Microbiology: An Introduction
12th Edition
ISBN: 9780321929150
Author: Gerard J. Tortora, Berdell R. Funke, Christine L. Case
Publisher: PEARSON
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Textbook Question
Chapter 20, Problem 3A
Some bacteria become resistant to tetracycline because they don’t make porins. Why can a porin-deficient mutant be detected by its inability to grow on a medium containing a single carbon source such as succinic acid?
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Type S Streptococcus pneumoniae bacterium is lethal and will kill its host. If heat inactivated the S strain dies and becomes nonlethal. Type R Streptococcus pneumoniae is a nonvirulent strain of bacteria. What would occur if one were to inject both the R strain and heat-killed S strains into a host organism such as the mouse?
The R strain would be transformed into the virulent S strain and kill the host.
Neither the S nor the R strain would change.
The R strain would be transformed into the virulent S strain and not affect the host.
The S strain would be transformed into the nonvirulent R strain and not affect the host
The S strain would be transformed into the nonvirulent R strain and kill the host.
The ribosome is the target for many important antibiotics. These drugs must discriminate between bacterial and eukaryotic ribosomes to achieve drug specificity and toxicity. For the two common antibiotics below, what is their mechanism of action and why are they more toxic to bacteria than eukaryotes?
a) Tetracycline
b) Erythromycin
You have isolated a strain of E.coli that is resistant to penicillin,streptomycin,chloramphenicol and tetracycline. You also observe that when you mix this strain with a strain that is sensitive to all four antibiotics, the new strain becomes resistant to streptomycin,penicillin and chloramphenicol but not tetracycline. Explain how this is so?
Chapter 20 Solutions
Microbiology: An Introduction
Ch. 20 - DRAW IT Show where the following antibiotics work:...Ch. 20 - List and explain five criteria used to identify an...Ch. 20 - What similar problems are encountered with...Ch. 20 - Define drug resistance. How is it produced? What...Ch. 20 - List the advantages of using two chemotherapeutic...Ch. 20 - Why does a cell die from the following...Ch. 20 - How does each of the following inhibit...Ch. 20 - The OH is missing from carbon 39 in ddI. How does...Ch. 20 - Compare the method of action of the following...Ch. 20 - NAME IT This microorganism is not susceptible to...
Ch. 20 - Which of the following pairs is mismatched? a....Ch. 20 - Prob. 2MCQCh. 20 - Prob. 3MCQCh. 20 - An antimicrobial agent should meet all of the...Ch. 20 - The most selective antimicrobial activity would be...Ch. 20 - Prob. 6MCQCh. 20 - Which of the following will not affect eukaryotic...Ch. 20 - Cell membrane damage causes death because a. the...Ch. 20 - A drug that intercalates into DNA has the...Ch. 20 - Chloramphenicol binds to the 50S portion of a...Ch. 20 - Prob. 1ACh. 20 - Why is idoxuridine effective if host cells also...Ch. 20 - Some bacteria become resistant to tetracycline...Ch. 20 - The following data were obtained from a...Ch. 20 - Prob. 5ACh. 20 - The following results were obtained from a broth...Ch. 20 - Vancomycin-resistant Enterococcus faecalis was...Ch. 20 - Prob. 2CAECh. 20 - Prob. 3CAE
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