Biochemistry: Concepts and Connections (2nd Edition)
Biochemistry: Concepts and Connections (2nd Edition)
2nd Edition
ISBN: 9780134641621
Author: Dean R. Appling, Spencer J. Anthony-Cahill, Christopher K. Mathews
Publisher: PEARSON
Question
Book Icon
Chapter 18, Problem 2P
Interpretation Introduction

(a) Interpretation:

Substrate required by B enzyme should be identified.

Concept Introduction:

Biosynthesis of vitamin B12 or cobalamin has aerobic and anaerobic pathways. Aerobic is where the chemical pathway needs oxygen and later cobalt is added. In anaerobic pathway, cobalt is added in the beginning and requires no oxygen.Biosynthesis of B12 as shown in the diagram produces 5-methyltetrahydrofolate as substrate. And methylmalonate is the compound formed in genetic deficient animal's urine. When the C enzyme loses its affinity towards a substrate injecting large amount of Vitamin B12 is reduced. Homocysteine is released during urine excretion.

Interpretation Introduction

(b) Interpretation:

Compound excreted in urine because ofenzyme C deficiency in animals should be identified.

Concept Introduction:

Biosynthesis of vitamin B12 or cobalamin has aerobic and anaerobic pathways. Aerobic is where the chemical pathway needs oxygen and later cobalt is added. In anaerobic pathway, cobalt is added in the beginning and requires no oxygen. Biosynthesis of B12 as shown in the diagram produces 5-methyltetrahydrofolate as substrate. And methylmalonate is the compound formed in genetic deficient animal's urine. When the C enzyme loses its affinity towards a substrate injecting large amount of Vitamin B12 is reduced. Homocysteine is released during urine excretion.

Interpretation Introduction

(c) Interpretation:

Consistent alterations of genetic in the enzyme because of treatment by injecting B12 for the enzyme C deficiency in animals should be identified.

Concept Introduction:

Biosynthesis of vitamin B12 or cobalamin has aerobic and anaerobic pathways. Aerobic is where the chemical pathway needs oxygen and later cobalt is added. In anaerobic pathway, cobalt is added in the beginning and requires no oxygen. Biosynthesis of B12 as shown in the diagram produces 5-methyltetrahydrofolate as substrate. And methylmalonate is the compound formed in genetic deficient animal's urine. When the C enzyme loses its affinity towards a substrate injecting large amount of Vitamin B12 is reduced. Homocysteine is released during urine excretion.

Interpretation Introduction

(d) Interpretation:

Kinds of amino acid released during urine excretion of animals having genetic deficiency in animals should be identified.

Concept Introduction:

Biosynthesis of vitamin B12 or cobalamin has aerobic and anaerobic pathways. Aerobic is where the chemical pathway needs oxygen and later cobalt is added. In anaerobic pathway, cobalt is added in the beginning and requires no oxygen. Biosynthesis of B12 as shown in the diagram produces 5-methyltetrahydrofolate as substrate. And methylmalonate is the compound formed in genetic deficient animal's urine. When the C enzyme loses its affinity towards a substrate injecting large amount of Vitamin B12 is reduced. Homocysteine is released during urine excretion.

Blurred answer
Students have asked these similar questions
Biochemistry What is the process of "transamination" in either the muscles or the liver, that involves keto acid or glutamic acid? Please explain how the steps work. Thank you!
Biochemistry Please help. Thank you What is the importance of glutamic acid in the metabolism of nitrogen from amino acids? (we know therole; it’s used to remove the nitrogen from amino acids so that the remaining carbon skeleton can bebroken down by the “usual” pathways, but what is the important, unique role that only glutamicacid/glutamate can do?)
Biochemistry Please help. Thank you When carbamyl phosphate is joined to L-ornathine, where does the energy for the reaction come from?
Knowledge Booster
Background pattern image
Similar questions
SEE MORE QUESTIONS
Recommended textbooks for you
Text book image
Biochemistry
Biochemistry
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:W. H. Freeman
Text book image
Lehninger Principles of Biochemistry
Biochemistry
ISBN:9781464126116
Author:David L. Nelson, Michael M. Cox
Publisher:W. H. Freeman
Text book image
Fundamentals of Biochemistry: Life at the Molecul...
Biochemistry
ISBN:9781118918401
Author:Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher:WILEY
Text book image
Biochemistry
Biochemistry
ISBN:9781305961135
Author:Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher:Cengage Learning
Text book image
Biochemistry
Biochemistry
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Cengage Learning
Text book image
Fundamentals of General, Organic, and Biological ...
Biochemistry
ISBN:9780134015187
Author:John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. Peterson
Publisher:PEARSON