The given conversion is to be accomplished with the help of enamine synthesis using pyrrolidine as the secondary amine . Concept introduction: When aldehydes or ketones react with a secondary amine, formation of enamine takes place. The nitrogen analog of an enol is known as enamine. From the resonating structures of enamine, it is clear that it nucleophilic in nature. Reactivity of enamines is higher than an enol but less than an enolate ion. Milder conditions are favored for enamine reactions.

Question

Want to see the full answer?

Answer 1

Question

Definition Definition Organic compounds that have a carbonyl group, C=O, as their functional group. The carbonyl group in aldehydes is placed at the end of the molecular structure, which means the C=O is attached to one hydrogen atom and an alkyl group or a benzene ring. Just like all the other homologous series in organic chemistry, the naming of aldehydes uses the suffix “-al”. The general molecular formula is C n H 2n O.

Chapter 22.4, Problem 22.9P

(a)

Interpretation Introduction

Interpretation:

The given conversion is to be accomplished with the help of enamine synthesis using pyrrolidine as the secondary amine.

Concept introduction:

When aldehydes or ketones react with a secondary amine, formation of enamine takes place. The nitrogen analog of an enol is known as enamine. From the resonating structures of enamine, it is clear that it nucleophilic in nature. Reactivity of enamines is higher than an enol but less than an enolate ion. Milder conditions are favored for enamine reactions.

(b)

Interpretation Introduction

Interpretation:

The given conversion is to be accomplished with the help of enamine synthesis using pyrrolidine as the secondary amine.

Concept introduction:

When aldehydes or ketones react with a secondary amine, formation of enamine takes place. The nitrogen analog of an enol is known as enamine. From the resonating structures of enamine, it is clear that it nucleophilic in nature. Reactivity of enamines is higher than an enol but less than an enolate ion. Milder conditions are favourable for enamine reactions.

(c)

Interpretation Introduction

Interpretation:

The given conversion is to be accomplished with the help of enamine synthesis using pyrrolidine as the secondary amine.

Concept introduction:

When aldehydes or ketones react with a secondary amine, formation of enamine takes place. The nitrogen analog of an enol is known as enamine. From the resonating structures of enamine, it is clear that it nucleophilic in nature. Reactivity of enamines is higher than an enol but less than an enolate ion. Milder conditions are favored for enamine reactions.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

You are trying to decide if there is a single reagent you can add that will make the following synthesis possible without any other major side products: xi 1. ☑ 2. H₂O хе i Draw the missing reagent X you think will make this synthesis work in the drawing area below. If there is no reagent that will make your desired product in good yield or without complications, just check the box under the drawing area and leave it blank. Click and drag to start drawing a structure. There is no reagent that will make this synthesis work without complications. : ☐ S ☐

Predict the major products of this organic reaction: H OH 1. LiAlH4 2. H₂O ? Note: be sure you use dash and wedge bonds when necessary, for example to distinguish between major products with different stereochemistry. Click and drag to start drawing a structure. G C टे

For each reaction below, decide if the first stable organic product that forms in solution will create a new C-C bond, and check the appropriate box. Next, for each reaction to which you answered "Yes" to in the table, draw this product in the drawing area below. Note for advanced students: for this problem, don't worry if you think this product will continue to react under the current conditions - just focus on the first stable product you expect to form in solution. NH2 CI MgCl ? Will the first product that forms in this reaction create a new CC bond? Yes No MgBr ? Will the first product that forms in this reaction create a new CC bond? Yes No G टे

Answer 2

Question

Definition Definition Organic compounds that have a carbonyl group, C=O, as their functional group. The carbonyl group in aldehydes is placed at the end of the molecular structure, which means the C=O is attached to one hydrogen atom and an alkyl group or a benzene ring. Just like all the other homologous series in organic chemistry, the naming of aldehydes uses the suffix “-al”. The general molecular formula is C n H 2n O.

Chapter 22.4, Problem 22.9P

(a)

Interpretation Introduction

Interpretation:

The given conversion is to be accomplished with the help of enamine synthesis using pyrrolidine as the secondary amine.

Concept introduction:

When aldehydes or ketones react with a secondary amine, formation of enamine takes place. The nitrogen analog of an enol is known as enamine. From the resonating structures of enamine, it is clear that it nucleophilic in nature. Reactivity of enamines is higher than an enol but less than an enolate ion. Milder conditions are favored for enamine reactions.

(b)

Interpretation Introduction

Interpretation:

The given conversion is to be accomplished with the help of enamine synthesis using pyrrolidine as the secondary amine.

Concept introduction:

When aldehydes or ketones react with a secondary amine, formation of enamine takes place. The nitrogen analog of an enol is known as enamine. From the resonating structures of enamine, it is clear that it nucleophilic in nature. Reactivity of enamines is higher than an enol but less than an enolate ion. Milder conditions are favourable for enamine reactions.

(c)

Interpretation Introduction

Interpretation:

The given conversion is to be accomplished with the help of enamine synthesis using pyrrolidine as the secondary amine.

Concept introduction:

When aldehydes or ketones react with a secondary amine, formation of enamine takes place. The nitrogen analog of an enol is known as enamine. From the resonating structures of enamine, it is clear that it nucleophilic in nature. Reactivity of enamines is higher than an enol but less than an enolate ion. Milder conditions are favored for enamine reactions.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 3

Question

Definition Definition Organic compounds that have a carbonyl group, C=O, as their functional group. The carbonyl group in aldehydes is placed at the end of the molecular structure, which means the C=O is attached to one hydrogen atom and an alkyl group or a benzene ring. Just like all the other homologous series in organic chemistry, the naming of aldehydes uses the suffix “-al”. The general molecular formula is C n H 2n O.

Chapter 22.4, Problem 22.9P

(a)

Interpretation Introduction

Interpretation:

The given conversion is to be accomplished with the help of enamine synthesis using pyrrolidine as the secondary amine.

Concept introduction:

When aldehydes or ketones react with a secondary amine, formation of enamine takes place. The nitrogen analog of an enol is known as enamine. From the resonating structures of enamine, it is clear that it nucleophilic in nature. Reactivity of enamines is higher than an enol but less than an enolate ion. Milder conditions are favored for enamine reactions.

(b)

Interpretation Introduction

Interpretation:

The given conversion is to be accomplished with the help of enamine synthesis using pyrrolidine as the secondary amine.

Concept introduction:

When aldehydes or ketones react with a secondary amine, formation of enamine takes place. The nitrogen analog of an enol is known as enamine. From the resonating structures of enamine, it is clear that it nucleophilic in nature. Reactivity of enamines is higher than an enol but less than an enolate ion. Milder conditions are favourable for enamine reactions.

(c)

Interpretation Introduction

Interpretation:

The given conversion is to be accomplished with the help of enamine synthesis using pyrrolidine as the secondary amine.

Concept introduction:

When aldehydes or ketones react with a secondary amine, formation of enamine takes place. The nitrogen analog of an enol is known as enamine. From the resonating structures of enamine, it is clear that it nucleophilic in nature. Reactivity of enamines is higher than an enol but less than an enolate ion. Milder conditions are favored for enamine reactions.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 4

Question

Definition Definition Organic compounds that have a carbonyl group, C=O, as their functional group. The carbonyl group in aldehydes is placed at the end of the molecular structure, which means the C=O is attached to one hydrogen atom and an alkyl group or a benzene ring. Just like all the other homologous series in organic chemistry, the naming of aldehydes uses the suffix “-al”. The general molecular formula is C n H 2n O.

Chapter 22.4, Problem 22.9P

(a)

Interpretation Introduction

Interpretation:

The given conversion is to be accomplished with the help of enamine synthesis using pyrrolidine as the secondary amine.

Concept introduction:

When aldehydes or ketones react with a secondary amine, formation of enamine takes place. The nitrogen analog of an enol is known as enamine. From the resonating structures of enamine, it is clear that it nucleophilic in nature. Reactivity of enamines is higher than an enol but less than an enolate ion. Milder conditions are favored for enamine reactions.

(b)

Interpretation Introduction

Interpretation:

The given conversion is to be accomplished with the help of enamine synthesis using pyrrolidine as the secondary amine.

Concept introduction:

When aldehydes or ketones react with a secondary amine, formation of enamine takes place. The nitrogen analog of an enol is known as enamine. From the resonating structures of enamine, it is clear that it nucleophilic in nature. Reactivity of enamines is higher than an enol but less than an enolate ion. Milder conditions are favourable for enamine reactions.

(c)

Interpretation Introduction

Interpretation:

The given conversion is to be accomplished with the help of enamine synthesis using pyrrolidine as the secondary amine.

Concept introduction:

When aldehydes or ketones react with a secondary amine, formation of enamine takes place. The nitrogen analog of an enol is known as enamine. From the resonating structures of enamine, it is clear that it nucleophilic in nature. Reactivity of enamines is higher than an enol but less than an enolate ion. Milder conditions are favored for enamine reactions.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 5

Chapter 22.4, Problem 22.9P

(a)

Interpretation Introduction

Interpretation:

The given conversion is to be accomplished with the help of enamine synthesis using pyrrolidine as the secondary amine.

Concept introduction:

When aldehydes or ketones react with a secondary amine, formation of enamine takes place. The nitrogen analog of an enol is known as enamine. From the resonating structures of enamine, it is clear that it nucleophilic in nature. Reactivity of enamines is higher than an enol but less than an enolate ion. Milder conditions are favored for enamine reactions.

(b)

Interpretation Introduction

Interpretation:

The given conversion is to be accomplished with the help of enamine synthesis using pyrrolidine as the secondary amine.

Concept introduction:

When aldehydes or ketones react with a secondary amine, formation of enamine takes place. The nitrogen analog of an enol is known as enamine. From the resonating structures of enamine, it is clear that it nucleophilic in nature. Reactivity of enamines is higher than an enol but less than an enolate ion. Milder conditions are favourable for enamine reactions.

(c)

Interpretation Introduction

Interpretation:

The given conversion is to be accomplished with the help of enamine synthesis using pyrrolidine as the secondary amine.

Concept introduction:

When aldehydes or ketones react with a secondary amine, formation of enamine takes place. The nitrogen analog of an enol is known as enamine. From the resonating structures of enamine, it is clear that it nucleophilic in nature. Reactivity of enamines is higher than an enol but less than an enolate ion. Milder conditions are favored for enamine reactions.

Answer 6

Chapter 22.4, Problem 22.9P

(a)

Interpretation Introduction

Interpretation:

The given conversion is to be accomplished with the help of enamine synthesis using pyrrolidine as the secondary amine.

Concept introduction:

When aldehydes or ketones react with a secondary amine, formation of enamine takes place. The nitrogen analog of an enol is known as enamine. From the resonating structures of enamine, it is clear that it nucleophilic in nature. Reactivity of enamines is higher than an enol but less than an enolate ion. Milder conditions are favored for enamine reactions.

Answer 7

Chapter 22.4, Problem 22.9P

(a)

Interpretation Introduction

Interpretation:

The given conversion is to be accomplished with the help of enamine synthesis using pyrrolidine as the secondary amine.

Concept introduction:

When aldehydes or ketones react with a secondary amine, formation of enamine takes place. The nitrogen analog of an enol is known as enamine. From the resonating structures of enamine, it is clear that it nucleophilic in nature. Reactivity of enamines is higher than an enol but less than an enolate ion. Milder conditions are favored for enamine reactions.

Answer 8

(b)

Interpretation Introduction

Interpretation:

The given conversion is to be accomplished with the help of enamine synthesis using pyrrolidine as the secondary amine.

Concept introduction:

When aldehydes or ketones react with a secondary amine, formation of enamine takes place. The nitrogen analog of an enol is known as enamine. From the resonating structures of enamine, it is clear that it nucleophilic in nature. Reactivity of enamines is higher than an enol but less than an enolate ion. Milder conditions are favourable for enamine reactions.

Answer 9

(b)

Interpretation Introduction

Interpretation:

The given conversion is to be accomplished with the help of enamine synthesis using pyrrolidine as the secondary amine.

Concept introduction:

When aldehydes or ketones react with a secondary amine, formation of enamine takes place. The nitrogen analog of an enol is known as enamine. From the resonating structures of enamine, it is clear that it nucleophilic in nature. Reactivity of enamines is higher than an enol but less than an enolate ion. Milder conditions are favourable for enamine reactions.

Answer 10

(c)

Interpretation Introduction

Interpretation:

The given conversion is to be accomplished with the help of enamine synthesis using pyrrolidine as the secondary amine.

Concept introduction:

When aldehydes or ketones react with a secondary amine, formation of enamine takes place. The nitrogen analog of an enol is known as enamine. From the resonating structures of enamine, it is clear that it nucleophilic in nature. Reactivity of enamines is higher than an enol but less than an enolate ion. Milder conditions are favored for enamine reactions.

Answer 11

(c)

Interpretation Introduction

Interpretation:

The given conversion is to be accomplished with the help of enamine synthesis using pyrrolidine as the secondary amine.

Concept introduction:

When aldehydes or ketones react with a secondary amine, formation of enamine takes place. The nitrogen analog of an enol is known as enamine. From the resonating structures of enamine, it is clear that it nucleophilic in nature. Reactivity of enamines is higher than an enol but less than an enolate ion. Milder conditions are favored for enamine reactions.

Answer 12

Expert Solution & Answer

Answer 13

Expert Solution & Answer

Answer 14

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 15

Ch. 22.2A - Prob. 22.2P Ch. 22.4 - Without looking back, propose a mechanism for the...Ch. 22.4 - Prob. 22.8P Ch. 22.4 - Prob. 22.9P Ch. 22.5A - Prob. 22.10P Ch. 22.5A - Prob. 22.11P Ch. 22.5B - Prob. 22.12P Ch. 22.5B - Predict the products of the following reactions....Ch. 22.5B - Which compounds will give positive iodoform tests?...Ch. 22.5C - Propose a mechanism for the acid-catalyzed...

Solution Summary: The author explains that aldehydes or ketones react with a secondary amine, formation of enamine takes place.

Want to see the full answer?

Chapter 22 Solutions