ORGANIC CHEMISTRY-PACKAGE >CUSTOM<
ORGANIC CHEMISTRY-PACKAGE >CUSTOM<
10th Edition
ISBN: 9781260028355
Author: Carey
Publisher: MCG CUSTOM
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Chapter 22, Problem 52P
Interpretation Introduction

Interpretation:

The synthesis of N-methyl-4-phenyl-piperidine that shows the necesaary reagents and isolated intermediates is to be shown.

Concept introduction:

The general steps involved in the formation of alcohol from ester are as follows.

The first step is the nucleophilic attack of first equivalent of Grignard reagent.

The second step involves the removal of the leaving group.

The next step is the nucleophilic attack of second equivalent of Grignard reagent.

The last step is the protonation of the intermediate formed above.

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