EBK HUMAN PHYSIOLOGY
15th Edition
ISBN: 9781260163049
Author: Fox
Publisher: MCGRAW HILL BOOK COMPANY
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Chapter 19, Problem 4RA
Summary Introduction
To determine:
The role of thyroxine hormone.
Introduction:
The thyroid gland is a bilobed organ in which the two lobes are joined together by a structure called isthmus. This is an endocrine gland which releases three hormones, including thyroxine. Thyroxine is secreted by the thyroid follicles within the thyroid gland that targets all the organs of the body.
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Digoxin: Intravenous Bolus - Two Compartment Model
Drug
Digoxin
Route:
IV Bolus
Dose:
0.750 mg
Plasma Concentration Time Profile
Beta
Alpha
Time (hrs)
Conc (ng/ml)
LN
(ng/ml)
LN
(ng/ml)
LN
0.00
#NUM!
#NUM!
#NUM!
0.10
12.290
2.509
#NUM!
#NUMI
0.60
6.975
1.942
#NUM!
#NUMI
1.00
4.649
1.537
#NUM!
#NUMI
2.00
2.201
0.789
#NUM!
#NUM!
3.00
1.536
0.429
#NUM!
#NUM!
4.00
1.342
0.294
#NUM!
#NUM!
5.00
1.273
0.241
#NUM!
#NUMI
6.00
1.238
0.213
#NUM!
#NUM!
7.00
1.212
0.192
#NUM!
#NUM!
8.00
1.188
0.172
#NUMI
#NUM!
9.00
1.165
0.153
#NUM!
#NUMI
10.00
1.143
0.134
#NUMI
#NUM!
11.00
1.122
0.115
#NUM!
12.00
1.101
0.096
#NUMI
13.00
1.080
0.077
#NUMI
16.00
1.020
0.020
#NUMI
24.00
0.876
-0.132
#NUMI
Pharmacokinetic Parameters
Parameter
Value
Alpha
B
Beta
Units
ng/ml
hr-1
ng/ml
hr-1
CO
ng/ml
H.C
AUC
ng x hr/ml
Vc
Vbeta
Vss
C
L/hr
TK (alpha)
hr
TX (beta)
days
5+
F3
F4
F5
0+
F6
F7
%
6
95
14
#3
29
&
t
F8
F9
FW
EW
Chapter 19 Solutions
EBK HUMAN PHYSIOLOGY
Ch. 19 - Explain how the metabolic rate is influenced by...Ch. 19 - Prob. 2aCPCh. 19 - Prob. 2bCPCh. 19 - Prob. 3CPCh. 19 - Distinguish between the energy reserves and...Ch. 19 - Prob. 5CPCh. 19 - Identify the brain regions involved in hunger and...Ch. 19 - Prob. 7CPCh. 19 - Describe how the secretions of insulin and...Ch. 19 - Prob. 8bCP
Ch. 19 - Define the following terms: glycogenolysis,...Ch. 19 - Prob. 9CPCh. 19 - Prob. 10aCPCh. 19 - Prob. 10bCPCh. 19 - Explain the meaning of the terms insulin...Ch. 19 - Prob. 12aCPCh. 19 - Prob. 12bCPCh. 19 - Prob. 13aCPCh. 19 - Prob. 13bCPCh. 19 - Describe the mechanisms by which the secretion of...Ch. 19 - Prob. 15aCPCh. 19 - Prob. 15bCPCh. 19 - Prob. 15cCPCh. 19 - ln questions 1-5, match the item to the correct...Ch. 19 - Prob. 2RACh. 19 - Prob. 3RACh. 19 - Prob. 4RACh. 19 - Prob. 5RACh. 19 - Prob. 6RACh. 19 - Prob. 7RACh. 19 - Prob. 8RACh. 19 - Prob. 9RACh. 19 - The increased intestinal absorption of calcium is...Ch. 19 - Prob. 11RACh. 19 - Prob. 12RACh. 19 - Prob. 13RACh. 19 - Prob. 14RACh. 19 - Prob. 15RACh. 19 - Prob. 16RACh. 19 - Prob. 17RACh. 19 - Prob. 18RACh. 19 - Prob. 19RACh. 19 - Prob. 20RACh. 19 - Prob. 21RACh. 19 - Prob. 22RACh. 19 - Prob. 23RACh. 19 - Prob. 24RACh. 19 - Prob. 25RACh. 19 - Prob. 26RACh. 19 - Prob. 27RACh. 19 - Describe the conditions of gigantism, acromegaly,...Ch. 19 - Describe how hormones secreted by the...Ch. 19 - Prob. 30RACh. 19 - Prob. 31RACh. 19 - Prob. 32RACh. 19 - Prob. 33RACh. 19 - Prob. 34RACh. 19 - Prob. 35RACh. 19 - Prob. 36RACh. 19 - Prob. 37RACh. 19 - Prob. 38RACh. 19 - Prob. 39RACh. 19 - Prob. 40RACh. 19 - Prob. 41RACh. 19 - Prob. 42RACh. 19 - Prob. 43RA
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