Microbiology: An Introduction
12th Edition
ISBN: 9780321929150
Author: Gerard J. Tortora, Berdell R. Funke, Christine L. Case
Publisher: PEARSON
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Textbook Question
Chapter 20, Problem 1MCQ
Which of the following pairs is mismatched?
- a. antihelminthic—inhibition of oxidative phosphorylation
- b. antihelminthic—inhibition of cell wall synthesis
- c. antifungal—injury to plasma membrane
- d. antifungal—inhibition of mitosis
- e. antiviral—inhibition of DNA synthesis
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Whether an antimicrobial is broad spectrum or narrow spectrum depends on its
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Chapter 20 Solutions
Microbiology: An Introduction
Ch. 20 - DRAW IT Show where the following antibiotics work:...Ch. 20 - List and explain five criteria used to identify an...Ch. 20 - What similar problems are encountered with...Ch. 20 - Define drug resistance. How is it produced? What...Ch. 20 - List the advantages of using two chemotherapeutic...Ch. 20 - Why does a cell die from the following...Ch. 20 - How does each of the following inhibit...Ch. 20 - The OH is missing from carbon 39 in ddI. How does...Ch. 20 - Compare the method of action of the following...Ch. 20 - NAME IT This microorganism is not susceptible to...
Ch. 20 - Which of the following pairs is mismatched? a....Ch. 20 - Prob. 2MCQCh. 20 - Prob. 3MCQCh. 20 - An antimicrobial agent should meet all of the...Ch. 20 - The most selective antimicrobial activity would be...Ch. 20 - Prob. 6MCQCh. 20 - Which of the following will not affect eukaryotic...Ch. 20 - Cell membrane damage causes death because a. the...Ch. 20 - A drug that intercalates into DNA has the...Ch. 20 - Chloramphenicol binds to the 50S portion of a...Ch. 20 - Prob. 1ACh. 20 - Why is idoxuridine effective if host cells also...Ch. 20 - Some bacteria become resistant to tetracycline...Ch. 20 - The following data were obtained from a...Ch. 20 - Prob. 5ACh. 20 - The following results were obtained from a broth...Ch. 20 - Vancomycin-resistant Enterococcus faecalis was...Ch. 20 - Prob. 2CAECh. 20 - Prob. 3CAE
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- See picture-- match microbial drug to its action. There can be more than one action per drug.arrow_forwardA major problem in fighting pathogenic bacteria is known as the 'antiseptic dilemma'. Explain what this "dilemma" is, why it's a problem, and how antibiotics like penicillin avoid this problem.arrow_forwardWhich of the following modes of action would be most selectively toxic?a. interrupting ribosomal functionb. dissolving the cell membranec. preventing cell wall synthesisd. inhibiting DNA replicationarrow_forward
- Which of the following is NOT a property of an antimicrobial agent? a. Must have a known concentration over a period of time required to eliminate a pathogen b. all choices are correct c. must be selectively toxic d. Must have a favorable chemotherapeutic indexarrow_forwardMany antibiotics used in modern medicine are compounds made by fungi that inhibit bacterial protein synthesis. Describe the specific effect of the following antimicrobial drugs: (i) Chloramphenicol (ii) Rifamycinarrow_forwardYears ago, uncouplers were suggested to make wonderful diet drugs. Explain why this idea was proposed and why it was rejected. Why might the producers of antiperspirants be supportive of the idea?arrow_forward
- What is the mode of action of most antifungal drugs? inhibition of RNA synthesis disruption of membranes destruction of chitin inhibition of protein synthesis inhibition of folic acid precursor synthesisarrow_forwardThe type of antimicrobial drug that would be most likely to have toxic effects in humans based on the premise of selective toxicity when treating microbial infection would be a drug that O 1) inhibits the synthesis of the cell wall O 2) inhibits metabolic pathways O 3) disrupts the cytoplasmic membrane 4) inhibits protein synthesis 5) All of the above have equal potential to be toxicarrow_forwardThe statements are given below, which will best describe why antimicrobial drugs that affect cell wall synthesis tend to have selective toxicity when used by humans? Human cells only synthesize peptidoglycan as a food source Cell wall synthesis is a common metabolic process in humans and bacteria. Most bacteria only synthesize cell walls during their log phase of growth. Human cells do not have cell walls.arrow_forward
- what is the mechanism of action for penicillins? a. injury to plasma membrane b. inbibition of protein synthesis c. inhibition of cell wall synhesis d. inhibition of nucleic acid synthesis e. none of the above describes the mechanism of action for penicillinsarrow_forwardDefine the following terms: a. turnover b. cyt P450 c. detoxication d. detoxification e. epoxidearrow_forwardChoose the combination of answers that most accurately completes the statement.Which of the following modes of action would be most selectively toxic? a. interrupting ribosomal function b. dissolving the cell membrane c. preventing cell wall synthesis d. inhibiting DNA replicationarrow_forward
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