Sketch (with angles):
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