Biochemistry: Concepts and Connections (2nd Edition)
Biochemistry: Concepts and Connections (2nd Edition)
2nd Edition
ISBN: 9780134641621
Author: Dean R. Appling, Spencer J. Anthony-Cahill, Christopher K. Mathews
Publisher: PEARSON
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Chapter 18, Problem 1P
Interpretation Introduction

Interpretation:

The additional substrates, product and coenzyme for the given reaction in the given imaginary pathways should be identified.

Concept Introduction:

Substrates is the molecules or substances where the enzyme acts in a chemical reaction. These chemical reactions containing the substrates catalyze the enzymes.

Molecules which help the enzyme to catalyze in a chemical reaction are called coenzymes.

Product is the molecule or the substance formed during the chemical reaction.

Expert Solution & Answer
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Explanation of Solution

In the given imaginary pathway, the following steps are followed to identify substrates products and coenzymes.

Step 1: The chemical reaction starts with isomerisation where the alignement of molecules change being the same molecule. Here, it is achieved by 5-deoxyadenosyl-B12.

Step 2: Tetrahydrofolate is used to detach aldehyde group in the molecule.

Step 3: The glutamine alone with ATP coverts the carboxylic acid to amide functional group.

Step 4: a ketoglutarate and pyridoxal phosphate is needed to convert amino group to oxygen.

Step 5: With the use of S-adenosylmethionine, the amino group is converted to primary amine.

Thus, the substrates, products and coenzymes are identified by following a few steps in the chemical reaction.

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