Biochemistry: Concepts and Connections (2nd Edition)
Biochemistry: Concepts and Connections (2nd Edition)
2nd Edition
ISBN: 9780134641621
Author: Dean R. Appling, Spencer J. Anthony-Cahill, Christopher K. Mathews
Publisher: PEARSON
Question
Book Icon
Chapter 18, Problem 2P
Interpretation Introduction

(a) Interpretation:

Substrate required by B enzyme should be identified.

Concept Introduction:

Biosynthesis of vitamin B12 or cobalamin has aerobic and anaerobic pathways. Aerobic is where the chemical pathway needs oxygen and later cobalt is added. In anaerobic pathway, cobalt is added in the beginning and requires no oxygen.Biosynthesis of B12 as shown in the diagram produces 5-methyltetrahydrofolate as substrate. And methylmalonate is the compound formed in genetic deficient animal's urine. When the C enzyme loses its affinity towards a substrate injecting large amount of Vitamin B12 is reduced. Homocysteine is released during urine excretion.

Interpretation Introduction

(b) Interpretation:

Compound excreted in urine because ofenzyme C deficiency in animals should be identified.

Concept Introduction:

Biosynthesis of vitamin B12 or cobalamin has aerobic and anaerobic pathways. Aerobic is where the chemical pathway needs oxygen and later cobalt is added. In anaerobic pathway, cobalt is added in the beginning and requires no oxygen. Biosynthesis of B12 as shown in the diagram produces 5-methyltetrahydrofolate as substrate. And methylmalonate is the compound formed in genetic deficient animal's urine. When the C enzyme loses its affinity towards a substrate injecting large amount of Vitamin B12 is reduced. Homocysteine is released during urine excretion.

Interpretation Introduction

(c) Interpretation:

Consistent alterations of genetic in the enzyme because of treatment by injecting B12 for the enzyme C deficiency in animals should be identified.

Concept Introduction:

Biosynthesis of vitamin B12 or cobalamin has aerobic and anaerobic pathways. Aerobic is where the chemical pathway needs oxygen and later cobalt is added. In anaerobic pathway, cobalt is added in the beginning and requires no oxygen. Biosynthesis of B12 as shown in the diagram produces 5-methyltetrahydrofolate as substrate. And methylmalonate is the compound formed in genetic deficient animal's urine. When the C enzyme loses its affinity towards a substrate injecting large amount of Vitamin B12 is reduced. Homocysteine is released during urine excretion.

Interpretation Introduction

(d) Interpretation:

Kinds of amino acid released during urine excretion of animals having genetic deficiency in animals should be identified.

Concept Introduction:

Biosynthesis of vitamin B12 or cobalamin has aerobic and anaerobic pathways. Aerobic is where the chemical pathway needs oxygen and later cobalt is added. In anaerobic pathway, cobalt is added in the beginning and requires no oxygen. Biosynthesis of B12 as shown in the diagram produces 5-methyltetrahydrofolate as substrate. And methylmalonate is the compound formed in genetic deficient animal's urine. When the C enzyme loses its affinity towards a substrate injecting large amount of Vitamin B12 is reduced. Homocysteine is released during urine excretion.

Blurred answer
Students have asked these similar questions
At a pH equal to the isoelectric point (pl) of alanine, the net charge of alanine is zero. Two structures can be drawn that have a net charge of zero, but the predominant form of alanine at its pl is zwitterionic. CH3 H,N CH3 ** H¸N-C H Zwitterionic H Uncharged OH Select statements that explain why alanine is predominantly zwitterionic at its pl. pk of alanine's amino group is more than its pl. pk of alanine's carboxyl group is more than its pl. PK of alanine's carboxyl group is less than its pl. pk of alanine's amino group is less than its pl. Correct Answer What fraction of alanine is in the completely uncharged form at its pl? 1 in 2.2 × 107 1 in 1.6 × 10² 1 in 4680 1 in 9460
How does a voltage-gated sodium channel work? Specifically, how and why does a change in voltage trigger their opening? Please be detailed
When sodium ions enter a neuron during depolarization, they trigger the opening of additional voltage-gated sodium channels nearby, creating a positive feedback loop where the influx of sodium ions further depolarizes the membrane, causing even more sodium channels to open and allowing more sodium ions to enter the cell, thus sustaining the depolarization process until the action potential peaks. But how and why exactly does the influx of sodium ions trigger more sodium channels to let in more sodium? Please explain
Knowledge Booster
Background pattern image
Similar questions
SEE MORE QUESTIONS
Recommended textbooks for you
Text book image
Biochemistry
Biochemistry
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:W. H. Freeman
Text book image
Lehninger Principles of Biochemistry
Biochemistry
ISBN:9781464126116
Author:David L. Nelson, Michael M. Cox
Publisher:W. H. Freeman
Text book image
Fundamentals of Biochemistry: Life at the Molecul...
Biochemistry
ISBN:9781118918401
Author:Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher:WILEY
Text book image
Biochemistry
Biochemistry
ISBN:9781305961135
Author:Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher:Cengage Learning
Text book image
Biochemistry
Biochemistry
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Cengage Learning
Text book image
Fundamentals of General, Organic, and Biological ...
Biochemistry
ISBN:9780134015187
Author:John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. Peterson
Publisher:PEARSON