The activity of RNA polymerase II is inhibited by Actinomycin D. When actinomycin D is present, early development in many vertebrate species, for example frogs, can begin after the formation of a blastula (hollow ball of cells that forms after early cleavage divisions), but development stops before gastrulation. Question asked to discuss the activity of maternal gene in contrast to activity of zygotic gene in early frog development. Introduction: Drosophila is the model organism of study of development. It is a well studied genome sequence. Multiple genes are involved in the development of drosophila. The gene that directs the development and fate of an organism are known as developmental genes. Bicoid and Nanos are maternal effect genes; the egg receives these from the mother. Bicoid and Nanos play an important role in creating the anterior to posterior axis. The genes are activated in the fertilized egg (Zygote). In contrast to maternal effect genes, these genes are transcribed by zygotic DNA.

Question

Want to see the full answer?

Answer 1

Question

Chapter 20, Problem 9P

Summary Introduction

To analyze:

The activity of RNA polymerase II is inhibited by Actinomycin D. When actinomycin D is present, early development in many vertebrate species, for example frogs, can begin after the formation of a blastula (hollow ball of cells that forms after early cleavage divisions), but development stops before gastrulation. Question asked to discuss the activity of maternal gene in contrast to activity of zygotic gene in early frog development.

Introduction:

Drosophila is the model organism of study of development. It is a well studied genome sequence. Multiple genes are involved in the development of drosophila. The gene that directs the development and fate of an organism are known as developmental genes. Bicoid and Nanos are maternal effect genes; the egg receives these from the mother. Bicoid and Nanos play an important role in creating the anterior to posterior axis. The genes are activated in the fertilized egg (Zygote). In contrast to maternal effect genes, these genes are transcribed by zygotic DNA.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

Our understanding of maternal effect genes has been greatly aided by their identification in experimental organisms such as Drosophila melanogaster and Caenorhabditis elegans. In experimental organisms with a short generation time, geneticists have successfully searched for mutant alleles that prevent the normal process of embryonic development. In many cases, the offspring die at early embryonic or larval stages. These are called maternal effect lethal alleles. How would a researcher identify a mutation that produced a recessive maternal effect lethal allele?

Using a transgenic technique, propose an experiment to determine whether Cdx2 is sufficient for trophoblast development in the mouse embryo. Describe two results that you would expect to observe at the blastocyst stage if Cdx2 is indeed sufficient for trophoblast development. Be as specific as possible regarding the transgene that you propose for this experiment (including what gene's enhancer you would use in the transgene). Note: you do not need to explain the details of how a transgenic mouse is made. Describe the experiment in steps (Step 1: ..., Step 2: ... etc) and please keep your answer to under 150 words. tips: DONT talk about stop cassetes/memory cassetes, focus on transgenes Paper called "Cdx2 is required for correct cell fate specification and differentiation of trophectoderm in the mouse blastocyst" gave lots of results that you might see,, 6 diff ways that cdx2 is required for trophoblasts need specific gene enhancer (dont just say "expressed enhancer in genital…

White eyes in Drosophila melanogaster result from an X-linked recessive mutation. Occasionally, white-eyed mutants give rise to offspring that possess white eyes with small red spots. The number, distribution, and size of the red spots are variable. Explain how a transposable element could be responsible for this spotting phenomenon.