Chapter 19, Problem 19.71AP

Interpretation Introduction

Interpretation:

The way by which covalent modification modifies an enzyme to make it more active or more inactive should be determined.

Concept introduction:

Enzyme:

• It is a protein or a molecule which can act as a catalyst for a biological reaction.
• Does not affect the equilibrium point of the reaction.
• Active site of the enzyme is the region where the reaction takes place.
• Enzyme’s activity can be specific which means the activity is limited to a certain substrate and a certain type of reaction and it is referred to as specificity of the enzyme.

Enzyme regulation:

Some enzymes can destroy the organ in which they are produced and they are often synthesized as proenzymes or zymogens.

Enzyme regulation by covalent modification can be done by two methods and one is through removal of a covalently bonded portion of an enzyme or addition of a group.