GENERAL,ORGANIC,+BIO.CHEM.-MINDTAP
7th Edition
ISBN: 9781305866966
Author: STOKER
Publisher: CENGAGE L
expand_more
expand_more
format_list_bulleted
Concept explainers
Question
Chapter 21.10, Problem 1QQ
Interpretation Introduction
Interpretation:
The area in which inhibition of angiotensin-converting enzyme by the medication lisinopril is useful has to be predicted.
Concept Introduction:
Angiotensin is an octapeptide which is involved in the regulation of blood pressure. Untill needed, it is present in an inactive form as the zymogen angiotensinogen. Angiotensin-converting enzyme (ACE) converts the inactive zymogen to the active octapeptide form (angiotensin).
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solutionStudents have asked these similar questions
High concentration of glucose 6-phosphate is inhibitory to ____. (I) Hexokinase (II) Pyruvate kinase (III) Glucokinase(IV) Phosphofructoskinase-1
Select one:
a. (I) only
b. (I) and (III) only
c. (III) only
d. (III) and (IV) only
Part A
What is the main difference between a hormone and a vitamin?
O A vitamin is usually an enzyme cofactor, whereas a hormone regulates enzyme activity.
O A hormone is usually an enzyme cofactor, whereas a vitamin regulates enzyme activity.
Submit
Request Answer
Provide Feedback
A non-reactive substrate analogue has been found to inhibit a
target enzyme. Modifying the inhibitor to make it more like TS
(‡) will? (Select All that Apply)
a. Make it a better inhibitor
b. Make it a worse inhibitor
c. Make it bind tighter
d. Make it bind weaker
e. Increase the KD
f. Decrease the KD
Chapter 21 Solutions
GENERAL,ORGANIC,+BIO.CHEM.-MINDTAP
Ch. 21.1 - Which of the following statements concerning the...Ch. 21.1 - Prob. 2QQCh. 21.2 - Which of the following statements about a...Ch. 21.2 - Which of the following statements about cofactors...Ch. 21.2 - Prob. 3QQCh. 21.3 - Which of the following statements concerning an...Ch. 21.3 - Prob. 2QQCh. 21.3 - Which of the following pairings of enzyme type and...Ch. 21.3 - Which of the following pairings of enzyme type and...Ch. 21.4 - Prob. 1QQ
Ch. 21.4 - Which of the following statements concerning the...Ch. 21.4 - Prob. 3QQCh. 21.5 - The specificity of an enzyme that catalyzes the...Ch. 21.5 - Prob. 2QQCh. 21.6 - The number of substrate molecules converted to...Ch. 21.6 - Prob. 2QQCh. 21.6 - Prob. 3QQCh. 21.7 - Extremozyme presence is not possible in which of...Ch. 21.7 - Prob. 2QQCh. 21.8 - Prob. 1QQCh. 21.8 - Prob. 2QQCh. 21.8 - Prob. 3QQCh. 21.9 - Prob. 1QQCh. 21.9 - Prob. 2QQCh. 21.9 - Prob. 3QQCh. 21.10 - Prob. 1QQCh. 21.10 - Prob. 2QQCh. 21.11 - Prob. 1QQCh. 21.11 - Prob. 2QQCh. 21.12 - Prob. 1QQCh. 21.12 - Prob. 2QQCh. 21.12 - Prob. 3QQCh. 21.13 - Prob. 1QQCh. 21.13 - Prob. 2QQCh. 21.13 - In the recharging of a metal-containing enzyme by...Ch. 21.14 - Prob. 1QQCh. 21.14 - Prob. 2QQCh. 21.14 - Prob. 3QQCh. 21.14 - Which of the B vitamins has a name that draws...Ch. 21.14 - Prob. 5QQCh. 21.14 - Prob. 6QQCh. 21.15 - Prob. 1QQCh. 21.15 - Prob. 2QQCh. 21.15 - Prob. 3QQCh. 21.15 - For which of the following vitamins is blood...Ch. 21.15 - Prob. 5QQCh. 21 - What is the general role of enzymes in the human...Ch. 21 - Why does the body need so many different enzymes?Ch. 21 - Prob. 21.3EPCh. 21 - Prob. 21.4EPCh. 21 - Indicate whether each of the following phrases...Ch. 21 - Indicate whether each of the following phrases...Ch. 21 - Explain why a metal ion can function as a cofactor...Ch. 21 - Prob. 21.8EPCh. 21 - Prob. 21.9EPCh. 21 - Indicate whether each of the following statements...Ch. 21 - Prob. 21.11EPCh. 21 - Based on its name, indicate whether each of the...Ch. 21 - Predict the function of each of the following...Ch. 21 - Predict the function of each of the following...Ch. 21 - Prob. 21.15EPCh. 21 - Prob. 21.16EPCh. 21 - Prob. 21.17EPCh. 21 - Suggest a name for an enzyme that catalyzes each...Ch. 21 - Prob. 21.19EPCh. 21 - Prob. 21.20EPCh. 21 - To which of the six major classes of enzymes does...Ch. 21 - To which of the six major classes of enzymes does...Ch. 21 - Identify the enzyme needed in each of the...Ch. 21 - Identify the enzyme needed in each of the...Ch. 21 - Prob. 21.25EPCh. 21 - Indicate whether each of the following statements...Ch. 21 - Indicate whether each of the statements in Problem...Ch. 21 - Indicate whether each of the statements in Problem...Ch. 21 - Prob. 21.29EPCh. 21 - Prob. 21.30EPCh. 21 - Prob. 21.31EPCh. 21 - Prob. 21.32EPCh. 21 - Indicate whether each of the following statements...Ch. 21 - Indicate whether each of the following statements...Ch. 21 - Prob. 21.35EPCh. 21 - Prob. 21.36EPCh. 21 - Prob. 21.37EPCh. 21 - Prob. 21.38EPCh. 21 - What type of specificity (absolute, group,...Ch. 21 - What type of specificity (absolute, group,...Ch. 21 - The following graph shows the relationship between...Ch. 21 - Based on the graphical information in Problem...Ch. 21 - Prob. 21.43EPCh. 21 - Based on the graphical information in Problem...Ch. 21 - Prob. 21.45EPCh. 21 - Prob. 21.46EPCh. 21 - Draw a graph that shows the effect of increasing...Ch. 21 - Prob. 21.48EPCh. 21 - Prob. 21.49EPCh. 21 - What is an enzyme turnover number?Ch. 21 - Describe the effect that each of the following...Ch. 21 - Describe the effect that each of the following...Ch. 21 - What is an extremophile?Ch. 21 - What are two common environmental settings where...Ch. 21 - Indicate whether each of the following pairings of...Ch. 21 - Indicate whether each of the following pairings of...Ch. 21 - Prob. 21.57EPCh. 21 - What type(s) of extremophiles are used in oil well...Ch. 21 - Prob. 21.59EPCh. 21 - Prob. 21.60EPCh. 21 - Prob. 21.61EPCh. 21 - Indicate whether each of the following statements...Ch. 21 - Prob. 21.63EPCh. 21 - Indicate whether each of the following statements...Ch. 21 - Prob. 21.65EPCh. 21 - Indicate whether each of the following statements...Ch. 21 - Prob. 21.67EPCh. 21 - Prob. 21.68EPCh. 21 - Prob. 21.69EPCh. 21 - Prob. 21.70EPCh. 21 - Prob. 21.71EPCh. 21 - Prob. 21.72EPCh. 21 - Prob. 21.73EPCh. 21 - Prob. 21.74EPCh. 21 - Prob. 21.75EPCh. 21 - Prob. 21.76EPCh. 21 - Prob. 21.77EPCh. 21 - Prob. 21.78EPCh. 21 - Prob. 21.79EPCh. 21 - Prob. 21.80EPCh. 21 - Prob. 21.81EPCh. 21 - Prob. 21.82EPCh. 21 - What is the medical diagnostic value associated...Ch. 21 - Prob. 21.84EPCh. 21 - Indicate whether each of the following is a...Ch. 21 - Indicate whether each of the following is a...Ch. 21 - Prob. 21.87EPCh. 21 - Prob. 21.88EPCh. 21 - Prob. 21.89EPCh. 21 - Prob. 21.90EPCh. 21 - Prob. 21.91EPCh. 21 - What are the structural differences between the...Ch. 21 - Prob. 21.93EPCh. 21 - Prob. 21.94EPCh. 21 - Vitamin C is biosynthesized in a two-step process....Ch. 21 - Prob. 21.96EPCh. 21 - Prob. 21.97EPCh. 21 - Prob. 21.98EPCh. 21 - Prob. 21.99EPCh. 21 - Prob. 21.100EPCh. 21 - Which of the B vitamins has a structure that fits...Ch. 21 - Which of the B vitamins has a structure that fits...Ch. 21 - Prob. 21.103EPCh. 21 - Prob. 21.104EPCh. 21 - Prob. 21.105EPCh. 21 - Prob. 21.106EPCh. 21 - The coenzyme forms of B vitamins are involved in...Ch. 21 - The coenzyme form of B vitamins are involved in...Ch. 21 - Prob. 21.109EPCh. 21 - What is the relationship between the plant pigment...Ch. 21 - Prob. 21.111EPCh. 21 - List four major functions of vitamin A in the...Ch. 21 - Prob. 21.113EPCh. 21 - Prob. 21.114EPCh. 21 - Prob. 21.115EPCh. 21 - Prob. 21.116EPCh. 21 - Prob. 21.117EPCh. 21 - Prob. 21.118EPCh. 21 - Prob. 21.119EPCh. 21 - Prob. 21.120EPCh. 21 - Which structural form of vitamin E exhibits the...Ch. 21 - Prob. 21.122EPCh. 21 - Prob. 21.123EPCh. 21 - Prob. 21.124EPCh. 21 - Prob. 21.125EPCh. 21 - Prob. 21.126EPCh. 21 - Prob. 21.127EPCh. 21 - Prob. 21.128EPCh. 21 - Prob. 21.129EPCh. 21 - Prob. 21.130EPCh. 21 - Prob. 21.131EPCh. 21 - Which vitamin or vitamins has (have) each of the...Ch. 21 - Which of the 13 vitamins has a structure that fits...Ch. 21 - Prob. 21.134EP
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.Similar questions
- HO, N' Steric effect A) Present B) Absentarrow_forward1) This a model for what type of inhibitor? a) Competitive b) Uncompetitive c) Mixed d) Pure noncompetitive e) All of the above f) None of the abovearrow_forwardA patient who has been successfully receiving gentamycin for the past 2 weeks suddenly develops renal conditions and a decreased GFR. What adjustment to the dosage should be done? Question 7 options: A) discontinue the drug B) increase the dosage C) increase the time interval between doses D) coadminister phenobarbital to stimulate liver metabolism E) no adjustment neededarrow_forward
- Questi Listen A patient with which of the following conditions would have to be cautious when taking beta blockers? A) Diabetes mellitus (DM) B) Irritable bowel syndrome (IBS) C) Chronic urinary tract infection (UTI) OD) Rheumatoid arthritis (RA)arrow_forward31. The graph shows the effects of the inhibitor captopril (cprl) on the conversion of angiotensin I to angiotensin II by angiotensin- converting enzyme (ACE). Doubling the amount of captopril in the assay will result in which of the following changes in the values of Km for angiotensin I and the Vmax for ACE? A) B) C) D) E) F) G) ↑ ↑ ↑ No change V max ↑ ↓ no change no change no change 1/ 64286 - 40 - 20 16 14 12- 10--- 8- 6 4. cprl c prl 0 20 40 60 80 1/ [angiotensin I (mM)]arrow_forwardNonearrow_forward
- The complete hydrolysis of a protein yields what as products? a. amino acids b. dipeptides c. monosaccharides d. glucose molecules e. no correct response givenarrow_forward22. According to the lock-and-key theory of enzyme behavior, which of the following can be thought of as the key? a. enzyme b. substrate с. ароenzyme d. coenzyme e. no correct responsearrow_forwardIdentify the isotopes that would be found in each metabolite when [2-¹4C, ¹5N]glutamate undergoes oxidative degradation in the liver of a rat. urea succinate arginine citrulline ornithine aspartate 000000 Answer Bank 15 N 14C I COO- H-15N+- -14℃ H H _________ CH₂ COO- Labeled glutamatearrow_forward
- Drugs called COX-2 inhibitors (e.g., Vioxx, Bextra, andCelebrex) were thought to relieve the pain and inflammation ofosteoarthritis without the stomach bleeding and ulcers non-steroidal anti-inflammatory drugs (NSAIDs) cause. In a 12-month trial, Vioxx caused fewer gastrointestinal side effectsthan the NSAID ibuprofen. However, a study of the recurrenceof colon polyps after three years of Vioxx found an increasedrisk for heart attack and stroke beginning after 18 months oftreatment. As a result, Vioxx was withdrawn from the market,and an FDA panel concluded that COX-2 inhibitors as a classhave increased cardiovascular risk that varies by drug anddose. The FDA then caused the withdrawal of Bextra and re-quired a warning label on Celebrex. Based on this information,list (a) an observation, (b) a hypothesis, (c) an experiment, and(d) a theory.arrow_forward1arrow_forward24. In the following diagram, the rate of an enzyme-catalyzed reaction is graphed on the y (or vertical) axis versus another quantity on the x axis. What quantity is graphed on the x axis? a. substrate concentration Ob. reaction pH Oc. reaction temperature Od. more than one response is correct e. no correct responsearrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- Introduction to General, Organic and BiochemistryChemistryISBN:9781285869759Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar TorresPublisher:Cengage LearningChemistry for Today: General, Organic, and Bioche...ChemistryISBN:9781305960060Author:Spencer L. Seager, Michael R. Slabaugh, Maren S. HansenPublisher:Cengage Learning
Introduction to General, Organic and Biochemistry
Chemistry
ISBN:9781285869759
Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher:Cengage Learning
Chemistry for Today: General, Organic, and Bioche...
Chemistry
ISBN:9781305960060
Author:Spencer L. Seager, Michael R. Slabaugh, Maren S. Hansen
Publisher:Cengage Learning
Lipids - Fatty Acids, Triglycerides, Phospholipids, Terpenes, Waxes, Eicosanoids; Author: The Organic Chemistry Tutor;https://www.youtube.com/watch?v=7dmoH5dAvpY;License: Standard YouTube License, CC-BY