Pearson eText Microbiology: An Introduction -- Instant Access (Pearson+)
13th Edition
ISBN: 9780135789377
Author: Gerard Tortora, Berdell Funke
Publisher: PEARSON+
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Textbook Question
Chapter 20, Problem 1MCQ
Which of the following pairs is mismatched?
- a. antihelminthic—inhibition of oxidative phosphorylation
- b. antihelminthic—inhibition of cell wall synthesis
- c. antifungal—injury to plasma membrane
- d. antifungal—inhibition of mitosis
- e. antiviral—inhibition of DNA synthesis
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Whether an antimicrobial is broad spectrum or narrow spectrum depends on its
mode of action. For the following 2 hypothetical drugs, predict whether they are
broad spectrum or narrow spectrum. Explain your reasoning:
4.
a. Drug A interferes with peptidoglycan synthesis -
b. Drug B interferes with 70S ribosome function-
c. Drug C interferes with synthesis of a vitamin –
Match these drugs with the following functions
Cell wall synthesis inhibitors
50s Ribosomal subunit inhibitors
Anti-metabolite
Cell Membrane disrupters
DNA synthesis inhibitor
30s Ribosomal subunit inhibitors
See picture-- match microbial drug to its action. There can be more than one action per drug.
Chapter 20 Solutions
Pearson eText Microbiology: An Introduction -- Instant Access (Pearson+)
Ch. 20 - DRAW IT Show where the following antibiotics work:...Ch. 20 - List and explain five criteria used to identify an...Ch. 20 - What similar problems are encountered with...Ch. 20 - Define drug resistance. How is it produced? What...Ch. 20 - List the advantages of using two chemotherapeutic...Ch. 20 - Why does a cell die from the following...Ch. 20 - How does each of the following inhibit...Ch. 20 - The OH is missing from carbon 39 in ddI. How does...Ch. 20 - Compare the method of action of the following...Ch. 20 - NAME IT This microorganism is not susceptible to...
Ch. 20 - Which of the following pairs is mismatched? a....Ch. 20 - Prob. 2MCQCh. 20 - Prob. 3MCQCh. 20 - An antimicrobial agent should meet all of the...Ch. 20 - The most selective antimicrobial activity would be...Ch. 20 - Prob. 6MCQCh. 20 - Which of the following will not affect eukaryotic...Ch. 20 - Cell membrane damage causes death because a. the...Ch. 20 - A drug that intercalates into DNA has the...Ch. 20 - Chloramphenicol binds to the 50S portion of a...Ch. 20 - Prob. 1ACh. 20 - Why is idoxuridine effective if host cells also...Ch. 20 - Some bacteria become resistant to tetracycline...Ch. 20 - The following data were obtained from a...Ch. 20 - Prob. 5ACh. 20 - The following results were obtained from a broth...Ch. 20 - Vancomycin-resistant Enterococcus faecalis was...Ch. 20 - Prob. 2CAECh. 20 - Prob. 3CAE
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- A major problem in fighting pathogenic bacteria is known as the 'antiseptic dilemma'. Explain what this "dilemma" is, why it's a problem, and how antibiotics like penicillin avoid this problem.arrow_forwardWhich of the following is NOT a property of an antimicrobial agent? a. Must have a known concentration over a period of time required to eliminate a pathogen b. all choices are correct c. must be selectively toxic d. Must have a favorable chemotherapeutic indexarrow_forwardMany antibiotics used in modern medicine are compounds made by fungi that inhibit bacterial protein synthesis. Describe the specific effect of the following antimicrobial drugs: (i) Tetracycline (ii) Puromycin (iii) Alpha-Amanitinarrow_forward
- Many antibiotics used in modern medicine are compounds made by fungi that inhibit bacterial protein synthesis. Describe the specific effect of the following antimicrobial drugs: (i) Chloramphenicol (ii) Rifamycinarrow_forwardYears ago, uncouplers were suggested to make wonderful diet drugs. Explain why this idea was proposed and why it was rejected. Why might the producers of antiperspirants be supportive of the idea?arrow_forwardHCl is involved in a. All of the above b. antimicrobial activity. | c. protein denaturation. O d.D cell activation. e. pepsin activation.arrow_forward
- What is the mode of action of most antifungal drugs? inhibition of RNA synthesis disruption of membranes destruction of chitin inhibition of protein synthesis inhibition of folic acid precursor synthesisarrow_forwardThe type of antimicrobial drug that would be most likely to have toxic effects in humans based on the premise of selective toxicity when treating microbial infection would be a drug that O 1) inhibits the synthesis of the cell wall O 2) inhibits metabolic pathways O 3) disrupts the cytoplasmic membrane 4) inhibits protein synthesis 5) All of the above have equal potential to be toxicarrow_forwardMycotoxins are also medical concerns. How are mycotoxins different from toxins produced by other microorganisms? Cite examples.arrow_forward
- Considering having the same targets, Which of the following inhibitors are correctly grouped? A. Amytal, antimycin A, oligomycin B. Cyanide, amytal, rotenon C. Oligomycin, antimycin A, piericidine D. Carbon monoxide, azide cyanidearrow_forwardWhich of the following is not an inhibitor? a. CO b. Magnesium ion c. sulfa drugs d. cyanide e. penicilinarrow_forwardMatch these drugs from these functions Cell wall synthesis inhibitors 50s Ribosomal subunit inhibitors Anti-metabolite Cell Membrane disrupters DNA synthesis inhibitor 30s Ribosomal subunit inhibitorsarrow_forward
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