MOLECULAR BIOLOGY OF THE CELL
6th Edition
ISBN: 9780393870947
Author: ALBERTS
Publisher: NORTON
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Chapter 1, Problem 1P
Summary Introduction
To examine: Whether the given statement, “each member of the human hemoglobin gene family, which consists of seven genes arranged in two clusters on different chromosomes, is an ortholog to all the other members” is true or false.
Introduction:
Orthologous and paralogous genes are the type of homologous genes that descended from a common DNA ancestral sequence. Orthologous genes follow the
Expert Solution & Answer
Answer to Problem 1P
Correct answer: The statement is false.
Explanation of Solution
The human α- and β-globin gene families are arranged in a cluster. Each member in the cluster of hemoglobin gene family has exact DNA sequences. They arose by duplication from an ancient ancestral gene during evolution. Thus, they are classified as paralogous genes. These globin genes are orthologous to globin genes of other species.
Hence, the given statement is false.
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