Pearson eText Microbiology: An Introduction -- Instant Access (Pearson+)
13th Edition
ISBN: 9780135789377
Author: Gerard Tortora, Berdell Funke
Publisher: PEARSON+
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Textbook Question
Chapter 20, Problem 10MCQ
Chloramphenicol binds to the 50S portion of a ribosome, which will interfere with
- a. transcription in prokaryotic cells.
- b. transcription in eukaryotic cells.
- c. translation in prokaryotic cells.
- d. translation in eukaryotic cells.
- e. DNA synthesis.
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All of the following regarding ribosomes are true EXCEPT:
A. Ribosomes are comprised of protein and RNA.
B. Ribosomes coordinate with initiation and elongation factors to regulate translation.
C. Ribosomes bind transcripts in their promoters.
D. Prokaryotic ribosomes are comprised of a large and a small subunit.
E. Ribosomes in eukaryotic cells bind to complete transcripts.
Define the following terms:a. decoding centerb. peptidyl transferase centerc. GTPase-associated centerd. guanine nucleotide exchange factore. proton shuttle mechanism
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a. Adenosine-5'-triphosphate
b. Uridine-5'-monophosphate
c. Deoxythymidine-5'-monophosphate
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e. Deoxyadenosine
Chapter 20 Solutions
Pearson eText Microbiology: An Introduction -- Instant Access (Pearson+)
Ch. 20 - DRAW IT Show where the following antibiotics work:...Ch. 20 - List and explain five criteria used to identify an...Ch. 20 - What similar problems are encountered with...Ch. 20 - Define drug resistance. How is it produced? What...Ch. 20 - List the advantages of using two chemotherapeutic...Ch. 20 - Why does a cell die from the following...Ch. 20 - How does each of the following inhibit...Ch. 20 - The OH is missing from carbon 39 in ddI. How does...Ch. 20 - Compare the method of action of the following...Ch. 20 - NAME IT This microorganism is not susceptible to...
Ch. 20 - Which of the following pairs is mismatched? a....Ch. 20 - Prob. 2MCQCh. 20 - Prob. 3MCQCh. 20 - An antimicrobial agent should meet all of the...Ch. 20 - The most selective antimicrobial activity would be...Ch. 20 - Prob. 6MCQCh. 20 - Which of the following will not affect eukaryotic...Ch. 20 - Cell membrane damage causes death because a. the...Ch. 20 - A drug that intercalates into DNA has the...Ch. 20 - Chloramphenicol binds to the 50S portion of a...Ch. 20 - Prob. 1ACh. 20 - Why is idoxuridine effective if host cells also...Ch. 20 - Some bacteria become resistant to tetracycline...Ch. 20 - The following data were obtained from a...Ch. 20 - Prob. 5ACh. 20 - The following results were obtained from a broth...Ch. 20 - Vancomycin-resistant Enterococcus faecalis was...Ch. 20 - Prob. 2CAECh. 20 - Prob. 3CAE
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- Translation can be regulated by a. translational repressors. b. antisense RNA. c. attenuation. d. both a and b.arrow_forwardThis molecule is most likely implicated in the renaturation of proteins. Select one: a. chaperone (HSP) b. kinase c. RISC d. proteasome e. transcriptional factorarrow_forwardWhich of the following is true of ribosome rescue? (C & E wrong) A. The process produces a protein that is tagged for degradation. B. Proteases enter the A-site of the ribosome to degrade the C-terminus of the synthesized peptide. C. A partially translated mRNA becomes fully degraded before it can be translated further. D. No protein is produced in the process. E. Stalled ribosomes are released in the absence of a stop codon.arrow_forward
- Which of the following statements is/are TRUE about the difference between prokaryotic and eukaryotic translations? A. The chain elongation step is the most different process. B. Eukaryotes have less elongation factors than in prokaryotes. C. The release factors in prokaryotes can bind to all three stop codons. D. The fMet and Met are the 1st amino acid in prokaryotes and eukaryotes, respectively.arrow_forwardThe primary function of RF1 during translation is to: a. recognize a stop codon in the 70S A site during termination. b. recognize the start codon in the 70S P site during initiation. c. move tRNAs and mRNA through the ribosome during elongation. d. facilitate binding of the ribosome to mRNA during initiation.arrow_forwardEach of the following statements about protein synthesis is false.Correct each to make a true statement. a. In a gene, each nucleotide specifies one amino acid in a protein sequence. b. A transcription factor must bind to the promoter region of a gene before the enzyme DNA synthetase is able to bind and begin transcription. c. The enzyme RNA polymerase builds a strand of transfer RNA, whose codons are complementary to DNA’s triplets. d. Proteins destined for secretion from the cell enter the nucleus after translation, to be folded and modified. e. During translation, amino acids are delivered by the messenger RNA transcriparrow_forward
- Which of the following is TRUE in translation? A. Amino acyl TRNA containing one amino acid is attached to the P site B. Amino acids/peptides attached to the amino acyl tRNA at the P site are transferred to amino acids at the A site, followed by translocation. C. Empty TRNAS are immediately released from the ribosomes D. The E site is always empty after translocation to receive incoming empty TRNAS. E. The anticodon binding to the codon is stringent, i.e. there must be complete complementary base-pairing between the bases in the codon and anticodon before translation can proceed.arrow_forwardHistone deacetylase (HDAC) enzymes a.Promote initiation of translation. b.Complex with hyperphosphorylated pRb. c.Repress E2F family activity. d.Add acetyl groups to E2F promoters. e.Promote initiation of transcription.arrow_forwardWhich of the following steps in protein synthesis does not require a direct supply of energy? a. proofreading step by certain aminoacyl-tRNA synthetases b. translocation of mRNA in a ribosome c. linkage of an amino acid to its cognate tRNA d. alignment of a tRNA anticodon with an mRNA codonarrow_forward
- Which of the following is/are required in the amino acid activation by aminoacyl-tRNA synthetase? A. tRNA B. Mg2+ C. GTP D. mRNA E. amino acid F. ATP G. rRNAarrow_forwardThe Kozak rules determine a. the choice of the start codon in complex eukaryotes. b. the choice of the start codon in bacteria. c. the site in the mRNA where translation ends. d. how fast the mRNA is translated.arrow_forwardWhich of the following is true about the genetic code? A. A codon is three to six bases long. B. Each amino acid is specified by only one codon. C. The codon signaling the end of transcription also codes for an amino acid. D. There are multple codons signaling the start of transcription. E. All organisms use essentially the same genetic code.arrow_forward
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