
Concept explainers
Interpretation:
The mechanism for the given conversion has to be proposed.
Concept introduction: When two molecules of an ester undergo condensation is called claisen condensation. Like in aldol reaction, in claisen condensation one molecule is a nucleophile and the other molecule is an electrophile.
A claisen condensation reaction is a reversible reaction and occurs in the presence of a strong base.
The first step of claisen condensation is the removal of a proton from alpha carbon by a base and then the addition of enolate ion formed to the second ester molecule forming a β-ketoester.
A crossed-claisen condensation is also a condensation reaction between a

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Chapter 19 Solutions
ORGANIC CHEMISTRY-OWL V2 ACCESS
- The compound in the figure is reacted with 10 n-butyllihium, 2° propanone, and 3º H2O. Draw and name the products obtained. SiMe3arrow_forwardCaffeine (C8H10N4O2, pictured below) is a weak base. The pKb of caffeine is 10.4. What is the pH of a 0.0155 M solution of caffeine?arrow_forward2-Cyclopentyl-2-methyl-1,3-dioxolane is reacted with H₂SO₄. Draw and name the structures of the products.arrow_forward
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- Please help me solve number 2arrow_forwardChoose the best reagents to complete the following reaction. 오 Na2Cr2O7 H2SO4, H2O Problem 22 of 35 A Na2Cr2O7 H2SO4, H2O H2/Pt B pressure OH 1. NaBH4 C 2. H3O+ D DMP (Dess-Martin Periodinane) CH2Cl2 CrO3 Done Dramabana_Minor Submitarrow_forwardIndicate the products of the reaction of Cycloheptanone with pyrrolidine (cat. H+). Draw the structures of the compounds.arrow_forward
- Indicate the products of the reaction of 2-(3-aminopropyl)cyclohexan-1-one with H2SO4. Draw the structures of the compounds.arrow_forwardIndicate the products of the reaction of 2-cyclopentyl-2-methyl-1,3-dioxolane with H3O+. Draw the structures of the compounds.arrow_forwardQuestion 4 For the molecule shown below, (7 marks): A) Sketch the Newman projection for the view looking along the bond from the perspective of the arrow. B) Then, draw the Newman projection for each 60° rotation along the bond until it returns to the starting point. C) Clearly indicate which Newman projection is the one we see in the structure shown below, and clearly indicate which Newman projection is the highest in energy and which is the lowest in energy. H H Me 'H Me Mearrow_forward
- Organic ChemistryChemistryISBN:9781305580350Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. FootePublisher:Cengage LearningOrganic Chemistry: A Guided InquiryChemistryISBN:9780618974122Author:Andrei StraumanisPublisher:Cengage Learning


