Microbiology: An Introduction
12th Edition
ISBN: 9780321929150
Author: Gerard J. Tortora, Berdell R. Funke, Christine L. Case
Publisher: PEARSON
expand_more
expand_more
format_list_bulleted
Videos
Textbook Question
Chapter 20, Problem 9MCQ
A drug that intercalates into DNA has the following effects. Which one leads to the others?
- a. It disrupts transcription.
- b. It disrupts translation.
- c. It interferes with
DNA replication. - d. It causes mutations.
- e. It alters proteins.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
Which of the following statements about our defenses to protect DNA are correct (select all that apply)?
A.
Genetic differences in GST enzymes may affect risk of cancer
B.
Reactive Oxygens species that damage DNA are removed by catalase
C.
On average, humans are exposed to more naturally occurring plant pesticides compared to man made pesticides.
D.
Cancer cells upregulate concentration of Glutathione S-Transferase (GST) to remove electrophilic compounds
E.
High levels of melanin are correlated with increased risk of skin cancer
If you were going to design a drug to fight a virus, what would be likely targets for the drug design?
Which of the following pathways is likely to NOT be directly affected by the antimetabolite drug methotrexate?
a. Production of purine deoxyribonucleotides
b. Production of purine ribonucleotides
c. Production of thymidylate
d. Production of pyrimidine ribonucleotides
Chapter 20 Solutions
Microbiology: An Introduction
Ch. 20 - DRAW IT Show where the following antibiotics work:...Ch. 20 - List and explain five criteria used to identify an...Ch. 20 - What similar problems are encountered with...Ch. 20 - Define drug resistance. How is it produced? What...Ch. 20 - List the advantages of using two chemotherapeutic...Ch. 20 - Why does a cell die from the following...Ch. 20 - How does each of the following inhibit...Ch. 20 - The OH is missing from carbon 39 in ddI. How does...Ch. 20 - Compare the method of action of the following...Ch. 20 - NAME IT This microorganism is not susceptible to...
Ch. 20 - Which of the following pairs is mismatched? a....Ch. 20 - Prob. 2MCQCh. 20 - Prob. 3MCQCh. 20 - An antimicrobial agent should meet all of the...Ch. 20 - The most selective antimicrobial activity would be...Ch. 20 - Prob. 6MCQCh. 20 - Which of the following will not affect eukaryotic...Ch. 20 - Cell membrane damage causes death because a. the...Ch. 20 - A drug that intercalates into DNA has the...Ch. 20 - Chloramphenicol binds to the 50S portion of a...Ch. 20 - Prob. 1ACh. 20 - Why is idoxuridine effective if host cells also...Ch. 20 - Some bacteria become resistant to tetracycline...Ch. 20 - The following data were obtained from a...Ch. 20 - Prob. 5ACh. 20 - The following results were obtained from a broth...Ch. 20 - Vancomycin-resistant Enterococcus faecalis was...Ch. 20 - Prob. 2CAECh. 20 - Prob. 3CAE
Additional Science Textbook Solutions
Find more solutions based on key concepts
True or false? Some trails are considered vestigial because they existed long ago.
Biological Science
Describe the role and impact of microbes on the earth.
Microbiology Fundamentals: A Clinical Approach - Standalone book
a. What three lineages of lobe-fins survive today? b. Go back to the phylogenetic tree in Interactive Question ...
Study Guide for Campbell Biology
How does the removal of hydrogen atoms from nutrient molecules result in a loss of energy from the nutrient mol...
Seeley's Anatomy & Physiology
Describe the evolution of mammals, tracing their synapsid lineage from early amniote ancestors to true mammals....
Loose Leaf For Integrated Principles Of Zoology
Consider the experiment described in Section 2.1 in which Ted Garland and colleagues bred mice to run long dist...
Evolutionary Analysis (5th Edition)
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Which of the following best describes the mechanism of action of the antibiotic streptomycin? A. it disrupts protein synthesis in resistant bacteria. B. Streptomycin inhibits cell wall synthesis in all bacterial species. C. Streptomycin creates mutations in bacteria which cause them to become resistant. D. It disrupts protein synthesis in nonresistant bacteria.arrow_forwardUltraviolet (UV) radiation is damaging because it A. Prevents Translation B. Causes Mutation in the DNA C. Prevents DNA Transcription D. Causes Proein Synthesisarrow_forwardIn the discovery of new drugs, the chemical and physical properties of a molecule are very important to be determined. All of the following are physical and chemical properties that are important in drug discovery EXCEPT….A. route of administrationB. fat/water partitionC. molecular steric hindranceD. pHE. pKa Secretion of acid ions from gastric acid, is one of the drug distribution processes by...A. Passive diffusion with facilitiesB. passive diffusionC. dissolves in lipids that make up the membraneD. pinocytosisE. active diffusionarrow_forward
- You would like to create an anti-viral medication that is active against both H5N2 and H5N1 strains of influenza. The best drug target would be: a. ribosomal protein production b. Hemagglutinin-mediated fusion c. Neuroaminidase-mediated buddingarrow_forwardA.) There is no change in the DNA sequence if nucleotides are added or removed, it will have no effect to the cell. B.) Mutations in the DNA sequence are all irreversible. A. Statement A is correct B. Statement B is correct C. Both A and B are correct D. Both A and B are incorrectarrow_forwardThe following statements apply to compounds to which HONO, benzo(a)pyrene, aflatoxin, formaldehyde and chloroform are examples of: A. All may alter DNA sequences because they alkylate nucleotide bases B. All may alter DNA sequences which could result in altered protein products. C. All are mutagenic because they intercalate DNA D. All are mutagenic and causes the production of apurinic sites O E. All are mutagenic because they cause substitution of a base resulting in the production of a protein product with altered sequencearrow_forward
- What are the important types MRNA molecule or genetic sequence that you can target to design a drug? Don't copy paste your answer from websites... Use your own answersarrow_forwardRetroviruses such as HIV, Herpesviruses, and Hepatitis B can be effectively inhibited by _____. Mark all that apply: A. inhibition of cell wall synthesis B. inhibition of ergosterol C. disruption of the ETS in infected cells D. nucleoside analogs such as acyclovirarrow_forwardwhich of the following can be used to stimulate an organism's immune system? A. Restriction Enzymes B. DNA Ligase C. Sticky Ends D. Monoclonal Antibodiesarrow_forward
- Scientists from the first successful drug trial to reduce concentrations of huntingtin reported that the drug is not a cure for Huntington's disease. Suggest two reasons why the drug should not be considered a cure. Do not include repeats of the drug trial in your answer.arrow_forwardDefine the following terms:a. tumor promoterb. guanine nucleotide exchange factorc. DAGd. steady statee. IP3arrow_forwardFinding drugs to treat viruses is far more challenging than finding drugs to treat bacteria. A. Why the difference? Ans: Viruses need a host cell to replicate and a bacteria needs food to continue to replicate. B. What can anti-viral drugs target in order to bring a viral infection under control, or to prevent a viral infection in the first place? Ans: To bring an infection under control you would want to inhibit protease so it could not break down the polypeptide protein chain down into new protein coats. C. What can anti-viral drugs target to prevent a viral infection in the first place? Ans: To prevent a viral infection in the first place you could take a medication that would alter the surface receptor, fill in the surface receptor or inhibits the viral surface protein all together. D. Offer 2 examples of drugs used to control viral infections (specify virus) and how do they work on different targets. Ans:…arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSON
Biology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStax
Anatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & Company
Laboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:PEARSON
Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax
Anatomy & Physiology
Biology
ISBN:9781259398629
Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:9780815344322
Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:9781260159363
Author:Martin, Terry R., Prentice-craver, Cynthia
Publisher:McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Biology
ISBN:9781260231700
Author:Sylvia S. Mader, Michael Windelspecht
Publisher:McGraw Hill Education
USMLE-Rx Antimicrobial Therapy; Author: USMLE-Rx;https://www.youtube.com/watch?v=Pka1Ynlrqtw;License: Standard Youtube License