The method of preparation of given compound using malonic ester synthesis has to be stated. Concept introduction: Deprotonation of malonic ester give enolate ion. This enolate ion is alkylated by an unhindered alkyl halide , tosylates or any other electrophilic species through S N 2 displacement to give alkylated diethyl malonate. It will undergo hydrolysis to give substituted acetic acid.

Question

Want to see the full answer?

Answer 1

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 22.16, Problem 22.47P

(a)

Interpretation Introduction

Interpretation:

The method of preparation of given compound using malonic ester synthesis has to be stated.

Concept introduction:

Deprotonation of malonic ester give enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through SN2 displacement to give alkylated diethyl malonate. It will undergo hydrolysis to give substituted acetic acid.

(b)

Interpretation Introduction

Interpretation:

The method of preparation of given compound using malonic ester synthesis is to be stated.

Concept introduction:

Deprotonation of malonic ester give enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through SN2 displacement to give alkylated diethyl malonate. It will undergo hydrolysis to give substituted acetic acid.

(c)

Interpretation Introduction

Interpretation:

The method of preparation of given compound using malonic ester synthesis is to be stated.

Concept introduction:

Deprotonation of malonic ester give enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through SN2 displacement to give alkylated diethyl malonate. It will undergo hydrolysis to give substituted acetic acid.

(d)

Interpretation Introduction

Interpretation:

The method of preparation of given compound using malonic ester synthesis is to be stated.

Concept introduction:

Deprotonation of malonic ester give enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through SN2 displacement to give alkylated diethyl malonate. It will undergo hydrolysis to give substituted acetic acid.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

Step 1: add a curved arrow. Select Draw Templates More / " C H Br 0 Br : :o: Erase H H H H Q2Q Step 2: Draw the intermediates and a curved arrow. Select Draw Templates More MacBook Air / " C H Br 0 9 Q Erase 2Q

O Macmillan Learning Question 23 of 26 > Stacked Step 7: Check your work. Does your synthesis strategy give a substitution reaction with the expected regiochemistry and stereochemistry? Draw the expected product of the forward reaction. - - CN DMF MacBook Air Clearly show stereochemistry. Question

NH2 1. CH3–MgCl 2. H3O+ ? As the lead product manager at OrganometALEKS Industries, you are trying to decide if the following reaction will make a molecule with a new C - C bond as its major product: If this reaction will work, draw the major organic product or products you would expect in the drawing area below. If there's more than one major product, you can draw them in any arrangement you like. Be sure you use wedge and dash bonds if necessary, for example to distinguish between major products with different stereochemistry. If the major products of this reaction won't have a new C - C bond, just check the box under the drawing area and leave it blank. Click and drag to start drawing a structure. This reaction will not make a product with a new C - C bond. Х ☐: C

Answer 2

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 22.16, Problem 22.47P

(a)

Interpretation Introduction

Interpretation:

The method of preparation of given compound using malonic ester synthesis has to be stated.

Concept introduction:

Deprotonation of malonic ester give enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through SN2 displacement to give alkylated diethyl malonate. It will undergo hydrolysis to give substituted acetic acid.

(b)

Interpretation Introduction

Interpretation:

The method of preparation of given compound using malonic ester synthesis is to be stated.

Concept introduction:

Deprotonation of malonic ester give enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through SN2 displacement to give alkylated diethyl malonate. It will undergo hydrolysis to give substituted acetic acid.

(c)

Interpretation Introduction

Interpretation:

The method of preparation of given compound using malonic ester synthesis is to be stated.

Concept introduction:

Deprotonation of malonic ester give enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through SN2 displacement to give alkylated diethyl malonate. It will undergo hydrolysis to give substituted acetic acid.

(d)

Interpretation Introduction

Interpretation:

The method of preparation of given compound using malonic ester synthesis is to be stated.

Concept introduction:

Deprotonation of malonic ester give enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through SN2 displacement to give alkylated diethyl malonate. It will undergo hydrolysis to give substituted acetic acid.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 3

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 22.16, Problem 22.47P

(a)

Interpretation Introduction

Interpretation:

The method of preparation of given compound using malonic ester synthesis has to be stated.

Concept introduction:

Deprotonation of malonic ester give enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through SN2 displacement to give alkylated diethyl malonate. It will undergo hydrolysis to give substituted acetic acid.

(b)

Interpretation Introduction

Interpretation:

The method of preparation of given compound using malonic ester synthesis is to be stated.

Concept introduction:

Deprotonation of malonic ester give enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through SN2 displacement to give alkylated diethyl malonate. It will undergo hydrolysis to give substituted acetic acid.

(c)

Interpretation Introduction

Interpretation:

The method of preparation of given compound using malonic ester synthesis is to be stated.

Concept introduction:

Deprotonation of malonic ester give enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through SN2 displacement to give alkylated diethyl malonate. It will undergo hydrolysis to give substituted acetic acid.

(d)

Interpretation Introduction

Interpretation:

The method of preparation of given compound using malonic ester synthesis is to be stated.

Concept introduction:

Deprotonation of malonic ester give enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through SN2 displacement to give alkylated diethyl malonate. It will undergo hydrolysis to give substituted acetic acid.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 4

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 22.16, Problem 22.47P

(a)

Interpretation Introduction

Interpretation:

The method of preparation of given compound using malonic ester synthesis has to be stated.

Concept introduction:

Deprotonation of malonic ester give enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through SN2 displacement to give alkylated diethyl malonate. It will undergo hydrolysis to give substituted acetic acid.

(b)

Interpretation Introduction

Interpretation:

The method of preparation of given compound using malonic ester synthesis is to be stated.

Concept introduction:

Deprotonation of malonic ester give enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through SN2 displacement to give alkylated diethyl malonate. It will undergo hydrolysis to give substituted acetic acid.

(c)

Interpretation Introduction

Interpretation:

The method of preparation of given compound using malonic ester synthesis is to be stated.

Concept introduction:

Deprotonation of malonic ester give enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through SN2 displacement to give alkylated diethyl malonate. It will undergo hydrolysis to give substituted acetic acid.

(d)

Interpretation Introduction

Interpretation:

The method of preparation of given compound using malonic ester synthesis is to be stated.

Concept introduction:

Deprotonation of malonic ester give enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through SN2 displacement to give alkylated diethyl malonate. It will undergo hydrolysis to give substituted acetic acid.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 5

Chapter 22.16, Problem 22.47P

(a)

Interpretation Introduction

Interpretation:

The method of preparation of given compound using malonic ester synthesis has to be stated.

Concept introduction:

Deprotonation of malonic ester give enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through SN2 displacement to give alkylated diethyl malonate. It will undergo hydrolysis to give substituted acetic acid.

(b)

Interpretation Introduction

Interpretation:

The method of preparation of given compound using malonic ester synthesis is to be stated.

Concept introduction:

Deprotonation of malonic ester give enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through SN2 displacement to give alkylated diethyl malonate. It will undergo hydrolysis to give substituted acetic acid.

(c)

Interpretation Introduction

Interpretation:

The method of preparation of given compound using malonic ester synthesis is to be stated.

Concept introduction:

Deprotonation of malonic ester give enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through SN2 displacement to give alkylated diethyl malonate. It will undergo hydrolysis to give substituted acetic acid.

(d)

Interpretation Introduction

Interpretation:

The method of preparation of given compound using malonic ester synthesis is to be stated.

Concept introduction:

Deprotonation of malonic ester give enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through SN2 displacement to give alkylated diethyl malonate. It will undergo hydrolysis to give substituted acetic acid.

Answer 6

Chapter 22.16, Problem 22.47P

(a)

Interpretation Introduction

Interpretation:

The method of preparation of given compound using malonic ester synthesis has to be stated.

Concept introduction:

Deprotonation of malonic ester give enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through SN2 displacement to give alkylated diethyl malonate. It will undergo hydrolysis to give substituted acetic acid.

Answer 7

Chapter 22.16, Problem 22.47P

(a)

Interpretation Introduction

Interpretation:

The method of preparation of given compound using malonic ester synthesis has to be stated.

Concept introduction:

Deprotonation of malonic ester give enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through SN2 displacement to give alkylated diethyl malonate. It will undergo hydrolysis to give substituted acetic acid.

Answer 8

(b)

Interpretation Introduction

Interpretation:

The method of preparation of given compound using malonic ester synthesis is to be stated.

Concept introduction:

Deprotonation of malonic ester give enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through SN2 displacement to give alkylated diethyl malonate. It will undergo hydrolysis to give substituted acetic acid.

Answer 9

(b)

Interpretation Introduction

Interpretation:

The method of preparation of given compound using malonic ester synthesis is to be stated.

Concept introduction:

Deprotonation of malonic ester give enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through SN2 displacement to give alkylated diethyl malonate. It will undergo hydrolysis to give substituted acetic acid.

Answer 10

(c)

Interpretation Introduction

Interpretation:

The method of preparation of given compound using malonic ester synthesis is to be stated.

Concept introduction:

Deprotonation of malonic ester give enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through SN2 displacement to give alkylated diethyl malonate. It will undergo hydrolysis to give substituted acetic acid.

Answer 11

(c)

Interpretation Introduction

Interpretation:

The method of preparation of given compound using malonic ester synthesis is to be stated.

Concept introduction:

Deprotonation of malonic ester give enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through SN2 displacement to give alkylated diethyl malonate. It will undergo hydrolysis to give substituted acetic acid.

Answer 12

(d)

Interpretation Introduction

Interpretation:

The method of preparation of given compound using malonic ester synthesis is to be stated.

Concept introduction:

Deprotonation of malonic ester give enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through SN2 displacement to give alkylated diethyl malonate. It will undergo hydrolysis to give substituted acetic acid.

Answer 13

(d)

Interpretation Introduction

Interpretation:

The method of preparation of given compound using malonic ester synthesis is to be stated.

Concept introduction:

Deprotonation of malonic ester give enolate ion. This enolate ion is alkylated by an unhindered alkyl halide, tosylates or any other electrophilic species through SN2 displacement to give alkylated diethyl malonate. It will undergo hydrolysis to give substituted acetic acid.

Answer 14

Expert Solution & Answer

Answer 15

Expert Solution & Answer

Answer 16

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 17

Ch. 22.2A - Prob. 22.2P Ch. 22.4 - Without looking back, propose a mechanism for the...Ch. 22.4 - Prob. 22.8P Ch. 22.4 - Prob. 22.9P Ch. 22.5A - Prob. 22.10P Ch. 22.5A - Prob. 22.11P Ch. 22.5B - Prob. 22.12P Ch. 22.5B - Predict the products of the following reactions....Ch. 22.5B - Which compounds will give positive iodoform tests?...Ch. 22.5C - Propose a mechanism for the acid-catalyzed...

Solution Summary: The author explains the method of preparation of given compound using malonic ester synthesis.

Want to see the full answer?

Chapter 22 Solutions