The way to distinguish between a competitive inhibitor and an uncompetitive inhibitor experimentally should be given. Concept Introduction: Enzyme inhibitors: The substance which slows or stops the action of an enzyme is called enzyme inhibitors. It can be used as drugs and an example is AZT which is used to treat HIV. The competition of an enzyme can be reversible or irreversible and in reversible inhibition, the inhibitor can leave and in irreversible inhibition, the inhibitor remains permanently bound. Reversible Competitive inhibition: It is a type of inhibition occurs when the inhibitor resembles very much to the substrate and thus prevents the substrate binding. Reversible uncompetitive inhibition: It is a type of enzyme regulation in which an inhibitor binds reversibly to the enzyme-substrate complex and thereby blocking the binding of the second substrate to the binding site. Irreversible competitive inhibition: It is a type of inhibition in which an inhibitor forms covalent bonds to the active site and thereby permanently blocking it.

Question

Want to see the full answer?

Answer 1

Question

Chapter 19, Problem 19.83CP

Interpretation Introduction

Interpretation:

The way to distinguish between a competitive inhibitor and an uncompetitive inhibitor experimentally should be given.

Concept Introduction:

Enzyme inhibitors: The substance which slows or stops the action of an enzyme is called enzyme inhibitors.

It can be used as drugs and an example is AZT which is used to treat HIV.

The competition of an enzyme can be reversible or irreversible and in reversible inhibition, the inhibitor can leave and in irreversible inhibition, the inhibitor remains permanently bound.

Reversible Competitive inhibition: It is a type of inhibition occurs when the inhibitor resembles very much to the substrate and thus prevents the substrate binding.

Reversible uncompetitive inhibition: It is a type of enzyme regulation in which an inhibitor binds reversibly to the enzyme-substrate complex and thereby blocking the binding of the second substrate to the binding site.

Irreversible competitive inhibition: It is a type of inhibition in which an inhibitor forms covalent bonds to the active site and thereby permanently blocking it.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

Here is my literature Beta Carotene HPLC analysis graph. Can you help me explain what each peak is at each retention time? Thank You :D

I have a literature B-Carotene HPLC graph in which showcases a retention time of roughly 23.6 and 25.1. Please help me compare my two different Anti-Oxidant Juice graphs. (Attached) The juices provided are: V8 Carrot Ginger Blend and V8 Original Blend Noticing the HPLC graphs I saw no peaks for the Original Blend for B-Carotene. However the Carrot Ginger Blend showed similar peaks --> Why is this reason? Please explain in terms of Retention time and Area (Under Curve). Thank You!

Calculate pH of a solution prepared by dissolving 1.60g of sodium acetate, in 88.5 mL of 0.10 M acetic acid. Assume the volume change upon dissolving the sodium acetate is negligible. Ka is 1.75 x 10^-5