MOLECULAR BIOLOGY OF THE CELL
6th Edition
ISBN: 9780393870947
Author: ALBERTS
Publisher: NORTON
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Chapter 19, Problem 10P
Summary Introduction
To explain: The way in which the αIIbβ3 integrin is held in its inactive state.
Concept introduction: Integrins are transmembrane adhesion proteins that are present as anchoring junctions between cell and the matrix as actin-linked cell–matrix junction. The affinity of these integrins is possible to modify if their cytoplasmic domains are altered, a process called as inside-out signaling.
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19. On the diagram below
a. Label the three pictures as: DNA; polypeptide; or RNA.
b. Label the arrows as: translation or transcription/RNA processing.
c. Add the following details to the diagram.
Promoter region
TATA box
Transcription start site
Transcription terminator
Intron (A,B,C,D)
Exons (1,2,3,4,5)
Splice sites
5' cap
5' UTR (untranslated region)
3' poly A tail
3' UTR (untranslated region)
Translational start (AUG)
Translational stop (UGA, UAG, or UAA)
N and C ends of polypeptide
0000
Match the letter labels in the figure below to the terms. Some letter
labels are not used.
MNNNNNNIN
M
C
B
A
M
D
F
E
H
K
G
8
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