The synthesis of a given molecule via aldol reaction is to be shown. Concept introduction: Every aldol addition produces a β-hydroxycarbonyl compound. A new C-C bond is formed via aldol addition. When an aldehyde is treated with a strong base, NaOH which produced β-hydroxycarbonyl compound. The carbonyl and the hydroxyl groups in the product are separated by two carbon atoms. It is a nucleophilic addition reaction, where the starting compound aldehyde required α hydrogen. The new C-C bond which is formed in α-hydroxy carbonyl the compound can be a disconnect to get two carbonyl precursors. And these aldehyde precursors can undergo an aldol addition to produce a target molecule.

Question

Want to see the full answer?

Answer 1

Question

Definition Definition Organic compounds that have a carbonyl group, C=O, as their functional group. The carbonyl group in aldehydes is placed at the end of the molecular structure, which means the C=O is attached to one hydrogen atom and an alkyl group or a benzene ring. Just like all the other homologous series in organic chemistry, the naming of aldehydes uses the suffix “-al”. The general molecular formula is C n H 2n O.

Chapter 18, Problem 18.23P

Interpretation Introduction

Interpretation:

The synthesis of a given molecule via aldol reaction is to be shown.

Concept introduction:

Every aldol addition produces a β-hydroxycarbonyl compound. A new C-C bond is formed via aldol addition. When an aldehyde is treated with a strong base, NaOH which produced β-hydroxycarbonyl compound. The carbonyl and the hydroxyl groups in the product are separated by two carbon atoms. It is a nucleophilic addition reaction, where the starting compound aldehyde required α hydrogen. The new C-C bond which is formed in α-hydroxy carbonyl the compound can be a disconnect to get two carbonyl precursors. And these aldehyde precursors can undergo an aldol addition to produce a target molecule.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

H Draw the product and the mechanism 1.) LDA + 2.) H30* H ○ excess OH

Given the first-order reaction: aA → products. State its kinetic equation.

Draw the product and the mechanism excess A. ob B. C. H*; .OH OH H*: ✓ OH H*; H₂O D. excess 8 1. LDA 2. H*

Answer 2

Question

Definition Definition Organic compounds that have a carbonyl group, C=O, as their functional group. The carbonyl group in aldehydes is placed at the end of the molecular structure, which means the C=O is attached to one hydrogen atom and an alkyl group or a benzene ring. Just like all the other homologous series in organic chemistry, the naming of aldehydes uses the suffix “-al”. The general molecular formula is C n H 2n O.

Chapter 18, Problem 18.23P

Interpretation Introduction

Interpretation:

The synthesis of a given molecule via aldol reaction is to be shown.

Concept introduction:

Every aldol addition produces a β-hydroxycarbonyl compound. A new C-C bond is formed via aldol addition. When an aldehyde is treated with a strong base, NaOH which produced β-hydroxycarbonyl compound. The carbonyl and the hydroxyl groups in the product are separated by two carbon atoms. It is a nucleophilic addition reaction, where the starting compound aldehyde required α hydrogen. The new C-C bond which is formed in α-hydroxy carbonyl the compound can be a disconnect to get two carbonyl precursors. And these aldehyde precursors can undergo an aldol addition to produce a target molecule.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 3

Question

Definition Definition Organic compounds that have a carbonyl group, C=O, as their functional group. The carbonyl group in aldehydes is placed at the end of the molecular structure, which means the C=O is attached to one hydrogen atom and an alkyl group or a benzene ring. Just like all the other homologous series in organic chemistry, the naming of aldehydes uses the suffix “-al”. The general molecular formula is C n H 2n O.

Chapter 18, Problem 18.23P

Interpretation Introduction

Interpretation:

The synthesis of a given molecule via aldol reaction is to be shown.

Concept introduction:

Every aldol addition produces a β-hydroxycarbonyl compound. A new C-C bond is formed via aldol addition. When an aldehyde is treated with a strong base, NaOH which produced β-hydroxycarbonyl compound. The carbonyl and the hydroxyl groups in the product are separated by two carbon atoms. It is a nucleophilic addition reaction, where the starting compound aldehyde required α hydrogen. The new C-C bond which is formed in α-hydroxy carbonyl the compound can be a disconnect to get two carbonyl precursors. And these aldehyde precursors can undergo an aldol addition to produce a target molecule.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 4

Question

Definition Definition Organic compounds that have a carbonyl group, C=O, as their functional group. The carbonyl group in aldehydes is placed at the end of the molecular structure, which means the C=O is attached to one hydrogen atom and an alkyl group or a benzene ring. Just like all the other homologous series in organic chemistry, the naming of aldehydes uses the suffix “-al”. The general molecular formula is C n H 2n O.

Chapter 18, Problem 18.23P

Interpretation Introduction