Microbiology: An Introduction (13th Edition)
13th Edition
ISBN: 9780134605180
Author: Gerard J. Tortora, Berdell R. Funke, Christine L. Case, Derek Weber, Warner Bair
Publisher: PEARSON
expand_more
expand_more
format_list_bulleted
Videos
Textbook Question
Chapter 22, Problem 1R
If Clostridium tetani is relatively sensitive to penicillin, why doesn’t penicillin cure tetanus?
Expert Solution & Answer
Summary Introduction
To review:
Why penicillin does not cure tetanus.
Introduction:
Tetanus is an infectious disease caused by the bacteria named Clostridium tetani. It is a rod-shaped (bacillus), gram-positive, anaerobic, spore-forming bacteria.
Explanation of Solution
The anaerobic bacteria Clostridium tetani is sensitive to penicillin. However, adequate blood flow to the site of infection is necessary for penicillin to attain an optimum concentration at the site and to show maximum effectiveness. The causative pathogen is an obligate anaerobe and the wound by which it enters the body provide them an optimum anaerobic growth condition. Thus, due to the absence of enough blood flow, penicillin does not cure tetanus.
Conclusion
Tetanus infections commonly occur following a puncture wound exposed to the C. tetani bacteria. Contamination of the wound often involves contact with soil, fecal matter, or rusty metal containing the causative pathogen.
Want to see more full solutions like this?
Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!
Students have asked these similar questions
What drugs would you recommend for Tetanus treatment?
Explain the mechanism of action of the toxin from Clostridium botulinum.
How this mechanism can be used for clinical and cosmetic purposes, including treatment of facial wrinkles?
Clostridium botulinum is neutrophile ?
A newly admitted patient reports a penicillin allery. The prescriber has ordered a second-eneration cephalosporin as part of the therapy. Which nursin action is appropriate?a) Call the prescriber to clarify the order because of the patient’s allery.b )Give the medication, and monitor for adverse effects.c) Ask the pharmacy to chane the order to a first-eneration cephalosporin.d )Administer the dru with a nonsteroidal antiinflammatory dru to reduce adverse effects
Chapter 22 Solutions
Microbiology: An Introduction (13th Edition)
Ch. 22 - If Clostridium tetani is relatively sensitive to...Ch. 22 - Prob. 2RCh. 22 - Prob. 3RCh. 22 - Prob. 4RCh. 22 - Prob. 5RCh. 22 - Prob. 6RCh. 22 - Prob. 7RCh. 22 - Prob. 8RCh. 22 - Provide evidence that Creutzfeldt-Jakob disease is...Ch. 22 - NAME IT This organism causes meningitis and is...
Ch. 22 - Prob. 1MCQCh. 22 - Prob. 2MCQCh. 22 - Prob. 3MCQCh. 22 - Prob. 4MCQCh. 22 - Prob. 5MCQCh. 22 - Prob. 6MCQCh. 22 - Prob. 7MCQCh. 22 - Prob. 8MCQCh. 22 - Microscopic examination of cerebrospinal fluid...Ch. 22 - Prob. 10MCQCh. 22 - Prob. 1ACh. 22 - Prob. 2ACh. 22 - Prob. 1CAECh. 22 - Prob. 2CAECh. 22 - Prob. 3CAE
Additional Science Textbook Solutions
Find more solutions based on key concepts
Describe the evolution of mammals, tracing their synapsid lineage from early amniote ancestors to true mammals....
Loose Leaf For Integrated Principles Of Zoology
Single penny tossed 20 times and counting heads and tails: Probability (prediction): _______/20 heads ________/...
Laboratory Manual for Holes Human Anatomy & Physiology Fetal Pig Version
The appearance of glucose in the urine a. occurs normally. b. indicates the presence of kidney disease. c. occu...
Human Physiology
Relative thickness of the myocardium in different chambers; the functional significance of those differences; a...
Anatomy & Physiology: The Unity of Form and Function
The correct term for production of offspring. Introduction: Reproduction is an important life process for most ...
Biology Illinois Edition (Glencoe Science)
What are the cervical and lumbar enlargements?
Principles of Anatomy and Physiology
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- All of the following are true about Clostridium tetani, thecausative agent of tetanus, EXCEPT:(a) They are spore-forming rods.(b) They are part of the normal bowel microflora of horses,cattle, and humans.(c) They produce a powerful exotoxin that mediates thedisease.(d) Their toxin elicits muscle stiffness, spasms, and paralysisin the victim.(e) They require oxygen to survive.arrow_forwardWhy is it clinically important to distinguish S. pneumoniae from otherα-hemolytic streptococci?arrow_forwardBacillus anthracis is the causative agent of anthrax. true or false?arrow_forward
- Which of the following statements about Pasteurella multocida is false?a) Infections generally respond to a penicillin.b) It can cause epidemics of fatal disease in domestic animals.c) It is commonly found in the mouths of biting animals, including humans.d) A vaccine is used to prevent P. multocida disease in people.e) Cat bites are more likely to result in P. multocida infections than dog bites.arrow_forwardWhy do the penicillin and cephalosporin groups of drugs have mildertoxicity than other antibiotics? What are their primary side effects?arrow_forwardExplain why C. tetani can be cultivated from wounds in the absence of tetanus.arrow_forward
- Is Saccharomyces boulardii safe?arrow_forwardWhich of the following about Staphylococcus aureus is false?a) It is generally coagulase-positive.b) Its infectious dose is increased in the presence of foreign material.c) Some strains infecting wounds can cause toxic shock.d) Nasal carriers have an increased the risk of surgical wound infection.e) It is pyogenic.arrow_forwardWhat are some Important facts about staphylococcus capitis? Why are they significant?arrow_forward
- What makes bacterial diseases such as Clostridium botulinum, Clostridium perfringens & Clostridium tetani very effective to cause infection in a human host?arrow_forwardWhich of these statements about tetanus is true?a) It can start from a bee sting.b) Immunization is carried out using tiny doses of killed C. tetani.c) Those who recover from the disease are immune for life.d) Tetanus immune globulin does not prevent the disease.e) It is easy to avoid exposure to spores of the causative organism.arrow_forwardThe clinical features of varicella rash are() A) is densely distributed throughout the body B) Mainly limbs C) Mainly lower limbs and buttocks D) Begins behind the ears,at the neck,along the hairline and develops throughout the body E) Centripetal distributionarrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
Essentials of Pharmacology for Health ProfessionsNursingISBN:9781305441620Author:WOODROWPublisher:Cengage
Essentials of Pharmacology for Health Professions
Nursing
ISBN:9781305441620
Author:WOODROW
Publisher:Cengage
The Human Reproductive System; Author: Professor Dave Explains;https://www.youtube.com/watch?v=TucxiIB76bo;License: Standard YouTube License, CC-BY