Organic Chemistry, Loose-leaf Version
Organic Chemistry, Loose-leaf Version
8th Edition
ISBN: 9781305865549
Author: William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher: Cengage Learning
Question
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Chapter 18.9, Problem 18.8P

(a)

Interpretation Introduction

Interpretation:

The way by which the given alcohol is prepared by treating an ester with a Grignard reagent has to be shown.

Concept introduction:

Alkyl or aryl magnesium halides (RMgX) are known as Grignard reagent. The Grignard reaction is an organometallic chemical reaction in which the Grignard reagent act as nucleophile and attack electrophilic carbon atom that are present within polar bonds to yield a carbon-carbon bond

Reaction of Grignard reagent with a formic ester followed by hydrolysis in aqueous acid yields secondary alcohol. Tertiary alcohol can be prepared by the reaction of Grignard reagent with ester.

Organic Chemistry, Loose-leaf Version, Chapter 18.9, Problem 18.8P , additional homework tip  1

Organic Chemistry, Loose-leaf Version, Chapter 18.9, Problem 18.8P , additional homework tip  2

(b)

Interpretation Introduction

Interpretation:

The way by which the given alcohol is prepared by treating an ester with a Grignard reagent has to be shown.

Concept introduction:

Alkyl or aryl magnesium halides (RMgX) are known as Grignard reagent. The Grignard reaction is an organometallic chemical reaction in which the Grignard reagent act as nucleophile and attack electrophilic carbon atom that are present within polar bonds to yield a carbon-carbon bond

Reaction of Grignard reagent with a formic ester followed by hydrolysis in aqueous acid yields secondary alcohol. Tertiary alcohol can be prepared by the reaction of Grignard reagent with ester other than formate.

Organic Chemistry, Loose-leaf Version, Chapter 18.9, Problem 18.8P , additional homework tip  3

Organic Chemistry, Loose-leaf Version, Chapter 18.9, Problem 18.8P , additional homework tip  4

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Chapter 18 Solutions

Organic Chemistry, Loose-leaf Version

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