Microbiology: An Introduction
12th Edition
ISBN: 9780321929150
Author: Gerard J. Tortora, Berdell R. Funke, Christine L. Case
Publisher: PEARSON
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Chapter 20, Problem 6MCQ
Summary Introduction
Introduction:
Though protein synthesis is done by both prokaryotic and eukaryotic cells, they differ in the structure of ribosome. The prokaryotic cells have 70S ribosomes, whereas the eukaryotic cells contain 80S ribosomes. The mitochondrial ribosome in the eukaryotic cells possess 70S ribosomes similar to the bacterial cells.
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1)You add a drug to cells that can pass through hydrophilic or hydrobic environments (e.g., membranes & cytosol). The drug specifically prevents the binding of KDEL (ER retention signal) to any other molecules. In the short term, what would happen to the synthesis and localization of translocon proteins?
a. New complete translocon proteins would be made, but they would end up in the golgi apparatus.
b. New complete translocon proteins would be made, but they would end up at the plasma membrane
c. No new intact translocon proteins would be synthesized
d. New complete translocon proteins would be made, but they would be secreted
e. New complete translocon proteins would be made and localized normally
Which of the following is true of ribosome rescue? (C & E wrong)
A. The process produces a protein that is tagged for degradation.
B. Proteases enter the A-site of the ribosome to degrade the C-terminus of the synthesized peptide.
C. A partially translated mRNA becomes fully degraded before it can be translated further.
D. No protein is produced in the process.
E. Stalled ribosomes are released in the absence of a stop codon.
All of the following regarding ribosomes are true EXCEPT:
A. Ribosomes are comprised of protein and RNA.
B. Ribosomes coordinate with initiation and elongation factors to regulate translation.
C. Ribosomes bind transcripts in their promoters.
D. Prokaryotic ribosomes are comprised of a large and a small subunit.
E. Ribosomes in eukaryotic cells bind to complete transcripts.
Chapter 20 Solutions
Microbiology: An Introduction
Ch. 20 - DRAW IT Show where the following antibiotics work:...Ch. 20 - List and explain five criteria used to identify an...Ch. 20 - What similar problems are encountered with...Ch. 20 - Define drug resistance. How is it produced? What...Ch. 20 - List the advantages of using two chemotherapeutic...Ch. 20 - Why does a cell die from the following...Ch. 20 - How does each of the following inhibit...Ch. 20 - The OH is missing from carbon 39 in ddI. How does...Ch. 20 - Compare the method of action of the following...Ch. 20 - NAME IT This microorganism is not susceptible to...
Ch. 20 - Which of the following pairs is mismatched? a....Ch. 20 - Prob. 2MCQCh. 20 - Prob. 3MCQCh. 20 - An antimicrobial agent should meet all of the...Ch. 20 - The most selective antimicrobial activity would be...Ch. 20 - Prob. 6MCQCh. 20 - Which of the following will not affect eukaryotic...Ch. 20 - Cell membrane damage causes death because a. the...Ch. 20 - A drug that intercalates into DNA has the...Ch. 20 - Chloramphenicol binds to the 50S portion of a...Ch. 20 - Prob. 1ACh. 20 - Why is idoxuridine effective if host cells also...Ch. 20 - Some bacteria become resistant to tetracycline...Ch. 20 - The following data were obtained from a...Ch. 20 - Prob. 5ACh. 20 - The following results were obtained from a broth...Ch. 20 - Vancomycin-resistant Enterococcus faecalis was...Ch. 20 - Prob. 2CAECh. 20 - Prob. 3CAE
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- Which of the following BEST describes the characteristics and function of siRNA? A. a short strand of RNA that can complement and inactivate a sequence of mRNA B. a short strand of RNA that can act as a transcription factor to initiate transcription C. a strand of DNA that can bind to and inactivate an mRNA sequence D. a tRNA that is not able to attach to a ribosome and therefore inhibits the process of translationarrow_forwardHypertrophic cardiomyopathy is caused by mutations in the β-myosin heavy chain gene. One common mutation involves a change of an arginine (Arg) to a glutamine (Gln) at position 403. Using the genetic code shown above, what could the sequence of the mutant codon be? a. CAA b. CGA c. CGG d. CACarrow_forwardAntisense therapeutics are important because: Select one: O a. They only act at the ribosome O b. They can be easily delivered to their sight of activity after systemic administration They can be found in large quantities in the Golgi O c. O d. They hybridise to the antisense strand of a DNA transcript Oe. They are being use as a routinely administered medicine Ribozymes are good candidates as molecular therapeutics because Select one: O a. They are more stable than DNA is body fluids Ob. They can easily cross biological barriers with out the aid of a drug delivery system Oc. They retain secondary structure that may point to an evolutionary link between RNA and protei They are more stable than many proteins in body fluids They can be encoded into a plasmid and delivered as a DNA based construct give both answer only with little bit explanation Asap Thanks d. O e.arrow_forward
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